ATE475886T1 - Proteolipidmembran und lipidmembranen-biosensor - Google Patents
Proteolipidmembran und lipidmembranen-biosensorInfo
- Publication number
- ATE475886T1 ATE475886T1 AT06784359T AT06784359T ATE475886T1 AT E475886 T1 ATE475886 T1 AT E475886T1 AT 06784359 T AT06784359 T AT 06784359T AT 06784359 T AT06784359 T AT 06784359T AT E475886 T1 ATE475886 T1 AT E475886T1
- Authority
- AT
- Austria
- Prior art keywords
- membrane
- proteolipid
- biosensor
- lipid
- lipid membrane
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/5432—Liposomes or microcapsules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67052405P | 2005-04-12 | 2005-04-12 | |
| PCT/US2006/013926 WO2006127167A2 (en) | 2005-04-12 | 2006-04-12 | Proteolipid membrane & lipid membrane biosensor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE475886T1 true ATE475886T1 (de) | 2010-08-15 |
Family
ID=37395913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06784359T ATE475886T1 (de) | 2005-04-12 | 2006-04-12 | Proteolipidmembran und lipidmembranen-biosensor |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20060275825A1 (de) |
| EP (1) | EP1872129B1 (de) |
| JP (1) | JP4783422B2 (de) |
| CN (1) | CN101180541A (de) |
| AT (1) | ATE475886T1 (de) |
| AU (1) | AU2006249657B2 (de) |
| CA (1) | CA2604099C (de) |
| DE (1) | DE602006015793D1 (de) |
| NZ (1) | NZ562794A (de) |
| WO (1) | WO2006127167A2 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8111401B2 (en) | 1999-11-05 | 2012-02-07 | Robert Magnusson | Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats |
| US7167615B1 (en) | 1999-11-05 | 2007-01-23 | Board Of Regents, The University Of Texas System | Resonant waveguide-grating filters and sensors and methods for making and using same |
| US7094595B2 (en) | 2000-10-30 | 2006-08-22 | Sru Biosystems, Inc. | Label-free high-throughput optical technique for detecting biomolecular interactions |
| US7524625B2 (en) * | 2000-10-30 | 2009-04-28 | Sru Biosystems, Inc. | Real time binding analysis of antigens on a biosensor surface |
| US7575939B2 (en) | 2000-10-30 | 2009-08-18 | Sru Biosystems, Inc. | Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements |
| US7371562B2 (en) * | 2000-10-30 | 2008-05-13 | Sru Biosystems, Inc. | Guided mode resonant filter biosensor using a linear grating surface structure |
| US7927822B2 (en) | 2002-09-09 | 2011-04-19 | Sru Biosystems, Inc. | Methods for screening cells and antibodies |
| US7309614B1 (en) | 2002-12-04 | 2007-12-18 | Sru Biosystems, Inc. | Self-referencing biodetection method and patterned bioassays |
| US8298780B2 (en) | 2003-09-22 | 2012-10-30 | X-Body, Inc. | Methods of detection of changes in cells |
| NZ562794A (en) * | 2005-04-12 | 2010-07-30 | Sru Biosystems Inc | Proteolipid membrane & lipid membrane biosensor using a titanium surface |
| KR100755672B1 (ko) * | 2006-08-24 | 2007-09-05 | 삼성전자주식회사 | 기판 내에 형성된 프로브 셀 액티브를 포함하는 올리고머프로브 어레이 및 그 제조 방법 |
| US9134307B2 (en) | 2007-07-11 | 2015-09-15 | X-Body, Inc. | Method for determining ion channel modulating properties of a test reagent |
| CN101802611A (zh) | 2007-07-11 | 2010-08-11 | Sru生物系统公司 | 鉴别离子通道调节剂的方法 |
| CN101796403B (zh) * | 2007-09-07 | 2014-08-20 | 东丽株式会社 | 液体展开用板 |
| US8445217B2 (en) | 2007-09-20 | 2013-05-21 | Vanderbilt University | Free solution measurement of molecular interactions by backscattering interferometry |
| EP2223037A4 (de) | 2007-12-10 | 2016-08-03 | Molecular Sensing Inc | Temperaturstabiles interferometer |
| US8257936B2 (en) | 2008-04-09 | 2012-09-04 | X-Body Inc. | High resolution label free analysis of cellular properties |
| NZ590411A (en) | 2008-07-11 | 2013-07-26 | Universal Biosensors Pty Ltd | Enhanced immunoassay sensor |
| WO2010080710A2 (en) * | 2009-01-12 | 2010-07-15 | Molecular Sensing, Inc. | Sample collection and measurement in a single container by back scattering interferometry |
| US20100188665A1 (en) * | 2009-01-12 | 2010-07-29 | Molecular Sensing, Inc. | Methods and systems for interferometric analysis |
| WO2010129027A2 (en) * | 2009-05-04 | 2010-11-11 | Molecular Sensing, Inc. | Analysis of membrane component interactions |
| US9638632B2 (en) | 2010-06-11 | 2017-05-02 | Vanderbilt University | Multiplexed interferometric detection system and method |
| US9562853B2 (en) | 2011-02-22 | 2017-02-07 | Vanderbilt University | Nonaqueous backscattering interferometric methods |
| US9273949B2 (en) | 2012-05-11 | 2016-03-01 | Vanderbilt University | Backscattering interferometric methods |
| US20130330761A1 (en) | 2012-06-12 | 2013-12-12 | Celcuity, LLC | Whole cell assays and methods |
| WO2015089380A2 (en) | 2013-12-12 | 2015-06-18 | Celcuity Llc | Assays and methods for determining the responsiveness of an individual subject to a therapeutic agent |
| WO2016003936A1 (en) * | 2014-06-30 | 2016-01-07 | Biodesy, Inc. | Systems and methods for high throughput analysis of conformation in biological entities |
| EP3237906B8 (de) | 2014-12-23 | 2020-10-28 | Bluelight Therapeutics, Inc. | Befestigung von proteinen an schnittstellen zur verwendung in nicht-linearer optischer detektion |
| WO2016118812A1 (en) | 2015-01-23 | 2016-07-28 | Vanderbilt University | A robust interferometer and methods of using same |
| US10627396B2 (en) | 2016-01-29 | 2020-04-21 | Vanderbilt University | Free-solution response function interferometry |
| WO2017196891A1 (en) | 2016-05-09 | 2017-11-16 | Biodesy, Inc. | Methods and devices for detection of peripheral membrane protein interactions using nonlinear optical techniques |
| WO2018175251A1 (en) | 2017-03-20 | 2018-09-27 | Celcuity Llc | Methods of measuring signaling pathway activity for selection of therapeutic agents |
Family Cites Families (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8423204D0 (en) * | 1984-09-14 | 1984-10-17 | Comtech Res Unit | Assay technique and equipment |
| US5216680A (en) * | 1991-07-11 | 1993-06-01 | Board Of Regents, The University Of Texas System | Optical guided-mode resonance filter |
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| WO1996038726A1 (en) * | 1995-05-30 | 1996-12-05 | Ecole Polytechnique Federale De Lausanne (Epfl) | Covalently immobilized phospholipid bilayers on solid surfaces |
| GB9602542D0 (en) * | 1996-02-08 | 1996-04-10 | Fisons Plc | Analytical device |
| US5666197A (en) * | 1996-08-21 | 1997-09-09 | Polaroid Corporation | Apparatus and methods employing phase control and analysis of evanescent illumination for imaging and metrology of subwavelength lateral surface topography |
| US6645644B1 (en) * | 1996-10-17 | 2003-11-11 | The Trustees Of Princeton University | Enhanced bonding of phosphoric and phosphoric acids to oxidized substrates |
| US6146767A (en) * | 1996-10-17 | 2000-11-14 | The Trustees Of Princeton University | Self-assembled organic monolayers |
| DE59811600D1 (de) * | 1997-09-10 | 2004-07-29 | Artificial Sensing Instr Asi A | Optischer sensor und optisches verfahren zur charakterisierung einer chemischen und/oder biochemischen substanz |
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| US6684007B2 (en) * | 1998-10-09 | 2004-01-27 | Fujitsu Limited | Optical coupling structures and the fabrication processes |
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| US6541071B1 (en) * | 2000-03-23 | 2003-04-01 | Corning Incorporated | Method for fabricating supported bilayer-lipid membranes |
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| US20040219619A1 (en) * | 2000-07-21 | 2004-11-04 | Ester Fernandez-Salas | Methods of identifying compounds that alter toxin persistence and/or protease activity |
| US6977155B2 (en) * | 2000-08-10 | 2005-12-20 | Corning Incorporated | Arrays of biological membranes and methods and use thereof |
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| US6951715B2 (en) * | 2000-10-30 | 2005-10-04 | Sru Biosystems, Inc. | Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements |
| US7094595B2 (en) * | 2000-10-30 | 2006-08-22 | Sru Biosystems, Inc. | Label-free high-throughput optical technique for detecting biomolecular interactions |
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| US7175980B2 (en) * | 2000-10-30 | 2007-02-13 | Sru Biosystems, Inc. | Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities |
| US7524625B2 (en) * | 2000-10-30 | 2009-04-28 | Sru Biosystems, Inc. | Real time binding analysis of antigens on a biosensor surface |
| US20030092075A1 (en) * | 2000-10-30 | 2003-05-15 | Sru Biosystems, Llc | Aldehyde chemical surface activation processes and test methods for colorimetric resonant sensors |
| US7575939B2 (en) * | 2000-10-30 | 2009-08-18 | Sru Biosystems, Inc. | Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements |
| US6675654B2 (en) * | 2001-05-09 | 2004-01-13 | Endress + Hauser Gmbh + Co. Kg | Pressure sensing device with moisture filter |
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| US7927822B2 (en) * | 2002-09-09 | 2011-04-19 | Sru Biosystems, Inc. | Methods for screening cells and antibodies |
| US7863052B2 (en) * | 2005-08-11 | 2011-01-04 | Sru Biosystems, Inc. | Grating-based sensor combining label-free binding detection and fluorescence amplification and readout system for sensor |
| US20040091397A1 (en) * | 2002-11-07 | 2004-05-13 | Corning Incorporated | Multiwell insert device that enables label free detection of cells and other objects |
| US20040096914A1 (en) * | 2002-11-20 | 2004-05-20 | Ye Fang | Substrates with stable surface chemistry for biological membrane arrays and methods for fabricating thereof |
| US7309614B1 (en) * | 2002-12-04 | 2007-12-18 | Sru Biosystems, Inc. | Self-referencing biodetection method and patterned bioassays |
| US7254986B2 (en) * | 2002-12-13 | 2007-08-14 | General Electric Company | Sensor device for detection of dissolved hydrocarbon gases in oil filled high-voltage electrical equipment |
| US7497992B2 (en) * | 2003-05-08 | 2009-03-03 | Sru Biosystems, Inc. | Detection of biochemical interactions on a biosensor using tunable filters and tunable lasers |
| US8298780B2 (en) * | 2003-09-22 | 2012-10-30 | X-Body, Inc. | Methods of detection of changes in cells |
| JP2007510928A (ja) * | 2003-11-06 | 2007-04-26 | エス アール ユー バイオシステムズ,インコーポレイテッド | 高密度アミン機能化表面 |
| US6990259B2 (en) * | 2004-03-29 | 2006-01-24 | Sru Biosystems, Inc. | Photonic crystal defect cavity biosensor |
| EP1769230A2 (de) * | 2004-06-28 | 2007-04-04 | SRU Biosystems, Inc. | Integration von direkten bindungssensoren mit massenspektrometrie zur funktionellen und strukturellen charakterisierung von molekülen |
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| NZ562794A (en) * | 2005-04-12 | 2010-07-30 | Sru Biosystems Inc | Proteolipid membrane & lipid membrane biosensor using a titanium surface |
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| US7162125B1 (en) * | 2005-06-23 | 2007-01-09 | Sru Biosystems, Inc. | Optimized grating based biosensor and substrate combination |
| US7479404B2 (en) * | 2005-07-08 | 2009-01-20 | The Board Of Trustees Of The University Of Illinois | Photonic crystal biosensor structure and fabrication method |
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| US7483127B1 (en) * | 2005-08-08 | 2009-01-27 | Sru Biosystems, Inc. | Method and apparatus for generating an image of biomolecular sensor target area |
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| EP2041554A2 (de) * | 2006-07-07 | 2009-04-01 | The Board of Trustees of the University of Illinois | Ultraschallwellenlängenbereichsbiosensor aus photonischem kristall mit verbesserter oberfläche für das ansammelempfindlichkeitsverhältnis |
| JP2010508520A (ja) * | 2006-10-31 | 2010-03-18 | エス アール ユー バイオシステムズ,インコーポレイテッド | 官能基が付与された表面上の非特異的タンパク質結合をブロッキングする方法 |
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| US20080240543A1 (en) * | 2007-03-30 | 2008-10-02 | Wolfgang Ernst Gustav Budach | Calibration and normalization method for biosensors |
| AU2008242664B2 (en) * | 2007-04-19 | 2011-10-20 | Sru Biosystems, Inc. | Method for employing a biosensor to detect small molecules that bind directly to immobilized targets |
| US9134307B2 (en) * | 2007-07-11 | 2015-09-15 | X-Body, Inc. | Method for determining ion channel modulating properties of a test reagent |
| CN101802611A (zh) * | 2007-07-11 | 2010-08-11 | Sru生物系统公司 | 鉴别离子通道调节剂的方法 |
| US8268637B2 (en) * | 2008-01-11 | 2012-09-18 | The Board Of Trustees Of The University Of Illinois | Label-free biosensors based upon distributed feedback laser |
| US20090227469A1 (en) * | 2008-03-10 | 2009-09-10 | Conklin Bruce R | Cells and assays for use in detecting long qt syndrome |
| US8257936B2 (en) * | 2008-04-09 | 2012-09-04 | X-Body Inc. | High resolution label free analysis of cellular properties |
| EP2304500A1 (de) * | 2008-06-04 | 2011-04-06 | SRU Biosystems, Inc. | Detektion von promiskuitiven kleinen submikrometeraggregaten |
| US20100008826A1 (en) * | 2008-07-10 | 2010-01-14 | Sru Biosystems, Inc. | Biosensors featuring confinement of deposited material and intra-well self-referencing |
| WO2010087806A1 (en) * | 2009-02-02 | 2010-08-05 | Sru Biosystems, Inc | Efficient optical arrangement for illumination and detection of label-free biosensors and method to reduce interference fringes in label-free imaging |
| CA2761114A1 (en) * | 2009-05-15 | 2010-11-18 | Sru Biosystems, Inc. | Detection of changes in cell populations and mixed cell populations |
-
2006
- 2006-04-12 NZ NZ562794A patent/NZ562794A/en not_active IP Right Cessation
- 2006-04-12 US US11/403,128 patent/US20060275825A1/en not_active Abandoned
- 2006-04-12 DE DE602006015793T patent/DE602006015793D1/de not_active Expired - Lifetime
- 2006-04-12 EP EP06784359A patent/EP1872129B1/de not_active Expired - Lifetime
- 2006-04-12 JP JP2008506705A patent/JP4783422B2/ja not_active Expired - Fee Related
- 2006-04-12 CN CNA2006800115653A patent/CN101180541A/zh active Pending
- 2006-04-12 CA CA2604099A patent/CA2604099C/en not_active Expired - Fee Related
- 2006-04-12 AU AU2006249657A patent/AU2006249657B2/en not_active Ceased
- 2006-04-12 AT AT06784359T patent/ATE475886T1/de active
- 2006-04-12 WO PCT/US2006/013926 patent/WO2006127167A2/en not_active Ceased
-
2009
- 2009-03-30 US US12/414,048 patent/US20090192049A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006127167A2 (en) | 2006-11-30 |
| EP1872129A2 (de) | 2008-01-02 |
| WO2006127167A3 (en) | 2007-03-22 |
| HK1109804A1 (en) | 2008-06-20 |
| US20090192049A1 (en) | 2009-07-30 |
| CA2604099A1 (en) | 2006-11-30 |
| JP4783422B2 (ja) | 2011-09-28 |
| EP1872129B1 (de) | 2010-07-28 |
| AU2006249657B2 (en) | 2011-02-10 |
| DE602006015793D1 (de) | 2010-09-09 |
| NZ562794A (en) | 2010-07-30 |
| AU2006249657A1 (en) | 2006-11-30 |
| JP2008536148A (ja) | 2008-09-04 |
| CA2604099C (en) | 2011-02-15 |
| CN101180541A (zh) | 2008-05-14 |
| US20060275825A1 (en) | 2006-12-07 |
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