ATE466935T1 - Verfahren zur entfernung eines nichtmetallischen proteinhemmers aus einer flüssigen pharmazeutischen zubereitung - Google Patents
Verfahren zur entfernung eines nichtmetallischen proteinhemmers aus einer flüssigen pharmazeutischen zubereitungInfo
- Publication number
- ATE466935T1 ATE466935T1 AT07726469T AT07726469T ATE466935T1 AT E466935 T1 ATE466935 T1 AT E466935T1 AT 07726469 T AT07726469 T AT 07726469T AT 07726469 T AT07726469 T AT 07726469T AT E466935 T1 ATE466935 T1 AT E466935T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical preparation
- liquid pharmaceutical
- inhibitor
- removal
- protein inhibitor
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 7
- 239000007788 liquid Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 229940121649 protein inhibitor Drugs 0.000 title abstract 2
- 239000012268 protein inhibitor Substances 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 239000007790 solid phase Substances 0.000 abstract 2
- 102000012479 Serine Proteases Human genes 0.000 abstract 1
- 108010022999 Serine Proteases Proteins 0.000 abstract 1
- 108091005605 Vitamin K-dependent proteins Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
- C12N9/6408—Serine endopeptidases (3.4.21)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- General Engineering & Computer Science (AREA)
- Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06110412 | 2006-02-24 | ||
| PCT/EP2007/051711 WO2007096406A1 (en) | 2006-02-24 | 2007-02-22 | A method of removing a non-metallic protein inhibitor from a liquid pharmaceutical preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE466935T1 true ATE466935T1 (de) | 2010-05-15 |
Family
ID=36595910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07726469T ATE466935T1 (de) | 2006-02-24 | 2007-02-22 | Verfahren zur entfernung eines nichtmetallischen proteinhemmers aus einer flüssigen pharmazeutischen zubereitung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090111751A1 (de) |
| EP (1) | EP1989304B1 (de) |
| JP (1) | JP2009527536A (de) |
| AT (1) | ATE466935T1 (de) |
| DE (1) | DE602007006282D1 (de) |
| WO (1) | WO2007096406A1 (de) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3751605D1 (de) * | 1986-01-06 | 1996-01-04 | Blood Systems Inc | Therapeutisches Blutprodukt, Mittel und Verfahren zu dessen Erzeugung. |
| US5288612A (en) * | 1991-07-03 | 1994-02-22 | The Scripps Research Institute | Assay methods for detecting serum proteases, particularly activated protein C |
| SE505274C2 (sv) * | 1995-10-24 | 1997-07-28 | Sten Andersson | Användning av en hydrofob zeolit för avlägsnande av för injektionslösningar i läkemedelssammanhang använda konserveringsmedel från en proteinlösning |
-
2007
- 2007-02-22 JP JP2008555796A patent/JP2009527536A/ja not_active Withdrawn
- 2007-02-22 WO PCT/EP2007/051711 patent/WO2007096406A1/en active Application Filing
- 2007-02-22 AT AT07726469T patent/ATE466935T1/de not_active IP Right Cessation
- 2007-02-22 EP EP07726469A patent/EP1989304B1/de not_active Not-in-force
- 2007-02-22 DE DE602007006282T patent/DE602007006282D1/de active Active
- 2007-02-22 US US12/280,381 patent/US20090111751A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1989304A1 (de) | 2008-11-12 |
| WO2007096406A1 (en) | 2007-08-30 |
| JP2009527536A (ja) | 2009-07-30 |
| US20090111751A1 (en) | 2009-04-30 |
| EP1989304B1 (de) | 2010-05-05 |
| DE602007006282D1 (de) | 2010-06-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |