ATE430712T1 - Analyse von molekülen durch translokation durch eine beschichtete öffnung - Google Patents

Analyse von molekülen durch translokation durch eine beschichtete öffnung

Info

Publication number
ATE430712T1
ATE430712T1 AT04818058T AT04818058T ATE430712T1 AT E430712 T1 ATE430712 T1 AT E430712T1 AT 04818058 T AT04818058 T AT 04818058T AT 04818058 T AT04818058 T AT 04818058T AT E430712 T1 ATE430712 T1 AT E430712T1
Authority
AT
Austria
Prior art keywords
aperture
translocation
analysis
molecules
coated opening
Prior art date
Application number
AT04818058T
Other languages
English (en)
Inventor
Daniel Branton
Roy Gordon
Peng Chen
Toshiyuki Mitsui
Damon Farmer
Jene Golovchenko
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Application granted granted Critical
Publication of ATE430712T1 publication Critical patent/ATE430712T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B1/00—Devices without movable or flexible elements, e.g. microcapillary devices
    • B81B1/002—Holes characterised by their shape, in either longitudinal or sectional plane
    • B81B1/004—Through-holes, i.e. extending from one face to the other face of the wafer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
    • B81C1/00023—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems without movable or flexible elements
    • B81C1/00087—Holes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00—Specific applications of microelectromechanical systems
    • B81B2201/02—Sensors
    • B81B2201/0214—Biosensors; Chemical sensors

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Analytical Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nanotechnology (AREA)
  • Computer Hardware Design (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physical Vapour Deposition (AREA)
  • Executing Machine-Instructions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT04818058T 2003-12-19 2004-12-17 Analyse von molekülen durch translokation durch eine beschichtete öffnung ATE430712T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53142903P 2003-12-19 2003-12-19
PCT/US2004/042896 WO2005061373A1 (en) 2003-12-19 2004-12-17 Analysis of molecules by translocation through a coated aperture

Publications (1)

Publication Number Publication Date
ATE430712T1 true ATE430712T1 (de) 2009-05-15

Family

ID=34710225

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04818058T ATE430712T1 (de) 2003-12-19 2004-12-17 Analyse von molekülen durch translokation durch eine beschichtete öffnung

Country Status (4)

Country Link
EP (1) EP1708957B1 (de)
AT (1) ATE430712T1 (de)
DE (1) DE602004021033D1 (de)
WO (1) WO2005061373A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3543357A1 (de) 2007-05-08 2019-09-25 Trustees of Boston University Chemische funktionalisierung von festkörpernanoporen und nanoporenarrays und anwendungen davon
CA2750879C (en) 2009-01-30 2018-05-22 Oxford Nanopore Technologies Limited Adaptors for nucleic acid constructs in transmembrane sequencing
CN102482330A (zh) 2009-01-30 2012-05-30 牛津纳米孔技术有限公司 酶突变体
GB0905140D0 (en) 2009-03-25 2009-05-06 Isis Innovation Method
US9127313B2 (en) 2009-12-01 2015-09-08 Oxford Nanopore Technologies Limited Biochemical analysis instrument
EP2580588B1 (de) 2010-06-08 2014-09-24 President and Fellows of Harvard College Nanoporen-vorrichtung mit graphengetragener künstlicher lipidmembran
EP2622343B1 (de) 2010-10-01 2016-01-20 Oxford Nanopore Technologies Limited Biochemisches analysegerät und drehventil
WO2014197329A1 (en) * 2013-06-03 2014-12-11 Trustees Of Boston University Fiber coated nanopores
GB201811623D0 (en) 2018-07-16 2018-08-29 Univ Oxford Innovation Ltd Molecular hopper
GB201821155D0 (en) 2018-12-21 2019-02-06 Oxford Nanopore Tech Ltd Method
JP2024081540A (ja) * 2022-12-06 2024-06-18 株式会社アドバンテスト ポアチップおよび微粒子測定システム
WO2024165853A1 (en) 2023-02-07 2024-08-15 Oxford University Innovation Limited Method of characterising a peptide, polypeptide or protein using a nanopore

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627067B1 (en) * 1999-06-22 2003-09-30 President And Fellows Of Harvard College Molecular and atomic scale evaluation of biopolymers
NL1022855C2 (nl) * 2003-03-05 2004-09-07 Univ Delft Tech Werkwijze en inrichting voor het gecontroleerd vervaardigen van openingen op nanometerschaal.

Also Published As

Publication number Publication date
WO2005061373A1 (en) 2005-07-07
EP1708957B1 (de) 2009-05-06
DE602004021033D1 (de) 2009-06-18
EP1708957A1 (de) 2006-10-11

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