ATE425253T1 - TRIBONECTINS - Google Patents

TRIBONECTINS

Info

Publication number
ATE425253T1
ATE425253T1 AT00926303T AT00926303T ATE425253T1 AT E425253 T1 ATE425253 T1 AT E425253T1 AT 00926303 T AT00926303 T AT 00926303T AT 00926303 T AT00926303 T AT 00926303T AT E425253 T1 ATE425253 T1 AT E425253T1
Authority
AT
Austria
Prior art keywords
tribonectins
tribosupplementation
tribonectin
injured
administering
Prior art date
Application number
AT00926303T
Other languages
German (de)
Inventor
Gregory Jay
Original Assignee
Rhode Island Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23152784&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE425253(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhode Island Hospital filed Critical Rhode Island Hospital
Application granted granted Critical
Publication of ATE425253T1 publication Critical patent/ATE425253T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Conductive Materials (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

Abstract

The invention features a tribonectin and a method of tribosupplementation carried out by administering tribonectins directly to an injured or arthritic joint.
AT00926303T 1999-04-23 2000-04-24 TRIBONECTINS ATE425253T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/298,970 US6743774B1 (en) 1999-04-23 1999-04-23 Tribonectins

Publications (1)

Publication Number Publication Date
ATE425253T1 true ATE425253T1 (en) 2009-03-15

Family

ID=23152784

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00926303T ATE425253T1 (en) 1999-04-23 2000-04-24 TRIBONECTINS

Country Status (9)

Country Link
US (6) US6743774B1 (en)
EP (1) EP1173567B2 (en)
JP (5) JP2003500022A (en)
AT (1) ATE425253T1 (en)
AU (1) AU781564B2 (en)
CA (1) CA2367750C (en)
DE (1) DE60041761D1 (en)
ES (1) ES2324199T5 (en)
WO (1) WO2000064930A2 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743774B1 (en) * 1999-04-23 2004-06-01 Rhode Island Hospital Tribonectins
EP1255781A1 (en) * 2000-02-09 2002-11-13 Glaxo Group Limited Antibody binding superficial zone protein and their uses in diagnosis and screening methods
GB0003092D0 (en) 2000-02-10 2000-03-29 Glaxo Group Ltd Superficial zone protein-binding molecules and uses thereof
US20030180948A1 (en) * 2000-12-29 2003-09-25 Hutchins Jeff T. Superficial zone protein and methods of making and using same
EP1401481A1 (en) * 2001-06-14 2004-03-31 Novo Nordisk A/S Mucosal repair by tff dimer peptides
US20060240037A1 (en) * 2003-06-04 2006-10-26 Edward Fey Methods and compositions for the treatment and prevention of degenerative joint disorders
MXPA06001658A (en) * 2003-08-14 2006-04-28 Wyeth Corp Recombinant lubricin molecules and uses thereof.
US20090155200A1 (en) * 2004-04-20 2009-06-18 Jay Gregory D Methods of promoting cartilage healing or cartilage integration
JP2008507553A (en) * 2004-07-23 2008-03-13 ミューコサル セラピューティクス リミテッド ライアビリディ カンパニー Compositions and methods for viscous replenishment
US20080139458A1 (en) * 2004-12-03 2008-06-12 Jay Gregory D Methods of Treatment For Injured or Diseased Joints
US20070111327A1 (en) * 2005-05-05 2007-05-17 Jay Gregory D Methods of detecting lubricin
CA2652549A1 (en) * 2006-05-17 2007-12-13 Stryker Corporation Use of a soluble morphogenic protein complex for treating cartilage defects
US20090068247A1 (en) * 2007-09-12 2009-03-12 Mucosal Therapeutics Biocompatible devices coated with a tribonectin and methods for their production
US20090104148A1 (en) * 2007-09-18 2009-04-23 Jay Gregory D Treatment and prevention of joint disease
ES2530723T3 (en) 2008-05-07 2015-03-04 Univ California Therapeutic replacement and enrichment of ocular surface lubrication
US8980840B2 (en) 2009-01-13 2015-03-17 Schepens Eye Research Institute Therapeutic modulation of vaginal epithelium boundary lubrication
TW201031412A (en) * 2009-01-29 2010-09-01 Riken Combined preparation for treating joint diseases
US9730865B2 (en) 2009-05-22 2017-08-15 Lubris, Llc Application and uses of PRG4 and therapeutic modulation thereof
ES2627103T3 (en) 2010-01-19 2017-07-26 Lubris Llc Oral care compositions and methods
US8716204B2 (en) 2010-07-27 2014-05-06 Zimmer, Inc. Synthetic synovial fluid compositions and methods for making the same
US20130116186A1 (en) * 2011-10-04 2013-05-09 Rhode Island Hospital, A Lifespan Partner Lubricin injections to maintain cartilage health
US20150361452A1 (en) 2013-01-25 2015-12-17 Baylor College Of Medicine A Helper-Dependent Adenoviral Gene Therapy Delivery and Expression System
WO2015060935A1 (en) 2013-10-22 2015-04-30 Lubris, Llc Control of rheological properties of mixed hyaluronate/lubricin solutions
US10500250B2 (en) 2013-11-26 2019-12-10 Lubris Llc Compositions and methods for inhibiting intercellular interactions
EP3718559A1 (en) 2015-01-26 2020-10-07 Lubris LLC Use of prg4 as an anti-inflammatory agent
SI3300482T1 (en) 2015-05-19 2021-11-30 Lubris Llc Use of prg4 to improve dynamic visual acuity and higher order aberrations
DK3402530T3 (en) * 2016-01-13 2020-11-23 Genzyme Corp RECOMBINANT AAV VECTORS EXPRESSING BONE PROTECTIVE GENES, INCLUDING HAS2 AND LUBRICIN, WHICH ARE USABLE FOR THE TREATMENT OF OSTEOARTHRITIS AND RELATED JOINT CONDITIONS OF PATTEDY
EP3420354A1 (en) 2016-02-23 2019-01-02 Lynxon AB Method of diagnosing arthritis or other joint degrading disease
BR112022016481A2 (en) 2020-02-24 2022-10-25 Novartis Ag PURIFICATION OF RECOMBINANTLY PRODUCED POLYPEPTIDES
JP7063369B2 (en) * 2020-12-07 2022-05-09 株式会社三洋物産 Pachinko machine
WO2023212598A1 (en) 2022-04-27 2023-11-02 Lubris Llc Methods of making polymer films

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2734862A (en) 1956-02-14 Synthetic casein fiber elastic grease
US2487377A (en) 1948-04-17 1949-11-08 Socony Vacuum Oil Co Inc Lubricant
US2878184A (en) 1953-12-29 1959-03-17 Rockwell Mfg Co Hydrocarbon resistant glycerol base lubricant
AR207237A1 (en) 1974-02-25 1976-09-22 Thomas A PROCEDURE FOR OBTAINING SOLUBLE LYOPHILIZED STABLE BIOLOGICAL EXTRACTS CONSTITUTED BY THERMORE RESISTANT PROTEIN COMPLEXES
WO1981002977A1 (en) 1980-04-25 1981-10-29 Orthana Kemisk Fab As Sterilized,preserved,stable mucine-containing solutions and sterilization method
IL68218A (en) * 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
US5403592A (en) * 1987-08-25 1995-04-04 Macnaught Pty Limited Lubricant composition for rheumatism
GB8803697D0 (en) 1988-02-17 1988-03-16 Deltanine Research Ltd Clinical developments using amniotic membrane cells
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5260417A (en) 1989-04-03 1993-11-09 Genetics Institute, Inc. Megakaryocyte growth promoting activity protein
US6433142B1 (en) * 1989-08-08 2002-08-13 Genetics Institute, Llc Megakaryocyte stimulating factors
US5326558A (en) 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
CA2060223C (en) 1991-02-12 1999-07-20 Clarence C. Lee Injectable medical lubricating fluid composition and method of use
JPH04278061A (en) 1991-03-05 1992-10-02 Suntory Ltd Nutritious food
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
US5515590A (en) 1994-07-19 1996-05-14 University Of Kentucky Research Foundation Method for reducing the generation of wear particulates from an implant
US5709020A (en) 1994-07-19 1998-01-20 University Of Kentucky Research Foundation Method for reducing the generation of wear particulates from an implant
US5510122A (en) 1994-09-28 1996-04-23 The Research Foundation Of State University Of New York Preparation and use of whole saliva
FR2726188B1 (en) * 1994-11-02 1996-12-20 Inst Vaisseaux Et Du Sang GLYCOSAMINOGLYCAN / MEGACARYOCYTA GROWTH FACTOR COMPOSITION, USE IN THERAPEUTICS
US5639734A (en) 1994-12-20 1997-06-17 Esko; Jeffrey D. Disaccharide inflammation inhibitors and uses thereof
US6096728A (en) 1996-02-09 2000-08-01 Amgen Inc. Composition and method for treating inflammatory diseases
AT405477B (en) 1996-04-03 1999-08-25 Norbert Mag Fuchs COMBINATION PREPARATION
WO1998018491A1 (en) 1996-10-28 1998-05-07 BURGSTINER, Jacqueline, Cook Methods and compositions for dietary supplementation
US6960562B2 (en) 1999-04-23 2005-11-01 Rhode Island Hospital, A Lifespan Partner Tribonectin polypeptides and uses thereof
US6743774B1 (en) 1999-04-23 2004-06-01 Rhode Island Hospital Tribonectins
US7001881B1 (en) 1999-04-23 2006-02-21 Rhode Island Hospital Tribonectins
JP2004517030A (en) 1999-05-24 2004-06-10 アバロン バイオサイエンシーズ， インコーポレイテッド Glycosyltransferase inhibitors
WO2001007068A1 (en) 1999-07-23 2001-02-01 Case Western Reserve University Novel methods and reagents for the treatment of osteoarthritis
US6291533B1 (en) 1999-12-22 2001-09-18 Vitamerica, Inc. Dietary supplements for each specific blood type
GB0003092D0 (en) 2000-02-10 2000-03-29 Glaxo Group Ltd Superficial zone protein-binding molecules and uses thereof
US20030180948A1 (en) 2000-12-29 2003-09-25 Hutchins Jeff T. Superficial zone protein and methods of making and using same
WO2003000056A1 (en) 2001-06-25 2003-01-03 Inspire Pharmaceuticals, Inc. Joint lubrication with p2y purinergic receptor agonists
GB2381750A (en) 2001-10-10 2003-05-14 Inspire Pharmaceuticals Inc Treatment for enhancing joint lubrication
US20030224386A1 (en) 2001-12-19 2003-12-04 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of rheumatoid arthritis
MXPA06001658A (en) 2003-08-14 2006-04-28 Wyeth Corp Recombinant lubricin molecules and uses thereof.
US20070275032A1 (en) 2004-03-05 2007-11-29 Synthes (U.S.A.) Use Of A Mixture For The Production Of An Agent For Treating Defective Or Degenerated Cartilage In The Production Of Natural Cartilage Replacement In Vitro
JP2008507553A (en) 2004-07-23 2008-03-13 ミューコサル セラピューティクス リミテッド ライアビリディ カンパニー Compositions and methods for viscous replenishment
US20070111327A1 (en) 2005-05-05 2007-05-17 Jay Gregory D Methods of detecting lubricin

Also Published As

Publication number Publication date
AU4485200A (en) 2000-11-10
DE60041761D1 (en) 2009-04-23
EP1173567A2 (en) 2002-01-23
JP2012070738A (en) 2012-04-12
CA2367750C (en) 2013-10-22
JP5909592B2 (en) 2016-04-26
US20040229804A1 (en) 2004-11-18
US20100048458A1 (en) 2010-02-25
EP1173567B1 (en) 2009-03-11
JP2003500022A (en) 2003-01-07
ES2324199T5 (en) 2013-03-20
JP2016041769A (en) 2016-03-31
US20140179611A1 (en) 2014-06-26
JP2014144015A (en) 2014-08-14
JP2016172760A (en) 2016-09-29
AU781564B2 (en) 2005-06-02
EP1173567B2 (en) 2012-10-31
CA2367750A1 (en) 2000-11-02
US6743774B1 (en) 2004-06-01
US8680057B2 (en) 2014-03-25
US8026346B2 (en) 2011-09-27
US20130072435A1 (en) 2013-03-21
WO2000064930A3 (en) 2001-01-25
US7618941B2 (en) 2009-11-17
ES2324199T3 (en) 2009-08-03
US20100204087A1 (en) 2010-08-12
WO2000064930A2 (en) 2000-11-02

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