ATE39416T1 - SOLVENT-FREE, AQUEOUS NITROGLYCEROL SOLUTION. - Google Patents

SOLVENT-FREE, AQUEOUS NITROGLYCEROL SOLUTION.

Info

Publication number
ATE39416T1
ATE39416T1 AT83109887T AT83109887T ATE39416T1 AT E39416 T1 ATE39416 T1 AT E39416T1 AT 83109887 T AT83109887 T AT 83109887T AT 83109887 T AT83109887 T AT 83109887T AT E39416 T1 ATE39416 T1 AT E39416T1
Authority
AT
Austria
Prior art keywords
solution
free
aqueous
nitroglycerol
solvent
Prior art date
Application number
AT83109887T
Other languages
German (de)
Inventor
Kurt Burghart
Original Assignee
Pohl Boskamp Gmbh Chem Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6175236&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE39416(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pohl Boskamp Gmbh Chem Pharma filed Critical Pohl Boskamp Gmbh Chem Pharma
Application granted granted Critical
Publication of ATE39416T1 publication Critical patent/ATE39416T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

1. Aqueous nitro-glycerine solution, which is free from solubilizers and organic solvents, characterised in that it contains from 0.8 to 1.1 mg and preferably 1 mg of nitro-glycerine/ml of solution.
AT83109887T 1982-10-08 1983-10-04 SOLVENT-FREE, AQUEOUS NITROGLYCEROL SOLUTION. ATE39416T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823237284 DE3237284A1 (en) 1982-10-08 1982-10-08 SOLVENT-FREE, AQUEOUS NITROGLYCERIN SOLUTION
EP83109887A EP0108248B2 (en) 1982-10-08 1983-10-04 Aqueous nitroglycerine solution free of solubilizers

Publications (1)

Publication Number Publication Date
ATE39416T1 true ATE39416T1 (en) 1989-01-15

Family

ID=6175236

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83109887T ATE39416T1 (en) 1982-10-08 1983-10-04 SOLVENT-FREE, AQUEOUS NITROGLYCEROL SOLUTION.

Country Status (4)

Country Link
EP (1) EP0108248B2 (en)
AT (1) ATE39416T1 (en)
AU (1) AU1979283A (en)
DE (1) DE3237284A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4007705C1 (en) * 1990-03-10 1991-09-26 G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De
EP2878310B1 (en) 2013-11-29 2017-01-11 G. Pohl-Boskamp GmbH & Co. KG Sprayable aqueous composition comprising glyceryl trinitrate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2301664C3 (en) * 1973-01-13 1979-07-12 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Oral medicine containing nitroglycerin
JPS599539B2 (en) * 1979-11-13 1984-03-03 日本化薬株式会社 Nitroglycerin aqueous solution and its manufacturing method
DE3109783C2 (en) * 1981-03-13 1987-04-02 Schwarz GmbH, 4019 Monheim Process for the preparation of an ethanol-free nitroglycerin solution with a concentration of about 1 mg nitroglycerin/ml

Also Published As

Publication number Publication date
DE3237284A1 (en) 1984-04-12
DE3237284C2 (en) 1990-05-31
AU1979283A (en) 1984-04-12
EP0108248A3 (en) 1984-09-05
EP0108248A2 (en) 1984-05-16
EP0108248B1 (en) 1988-12-28
EP0108248B2 (en) 1999-09-15

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee