ATE383T1 - NEW 1,2,4-TRIAZOLE DERIVATIVES, A PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. - Google Patents

NEW 1,2,4-TRIAZOLE DERIVATIVES, A PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Info

Publication number
ATE383T1
ATE383T1 AT79103843T AT79103843T ATE383T1 AT E383 T1 ATE383 T1 AT E383T1 AT 79103843 T AT79103843 T AT 79103843T AT 79103843 T AT79103843 T AT 79103843T AT E383 T1 ATE383 T1 AT E383T1
Authority
AT
Austria
Prior art keywords
manufacture
pharmaceutical compositions
compositions containing
alkyl
triazole derivatives
Prior art date
Application number
AT79103843T
Other languages
German (de)
Inventor
Amedeo Omodei-Sale'
Pietro Consonni
Giulio Galliani
Original Assignee
Gruppo Lepetit S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit S.P.A. filed Critical Gruppo Lepetit S.P.A.
Application granted granted Critical
Publication of ATE383T1 publication Critical patent/ATE383T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Novel 1,2,4-triazole derivatives are described having the following formula <CHEM> wherein R represents hydrogen or methyl, R1 stands for hydrogen or (C1-C4)alkyl, or R and R1 taken together may represent a further bond between the carbon atom and the oxygen atom, R2 and R4 each independently, represent hydrogen, chloro, fluoro, bromo, (C1-C4)alkyl or (C1-C4)alkoxy, R3 stands for (C1-C4)alkyl, (C1-C4)alkoxy, allyloxy propargyloxy, trifluoromethyl, phenyl, chloro, fluoro, bromo or dimethylamino or R3 and R4 taken together may represent a methylenedioxy group. Also described is a process for their manufacture. Use of the novel compounds as antireproductive agents and pharmaceutical compositions containing them as active ingredient are also claimed.
AT79103843T 1978-10-30 1979-10-08 NEW 1,2,4-TRIAZOLE DERIVATIVES, A PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. ATE383T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7842416 1978-10-30
EP79103843A EP0011129B1 (en) 1978-10-30 1979-10-08 New 1,2,4-triazole derivatives, a process for their manufacture and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ATE383T1 true ATE383T1 (en) 1981-11-15

Family

ID=10500682

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79103843T ATE383T1 (en) 1978-10-30 1979-10-08 NEW 1,2,4-TRIAZOLE DERIVATIVES, A PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Country Status (9)

Country Link
US (1) US4409388A (en)
EP (1) EP0011129B1 (en)
JP (1) JPS5562076A (en)
AT (1) ATE383T1 (en)
BE (1) BE879727A (en)
CH (1) CH649082A5 (en)
DE (1) DE2961326D1 (en)
FR (1) FR2440363A1 (en)
IT (1) IT1207255B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888350A (en) * 1978-10-30 1989-12-19 Gruppo Lepetit S.P.A. New acyl-1H-1,2,4-triazole derivatives
AU557034B2 (en) * 1981-10-20 1986-12-04 Gruppo Lepetit S.P.A. 3,5-diphenyl-1h-1,2,4-trazoles with contragestational
IT1292092B1 (en) * 1997-06-05 1999-01-25 Geange Ltd USE OF NITROGEN AROMATIC HETEROCYCLIC DERIVATIVES IN THE TOPICAL TREATMENT OF EPITHELIAL TISSUES
KR100467668B1 (en) * 2002-08-07 2005-01-24 씨제이 주식회사 1,2,4-Triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU508198A3 (en) * 1971-07-22 1976-03-25 Группо Лепетит С.П.А. (Фирма) Method for preparing 1,2,4-triazole derivatives
US4151169A (en) * 1972-07-17 1979-04-24 Gruppo Lepetit Process for preparing substituted 1,2,4-triazole derivatives
GB1579352A (en) * 1977-05-06 1980-11-19 Lepetit Spa 3,5-disubstituted-1h-1,2,4-triazoles

Also Published As

Publication number Publication date
IT7926364A0 (en) 1979-10-10
EP0011129A1 (en) 1980-05-28
DE2961326D1 (en) 1982-01-14
CH649082A5 (en) 1985-04-30
EP0011129B1 (en) 1981-11-11
BE879727A (en) 1980-04-30
US4409388A (en) 1983-10-11
IT1207255B (en) 1989-05-17
JPS6258354B2 (en) 1987-12-05
FR2440363A1 (en) 1980-05-30
JPS5562076A (en) 1980-05-10
FR2440363B1 (en) 1983-10-28

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