ATE38378T1 - Verfahren zur herstellung von n-acetyl-paminophenol. - Google Patents
Verfahren zur herstellung von n-acetyl-paminophenol.Info
- Publication number
- ATE38378T1 ATE38378T1 AT85307964T AT85307964T ATE38378T1 AT E38378 T1 ATE38378 T1 AT E38378T1 AT 85307964 T AT85307964 T AT 85307964T AT 85307964 T AT85307964 T AT 85307964T AT E38378 T1 ATE38378 T1 AT E38378T1
- Authority
- AT
- Austria
- Prior art keywords
- acetyl
- aminophenol
- acetic acid
- paminophenol
- crude
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 12
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 4
- PLIKAWJENQZMHA-UHFFFAOYSA-N 4-aminophenol Chemical compound NC1=CC=C(O)C=C1 PLIKAWJENQZMHA-UHFFFAOYSA-N 0.000 abstract 2
- 239000012452 mother liquor Substances 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000000622 liquid--liquid extraction Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000000638 solvent extraction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP85307964A EP0221216B1 (de) | 1985-11-01 | 1985-11-01 | Verfahren zur Herstellung von N-Acetyl-P-aminophenol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE38378T1 true ATE38378T1 (de) | 1988-11-15 |
Family
ID=8194423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85307964T ATE38378T1 (de) | 1985-11-01 | 1985-11-01 | Verfahren zur herstellung von n-acetyl-paminophenol. |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0221216B1 (de) |
| AT (1) | ATE38378T1 (de) |
| DE (1) | DE3565979D1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0320484A3 (de) * | 1987-12-09 | 1990-09-26 | Rhone-Poulenc Chimie | Reinigung von N-acetyl-aminophenolen |
| CN107790078B (zh) * | 2017-12-08 | 2024-03-19 | 南京大学 | 一种生产对乙酰氨基酚的装置及工艺 |
| CN111170880A (zh) * | 2020-01-06 | 2020-05-19 | 河北冀衡(集团)药业有限公司 | 一种对乙酰氨基酚的生产系统和方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2653158A (en) * | 1951-06-29 | 1953-09-22 | Standard Oil Dev Co | Preparation of acyl p-amino-phenols |
| DE1493727A1 (de) * | 1965-07-16 | 1969-06-19 | Bayer Ag | Verfahren zur Herstellung von besonders reinem p-Acetaminophenol |
| US3917695A (en) * | 1973-02-20 | 1975-11-04 | Mallinckrodt Inc | Preparation of N-acetyl-p-aminophenol |
| US4139562A (en) * | 1978-03-13 | 1979-02-13 | Mitsui Toatsu Chemicals, Inc. | Process for purifying crude p-aminophenol |
-
1985
- 1985-11-01 DE DE8585307964T patent/DE3565979D1/de not_active Expired
- 1985-11-01 AT AT85307964T patent/ATE38378T1/de not_active IP Right Cessation
- 1985-11-01 EP EP85307964A patent/EP0221216B1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0221216A1 (de) | 1987-05-13 |
| DE3565979D1 (en) | 1988-12-08 |
| EP0221216B1 (de) | 1988-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EELA | Cancelled due to lapse of time |