ATE37787T1 - Behandlung von diabetes und anderen symptomen von hypercorticoidismus unter verwendung einer synergistischen mischung von etiocholanolonen und oestrogen. - Google Patents
Behandlung von diabetes und anderen symptomen von hypercorticoidismus unter verwendung einer synergistischen mischung von etiocholanolonen und oestrogen.Info
- Publication number
- ATE37787T1 ATE37787T1 AT84115177T AT84115177T ATE37787T1 AT E37787 T1 ATE37787 T1 AT E37787T1 AT 84115177 T AT84115177 T AT 84115177T AT 84115177 T AT84115177 T AT 84115177T AT E37787 T1 ATE37787 T1 AT E37787T1
- Authority
- AT
- Austria
- Prior art keywords
- hypercorticoidism
- diabetes
- etiocholanolones
- oestrogen
- symptoms
- Prior art date
Links
- 208000037171 Hypercorticoidism Diseases 0.000 title abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 2
- 239000000262 estrogen Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 230000002195 synergetic effect Effects 0.000 title 1
- QGXBDMJGAMFCBF-BNSUEQOYSA-N 3alpha-hydroxy-5beta-androstan-17-one Chemical compound C1[C@H](O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC[C@@H]21 QGXBDMJGAMFCBF-BNSUEQOYSA-N 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- QGXBDMJGAMFCBF-XRJZGPCZSA-N epietiocholanolone Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC[C@@H]21 QGXBDMJGAMFCBF-XRJZGPCZSA-N 0.000 abstract 1
- 229940011871 estrogen Drugs 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 239000011885 synergistic combination Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/566,222 US4507289A (en) | 1983-12-28 | 1983-12-28 | Treatment of diabetes and other symptoms of hypercorticoidism using a synergistic combination of etiocholanolones and estrogen |
| EP84115177A EP0148436B1 (de) | 1983-12-28 | 1984-12-11 | Behandlung von Diabetes und anderen Symptomen von Hypercorticoidismus unter Verwendung einer synergistischen Mischung von Etiocholanolonen und Oestrogen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE37787T1 true ATE37787T1 (de) | 1988-10-15 |
Family
ID=24262008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT84115177T ATE37787T1 (de) | 1983-12-28 | 1984-12-11 | Behandlung von diabetes und anderen symptomen von hypercorticoidismus unter verwendung einer synergistischen mischung von etiocholanolonen und oestrogen. |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4507289A (de) |
| EP (1) | EP0148436B1 (de) |
| AT (1) | ATE37787T1 (de) |
| DE (1) | DE3474510D1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666898A (en) * | 1983-12-28 | 1987-05-19 | Jackson Lab. | Treatment of obesity, diabetes and other symptoms of hypercorticoidism using etiocholanolones |
| US4602008A (en) * | 1984-12-14 | 1986-07-22 | Progenics, Inc. | Alkylated etiocholanolones and use as an anti-diabetic, anti-obesity and erythropoietic agent |
| US4812447A (en) * | 1985-10-22 | 1989-03-14 | City Of Hope | Method for the treatment of nervous system degeneration |
| EP0261891A3 (de) * | 1986-09-22 | 1990-09-05 | Progenics, Inc. | Etiochiolandion enthaltende pharmazeutische Zusammensetzungen |
| NL194728C (nl) * | 1987-04-16 | 2003-01-07 | Hollis Eden Pharmaceuticals | Farmaceutisch preparaat geschikt voor de profylaxe of therapie van een retrovirale infectie of een complicatie of gevolg daarvan. |
| US5006517A (en) * | 1987-12-01 | 1991-04-09 | Progenics, Inc. | Treatment of Prader-Willi syndrome |
| US5753237A (en) * | 1989-09-25 | 1998-05-19 | University Of Utah Research Foundation | Method for augmenting immunological responses |
| AUPN058895A0 (en) * | 1995-01-16 | 1995-02-09 | Garvan Institute Of Medical Research | Diagnostic method |
| HUP9801834A3 (en) | 1995-10-12 | 2000-06-28 | Supergen Inc Emeryville | Liposome formulations of 5beta steroids |
| US5824668A (en) * | 1996-11-07 | 1998-10-20 | Supergen, Inc. | Formulation for administration of steroid compounds |
| JP2002507960A (ja) * | 1995-11-13 | 2002-03-12 | スーパーゲン インク. | ステロイド化合物投与のための改良された製剤 |
| US5635535A (en) * | 1996-04-05 | 1997-06-03 | Wagstaff; Robert K. | Method for increasing blood glucose levels |
| US20030083231A1 (en) * | 1998-11-24 | 2003-05-01 | Ahlem Clarence N. | Blood cell deficiency treatment method |
| US6667299B1 (en) | 2000-03-16 | 2003-12-23 | Hollis-Eden Pharmaceuticals, Inc. | Pharmaceutical compositions and treatment methods |
| AU7896100A (en) * | 1999-10-14 | 2001-04-23 | Endorecherche Inc. | Selective estrogen receptor modulators in the treatment or reduction of the riskof acquiring hypertension, cardiovascular diseases, and insulin resistance |
| RU2251426C1 (ru) * | 2003-09-18 | 2005-05-10 | Цыганков Владимир Владимирович | Способ получения инсулина из природного источника и инсулин |
| US20060234993A1 (en) * | 2005-04-13 | 2006-10-19 | Eric Marchewitz | Use of androstane derivatives for enhancing physical performance |
| JPWO2011007882A1 (ja) * | 2009-07-16 | 2012-12-27 | 国立大学法人九州大学 | インスリン産生細胞誘導剤、グルコース取込み促進剤および糖尿病または糖尿病合併症の治療薬 |
-
1983
- 1983-12-28 US US06/566,222 patent/US4507289A/en not_active Expired - Lifetime
-
1984
- 1984-12-11 EP EP84115177A patent/EP0148436B1/de not_active Expired
- 1984-12-11 AT AT84115177T patent/ATE37787T1/de not_active IP Right Cessation
- 1984-12-11 DE DE8484115177T patent/DE3474510D1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0148436A1 (de) | 1985-07-17 |
| DE3474510D1 (en) | 1988-11-17 |
| EP0148436B1 (de) | 1988-10-12 |
| US4507289A (en) | 1985-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |