ATE346066T1 - Verwendung von benzo(c)chinoliziniumderivaten zur behandlung von krankheiten die durch verengungen der glatten muskelzellen bedingt sind - Google Patents

Verwendung von benzo(c)chinoliziniumderivaten zur behandlung von krankheiten die durch verengungen der glatten muskelzellen bedingt sind

Info

Publication number
ATE346066T1
ATE346066T1 AT03757110T AT03757110T ATE346066T1 AT E346066 T1 ATE346066 T1 AT E346066T1 AT 03757110 T AT03757110 T AT 03757110T AT 03757110 T AT03757110 T AT 03757110T AT E346066 T1 ATE346066 T1 AT E346066T1
Authority
AT
Austria
Prior art keywords
aromatic
optionally substituted
benzo
treatment
smooth muscle
Prior art date
Application number
AT03757110T
Other languages
English (en)
Inventor
Frederic Becq
Renaud Robert
Laurence Pignoux
Christian Rogier
Yvette Mettey
Jean Michel Vierfond
Michel Joffre
Cecile Marivingt-Mounir
Original Assignee
Centre Nat Rech Scient
Univ Poitiers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Univ Poitiers filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE346066T1 publication Critical patent/ATE346066T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C07D455/06—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
AT03757110T 2002-06-05 2003-06-05 Verwendung von benzo(c)chinoliziniumderivaten zur behandlung von krankheiten die durch verengungen der glatten muskelzellen bedingt sind ATE346066T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0206916A FR2840610B1 (fr) 2002-06-05 2002-06-05 UTILISATION DE DERIVES DES BENZO[c]QUINOLIZINIUMS POUR LE TRAITEMENT DES PATHOLOGIES LIEES AUX PHENOMENES DE CONSTRICTION DES CELLULES MUSCULAIRES LISSES

Publications (1)

Publication Number Publication Date
ATE346066T1 true ATE346066T1 (de) 2006-12-15

Family

ID=29558983

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03757110T ATE346066T1 (de) 2002-06-05 2003-06-05 Verwendung von benzo(c)chinoliziniumderivaten zur behandlung von krankheiten die durch verengungen der glatten muskelzellen bedingt sind

Country Status (7)

Country Link
US (1) US7897610B2 (de)
EP (1) EP1509520B1 (de)
AT (1) ATE346066T1 (de)
AU (1) AU2003255646A1 (de)
DE (1) DE60309864T2 (de)
FR (1) FR2840610B1 (de)
WO (1) WO2003104228A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751969B1 (fr) * 1996-08-01 1998-12-04 Centre Nat Rech Scient Composes activateurs du canal cftr, et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
EP1509520A1 (de) 2005-03-02
US20050176747A1 (en) 2005-08-11
FR2840610B1 (fr) 2008-04-04
DE60309864T2 (de) 2007-09-06
AU2003255646A1 (en) 2003-12-22
DE60309864D1 (de) 2007-01-04
FR2840610A1 (fr) 2003-12-12
US7897610B2 (en) 2011-03-01
AU2003255646A8 (en) 2003-12-22
WO2003104228A1 (fr) 2003-12-18
EP1509520B1 (de) 2006-11-22

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