ATE327258T1 - Monoklonaler antikörper, der spezifisch mit dem fas-liganden reagiert, und verfahren zu seiner herstellung - Google Patents
Monoklonaler antikörper, der spezifisch mit dem fas-liganden reagiert, und verfahren zu seiner herstellungInfo
- Publication number
- ATE327258T1 ATE327258T1 AT96906907T AT96906907T ATE327258T1 AT E327258 T1 ATE327258 T1 AT E327258T1 AT 96906907 T AT96906907 T AT 96906907T AT 96906907 T AT96906907 T AT 96906907T AT E327258 T1 ATE327258 T1 AT E327258T1
- Authority
- AT
- Austria
- Prior art keywords
- monoclonal antibody
- producing
- reacting specifically
- antibody reacting
- fas ligand
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8742095 | 1995-03-20 | ||
JP30349295 | 1995-10-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE327258T1 true ATE327258T1 (de) | 2006-06-15 |
Family
ID=26428696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96906907T ATE327258T1 (de) | 1995-03-20 | 1996-03-21 | Monoklonaler antikörper, der spezifisch mit dem fas-liganden reagiert, und verfahren zu seiner herstellung |
Country Status (8)
Country | Link |
---|---|
US (1) | US6946255B1 (de) |
EP (1) | EP0872488B1 (de) |
JP (1) | JP3451092B2 (de) |
AT (1) | ATE327258T1 (de) |
AU (1) | AU716731B2 (de) |
CA (1) | CA2215905A1 (de) |
DE (1) | DE69636170T2 (de) |
WO (1) | WO1996029350A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6114507A (en) * | 1995-06-30 | 2000-09-05 | Mochida Pharmaceutical Co., Ltd. | Anti-Fas ligand antibody and assay method using the anti-Fas ligand antibody |
US6096312A (en) * | 1995-06-30 | 2000-08-01 | Mochida Pharmaceutical Co., Ltd. | Agent for suppressing a reduction of CD4+ lymphocytes |
AU724856B2 (en) * | 1995-06-30 | 2000-10-05 | Mochida Pharmaceutical Co., Ltd. | Anti-Fas ligand antibody and assay method using the anti-Fas ligand antibody |
JPH09124509A (ja) * | 1995-10-27 | 1997-05-13 | Sumitomo Electric Ind Ltd | 肝炎治療剤 |
US6777540B1 (en) * | 1996-09-02 | 2004-08-17 | Ko Okumura | Humanized immunoglobulin reacting specifically with Fas ligand or active fragments thereof and region inducing apoptosis originating in Fas ligand |
JP2002530066A (ja) * | 1998-11-19 | 2002-09-17 | スミスクライン・ビーチャム・コーポレイション | Rhammアンタゴニスト抗体 |
AU2002328429A1 (en) * | 2002-09-04 | 2004-03-29 | Chugai Seiyaku Kabushiki Kaisha | CONSTRUCTION OF ANTIBODY USING MRL/lpr MOUSE |
JP5253325B2 (ja) * | 2002-09-04 | 2013-07-31 | 中外製薬株式会社 | MRL/lprマウスを用いた抗体の作製 |
CA2644855C (en) | 2006-03-09 | 2019-11-19 | Aethlon Medical, Inc. | Extracorporeal removal of microvesicular particles |
AU2007341631B9 (en) | 2006-12-28 | 2012-10-04 | Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts | Neutralization of CD95 activity blocks invasion of glioblastoma cells in vivo |
PT2231708E (pt) * | 2007-12-12 | 2015-07-30 | Pincell Srl | Remédios para pênfigo contendo anticorpos anti-ligando de faz |
WO2010006772A2 (en) * | 2008-07-14 | 2010-01-21 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Use of cd95 inhibitors for the treatment of inflammatory disorders |
EP2166358A1 (de) * | 2008-09-17 | 2010-03-24 | Fundacio Institut de Recerca de l'Hospital Universitari Vall d'Hebron | Differentialdiagnostisches Biomarker von einen Schlaganfall imitierenden Bedingungen und Verfahren zur Verwendung dieser |
PT2376536E (pt) | 2008-12-12 | 2015-05-11 | Pincell Srl | Remédios para pênfigo contendo anticorpos anti-ligando de faz |
EP3076179A1 (de) | 2015-03-30 | 2016-10-05 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Diagnose und behandlung von minderwertigen glioma |
JP6884785B2 (ja) * | 2015-09-23 | 2021-06-09 | アポジェニックス アーゲー | 抗cd95l抗体 |
CN113402601A (zh) * | 2021-06-09 | 2021-09-17 | 河南中泽生物工程有限公司 | 一种抗非洲猪瘟病毒p54蛋白单克隆抗体的制备方法及应用 |
WO2023099578A1 (en) | 2021-12-01 | 2023-06-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Neutralizing anti-cd95l monoclonal antibodies |
WO2023208990A1 (en) | 2022-04-26 | 2023-11-02 | F. Hoffmann-La Roche Ag | Combination therapy for the treatment of cancer comprising a fas axis antagonist and a t-reg cell depleting agent antagonist, |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4950588A (en) * | 1985-07-10 | 1990-08-21 | Molecular Diagnostics, Inc. | Prolonged enhanced chemiluminescence |
JPH08127594A (ja) * | 1993-11-10 | 1996-05-21 | Mochida Pharmaceut Co Ltd | Fas抗原に結合する新規蛋白質およびそれをコードするDNA |
JPH09508009A (ja) | 1994-01-07 | 1997-08-19 | イミュネックス・コーポレーション | Fas抗原を結合するリガンド |
DE4447484C2 (de) * | 1994-04-08 | 1997-07-17 | Deutsches Krebsforsch | Mittel zur Hemmung von Apoptose |
-
1996
- 1996-03-21 JP JP52829196A patent/JP3451092B2/ja not_active Expired - Fee Related
- 1996-03-21 AT AT96906907T patent/ATE327258T1/de not_active IP Right Cessation
- 1996-03-21 CA CA002215905A patent/CA2215905A1/en not_active Abandoned
- 1996-03-21 WO PCT/JP1996/000734 patent/WO1996029350A1/ja active IP Right Grant
- 1996-03-21 EP EP96906907A patent/EP0872488B1/de not_active Expired - Lifetime
- 1996-03-21 AU AU50141/96A patent/AU716731B2/en not_active Ceased
- 1996-03-21 US US08/913,555 patent/US6946255B1/en not_active Expired - Fee Related
- 1996-03-21 DE DE69636170T patent/DE69636170T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6946255B1 (en) | 2005-09-20 |
EP0872488A1 (de) | 1998-10-21 |
AU716731B2 (en) | 2000-03-02 |
EP0872488A4 (de) | 1999-05-19 |
DE69636170D1 (de) | 2006-06-29 |
JP3451092B2 (ja) | 2003-09-29 |
EP0872488B1 (de) | 2006-05-24 |
CA2215905A1 (en) | 1996-09-26 |
DE69636170T2 (de) | 2006-11-02 |
AU5014196A (en) | 1996-10-08 |
WO1996029350A1 (fr) | 1996-09-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |