ATE280953T1 - CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING OF TISSUE PERFUSION - Google Patents
CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING OF TISSUE PERFUSIONInfo
- Publication number
- ATE280953T1 ATE280953T1 AT98936548T AT98936548T ATE280953T1 AT E280953 T1 ATE280953 T1 AT E280953T1 AT 98936548 T AT98936548 T AT 98936548T AT 98936548 T AT98936548 T AT 98936548T AT E280953 T1 ATE280953 T1 AT E280953T1
- Authority
- AT
- Austria
- Prior art keywords
- contrast agent
- magnetic resonance
- resonance imaging
- tissue
- bolus
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
- G01R33/56341—Diffusion imaging
Abstract
This invention relates to a method of contrast agent-enhanced magnetic resonance imaging of perfusion in vasculated tissue within a human or non-human animal body in which a bolus comprising a contrast-enhancing amount of a magnetic resonance imaging contrast agent is administered into the vascular system of said body, and said body is subjected to a magnetic resonance imaging procedure whereby signals or images representative of first pass of said contrast agent bolus through tissue of interest are generated, characterised in that (i) said contrast agent is capable of exhibiting simultaneous, determinable T1 and T2* reducing effects under the imaging procedure employed and (ii) a T1-weighted imaging procedure is used (a) to visualise the first pass of said contrast agent bolus through said tissue by virtue of its signal lowering T2* effect and (b) to obtain a T1-weighted contrast agent-enhanced image of said tissue.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9716365.3A GB9716365D0 (en) | 1997-08-01 | 1997-08-01 | Improvements in or relating to magnetic resonance imaging |
PCT/GB1998/002281 WO1999006849A1 (en) | 1997-08-01 | 1998-07-30 | Contrast agent-enhanced magnetic resonance imaging of tissue perfusion |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE280953T1 true ATE280953T1 (en) | 2004-11-15 |
Family
ID=10816881
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98936548T ATE280953T1 (en) | 1997-08-01 | 1998-07-30 | CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING OF TISSUE PERFUSION |
Country Status (10)
Country | Link |
---|---|
US (1) | US6368574B1 (en) |
EP (1) | EP1000367B1 (en) |
JP (1) | JP4965020B2 (en) |
KR (1) | KR20010022471A (en) |
AT (1) | ATE280953T1 (en) |
AU (1) | AU8551498A (en) |
CA (1) | CA2296572A1 (en) |
DE (1) | DE69827263T2 (en) |
GB (1) | GB9716365D0 (en) |
WO (1) | WO1999006849A1 (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6295465B1 (en) * | 1999-02-17 | 2001-09-25 | Siemens Medical Systems, Inc. | Myocardial perfusion studies using magnetic resonance imaging |
EP1181570B1 (en) * | 1999-05-21 | 2006-11-22 | GE Healthcare AS | Method of magnetic resonance imaging |
GB9911939D0 (en) * | 1999-05-21 | 1999-07-21 | Nycomed Imaging As | Method |
WO2000072037A1 (en) * | 1999-05-21 | 2000-11-30 | Nycomed Imaging As | Method of magnetic resonance imaging |
US7082326B2 (en) | 2000-03-31 | 2006-07-25 | Amersham Health As | Method of magnetic resonance imaging |
WO2001074245A1 (en) * | 2000-03-31 | 2001-10-11 | Amersham Health As | Method of magnetic resonance imaging |
GB0007872D0 (en) * | 2000-03-31 | 2000-05-17 | Nycomed Imaging As | Method |
US6693426B1 (en) * | 2002-02-09 | 2004-02-17 | Intematix Corporation | Spatially resolved spin resonance detection |
US7106892B2 (en) * | 2002-09-19 | 2006-09-12 | Koninklijke Philips Electronics, N.V. | Display of image data information |
JP4890244B2 (en) * | 2003-07-01 | 2012-03-07 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Noninvasive quantitative myocardial perfusion assessment |
US7483732B2 (en) * | 2004-04-15 | 2009-01-27 | Boston Scientific Scimed, Inc. | Magnetic resonance imaging of a medical device and proximate body tissue |
GB2439747A (en) * | 2006-07-03 | 2008-01-09 | Uni Degli Studi Di Urbino Carl | Delivery of contrasting agents for magnetic resonance imaging |
MX2009004870A (en) * | 2006-11-02 | 2009-10-08 | Veridex Llc | Imaging of activated vascular endothelium using immunomagnetic mri contrast agents. |
AU2008254328A1 (en) | 2007-05-18 | 2008-11-27 | The Johns Hopkins University | A treatment simulator for brain diseases and method of use thereof |
US8580230B2 (en) * | 2009-02-23 | 2013-11-12 | Kent State University | Materials and methods for MRI contrast agents and drug delivery |
US10254367B2 (en) * | 2015-10-23 | 2019-04-09 | Siemens Healthcare Gmbh | Magnetic resonance imaging method and apparatus with motion-corrected model-based acceleration of parameter mapping |
KR101885998B1 (en) * | 2017-06-16 | 2018-08-06 | 가톨릭대학교 산학협력단 | Multiphase collateral imaging and perfusion imaging by postprocessing of 4-dimensional magnetic resonance angiography imaging information and medical systems thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1212629A (en) * | 1996-01-10 | 1999-03-31 | 耐克麦德英梅金公司 | Contrast media |
GB9600427D0 (en) * | 1996-01-10 | 1996-03-13 | Nycomed Imaging As | Contrast media |
-
1997
- 1997-08-01 GB GBGB9716365.3A patent/GB9716365D0/en active Pending
-
1998
- 1998-07-30 WO PCT/GB1998/002281 patent/WO1999006849A1/en active IP Right Grant
- 1998-07-30 CA CA002296572A patent/CA2296572A1/en not_active Abandoned
- 1998-07-30 EP EP98936548A patent/EP1000367B1/en not_active Expired - Lifetime
- 1998-07-30 AT AT98936548T patent/ATE280953T1/en not_active IP Right Cessation
- 1998-07-30 DE DE69827263T patent/DE69827263T2/en not_active Expired - Lifetime
- 1998-07-30 KR KR1020007001056A patent/KR20010022471A/en not_active Application Discontinuation
- 1998-07-30 JP JP2000505525A patent/JP4965020B2/en not_active Expired - Lifetime
- 1998-07-30 AU AU85514/98A patent/AU8551498A/en not_active Abandoned
-
2000
- 2000-01-21 US US09/488,785 patent/US6368574B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6368574B1 (en) | 2002-04-09 |
WO1999006849A1 (en) | 1999-02-11 |
DE69827263T2 (en) | 2006-02-02 |
JP4965020B2 (en) | 2012-07-04 |
EP1000367B1 (en) | 2004-10-27 |
EP1000367A1 (en) | 2000-05-17 |
GB9716365D0 (en) | 1997-10-08 |
AU8551498A (en) | 1999-02-22 |
CA2296572A1 (en) | 1999-02-11 |
JP2001512144A (en) | 2001-08-21 |
DE69827263D1 (en) | 2004-12-02 |
KR20010022471A (en) | 2001-03-15 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |