ATE239497T1 - Verwendung von urodilatin zur behandlung chronischer niereninsuffizienz mit nierenrestfunktionen - Google Patents
Verwendung von urodilatin zur behandlung chronischer niereninsuffizienz mit nierenrestfunktionenInfo
- Publication number
- ATE239497T1 ATE239497T1 AT00975905T AT00975905T ATE239497T1 AT E239497 T1 ATE239497 T1 AT E239497T1 AT 00975905 T AT00975905 T AT 00975905T AT 00975905 T AT00975905 T AT 00975905T AT E239497 T1 ATE239497 T1 AT E239497T1
- Authority
- AT
- Austria
- Prior art keywords
- urodilatin
- residual
- treat chronic
- insufficiency
- renal function
- Prior art date
Links
- 108010001957 Ularitide Proteins 0.000 title abstract 2
- 102400001279 Urodilatin Human genes 0.000 title abstract 2
- 208000020832 chronic kidney disease Diseases 0.000 title abstract 2
- 230000003907 kidney function Effects 0.000 title abstract 2
- KICHBVZYZBOCOQ-TYLLENITSA-N acetic acid (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(4R,10S,16S,19S,22S,28S,31S,34S,37S,40S,49S,52R)-52-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-19-(3-amino-3-oxopropyl)-49-benzyl-28-[(2S)-butan-2-yl]-31,40-bis(3-carbamimidamidopropyl)-34-(carboxymethyl)-16-(hydroxymethyl)-22-methyl-10-(2-methylpropyl)-37-(2-methylsulfanylethyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51-hexadecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecazacyclotripentacontane-4-carbonyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid Chemical compound CC(O)=O.CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)CNC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@@H](N)[C@@H](C)O KICHBVZYZBOCOQ-TYLLENITSA-N 0.000 title 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- IUCCYQIEZNQWRS-DWWHXVEHSA-N ularitide Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(O)=O)=O)[C@@H](C)CC)C1=CC=CC=C1 IUCCYQIEZNQWRS-DWWHXVEHSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19951471A DE19951471A1 (de) | 1999-10-26 | 1999-10-26 | Verwendung von Urodilatin zur Behandlung chronischer Niereninsuffizienz mit Nierenrestfunktionen |
| PCT/EP2000/010462 WO2001030376A2 (de) | 1999-10-26 | 2000-10-24 | Verwendung von urodilatin zur behandlung chronischer niereninsuffizienz mit nierenrestfunktionen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239497T1 true ATE239497T1 (de) | 2003-05-15 |
Family
ID=7926884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00975905T ATE239497T1 (de) | 1999-10-26 | 2000-10-24 | Verwendung von urodilatin zur behandlung chronischer niereninsuffizienz mit nierenrestfunktionen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6831064B1 (enExample) |
| EP (1) | EP1223968B1 (enExample) |
| JP (1) | JP2003512434A (enExample) |
| AT (1) | ATE239497T1 (enExample) |
| DE (2) | DE19951471A1 (enExample) |
| ES (1) | ES2198359T3 (enExample) |
| WO (1) | WO2001030376A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006110743A1 (en) | 2005-04-07 | 2006-10-19 | Cardiopep Pharma Gmbh | Use of natriuretic peptide for treating heart failure |
| US20080181903A1 (en) * | 2006-12-21 | 2008-07-31 | Pdl Biopharma, Inc. | Conjugate of natriuretic peptide and antibody constant region |
| WO2009034134A2 (en) * | 2007-09-11 | 2009-03-19 | Pharis Biotec Gmbh | Use of natriuretic peptides for treating angioedema syndromes |
| EP2078530A1 (en) | 2008-01-08 | 2009-07-15 | Pharis Biotec GmbH | Use of natriuretic peptides for treating angioedema syndromes |
| WO2010033240A2 (en) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
| EP2948165A2 (en) | 2013-01-25 | 2015-12-02 | Cardiorentis Ltd. | A natriuretic peptide, a diuretic peptide or a vasodilatory peptide for use in methods of treating cardiovascular indications |
| WO2022029499A1 (en) | 2020-08-06 | 2022-02-10 | Ads Aiphia Development Services Ag | Methods of treating refractory ascites |
| WO2022029497A1 (en) | 2020-08-06 | 2022-02-10 | Ads Aiphia Development Services Ag | Ularitide for use in methods of treating refractory ascites |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988006596A1 (en) | 1987-03-02 | 1988-09-07 | Bissendorf Peptide Gmbh | New cardiodilatin fragment, process for preparing same and use thereof |
| US5691310A (en) * | 1987-09-29 | 1997-11-25 | Vesely; David L. | Methods of treatment using proANF peptides |
| DE4216133A1 (de) * | 1992-05-15 | 1993-11-18 | Bissendorf Peptide Gmbh | Anwendung von Urodilatin bei Lungen- und Bronchialerkrankungen |
| US5565428A (en) * | 1995-05-22 | 1996-10-15 | Genentech, Inc. | Method of administration of IGF-I |
| US5741776A (en) * | 1995-05-22 | 1998-04-21 | Genentech, Inc. | Method of administration of IGF-I |
| SI20151A (sl) * | 1996-12-31 | 2000-08-31 | Ajay Gupta | Metode in farmacevtske zmesi za aplikacijo železa hemodializnim in peritonealno dializnim pacientom |
-
1999
- 1999-10-26 DE DE19951471A patent/DE19951471A1/de not_active Withdrawn
-
2000
- 2000-10-24 JP JP2001532793A patent/JP2003512434A/ja active Pending
- 2000-10-24 DE DE50002119T patent/DE50002119D1/de not_active Expired - Lifetime
- 2000-10-24 AT AT00975905T patent/ATE239497T1/de not_active IP Right Cessation
- 2000-10-24 WO PCT/EP2000/010462 patent/WO2001030376A2/de not_active Ceased
- 2000-10-24 EP EP00975905A patent/EP1223968B1/de not_active Expired - Lifetime
- 2000-10-24 ES ES00975905T patent/ES2198359T3/es not_active Expired - Lifetime
- 2000-10-24 US US10/088,498 patent/US6831064B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1223968A2 (de) | 2002-07-24 |
| DE50002119D1 (de) | 2003-06-12 |
| WO2001030376A2 (de) | 2001-05-03 |
| US6831064B1 (en) | 2004-12-14 |
| EP1223968B1 (de) | 2003-05-07 |
| DE19951471A1 (de) | 2001-05-03 |
| ES2198359T3 (es) | 2004-02-01 |
| JP2003512434A (ja) | 2003-04-02 |
| WO2001030376A3 (de) | 2001-12-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |