ATE237366T1 - Radioaktiv-markierte annexine - Google Patents
Radioaktiv-markierte annexineInfo
- Publication number
- ATE237366T1 ATE237366T1 AT95913955T AT95913955T ATE237366T1 AT E237366 T1 ATE237366 T1 AT E237366T1 AT 95913955 T AT95913955 T AT 95913955T AT 95913955 T AT95913955 T AT 95913955T AT E237366 T1 ATE237366 T1 AT E237366T1
- Authority
- AT
- Austria
- Prior art keywords
- radioactive labeled
- annexins
- labeled annexins
- radioactive
- radiolabeled annexins
- Prior art date
Links
- 102000000412 Annexin Human genes 0.000 title abstract 3
- 108050008874 Annexin Proteins 0.000 title abstract 3
- 230000002285 radioactive effect Effects 0.000 title 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/547—Chelates, e.g. Gd-DOTA or Zinc-amino acid chelates; Chelate-forming compounds, e.g. DOTA or ethylenediamine being covalently linked or complexed to the pharmacologically- or therapeutically-active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/087—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being an annexin, e.g. annexin V
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
- Lubricants (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18566094A | 1994-01-24 | 1994-01-24 | |
| PCT/US1995/000953 WO1995019791A1 (en) | 1994-01-24 | 1995-01-23 | Radiolabeled annexins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE237366T1 true ATE237366T1 (de) | 2003-05-15 |
Family
ID=22681925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95913955T ATE237366T1 (de) | 1994-01-24 | 1995-01-23 | Radioaktiv-markierte annexine |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0743861B1 (de) |
| JP (1) | JP3664727B2 (de) |
| AT (1) | ATE237366T1 (de) |
| CA (1) | CA2180555C (de) |
| DE (1) | DE69530375T2 (de) |
| WO (1) | WO1995019791A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19505960A1 (de) * | 1995-02-21 | 1996-08-22 | Deutsches Krebsforsch | Konjugat zur individuellen Dosierung von Arzneimitteln |
| DE19536783A1 (de) * | 1995-09-21 | 1997-03-27 | Diagnostikforschung Inst | Bifunktionelle Nicotinamid-Chelatbildner vom Typ N¶2¶S¶2¶ für radioaktive Isotope |
| CA2331789C (en) | 1998-07-13 | 2013-09-10 | Board Of Regents, The University Of Texas System | Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids |
| US6818213B1 (en) | 1998-07-13 | 2004-11-16 | Board Of Regents, The University Of Texas System | Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids |
| US6406693B1 (en) | 1998-07-13 | 2002-06-18 | Board Of Regents, The University Of Texas System | Cancer treatment methods using antibodies to aminophospholipids |
| EP2311490A3 (de) | 1998-07-13 | 2011-05-04 | Board of Regents, The University of Texas System | Verwendung von Antikörper gegen Aminophospholipide zur Krebsbehandlung |
| US6323313B1 (en) | 1999-06-01 | 2001-11-27 | The University Of Washington | Annexin derivative with endogenous chelation sites |
| EP1381839A4 (de) * | 2001-04-03 | 2005-10-12 | Univ Leland Stanford Junior | Verfahren zur bildlichen darstellung von zelltod in vivo |
| JP5855003B2 (ja) * | 2010-09-01 | 2016-02-09 | 国立大学法人京都大学 | 血液凝固調節物質のスクリーニング方法 |
| ES2863278T3 (es) * | 2015-10-02 | 2021-10-11 | Silver Creek Pharmaceuticals Inc | Proteínas terapéuticas biespecíficas para la reparación de tejidos |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4897255A (en) * | 1985-01-14 | 1990-01-30 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
| EP0409053B1 (de) * | 1989-07-15 | 1993-09-29 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Verfahren zur Reinigung von Annexinen |
| DE3937607A1 (de) * | 1989-11-11 | 1991-05-16 | Boehringer Ingelheim Int | Verwendung eines antikoagulanz zur behandlung von tumorerkrankungen |
| US5627036A (en) * | 1989-12-27 | 1997-05-06 | Boehringer Ingelheim International Gmbh | Use of an anticoagulant as a diagnostic agent |
| EP0806670B1 (de) * | 1989-12-27 | 2009-04-22 | Boehringer Ingelheim International GmbH | Verwendung eines Antikoagulant als Diagnostikum |
| WO1992019279A1 (en) * | 1991-05-09 | 1992-11-12 | Board Of Regents Of The University Of Washington | Phospholipid-targeted thrombolytic agents |
| JPH10504534A (ja) * | 1994-06-16 | 1998-05-06 | ネオルクス コーポレイション | 放射性標識アネキシン−ガラクトース結合体 |
| US5886143A (en) * | 1994-12-07 | 1999-03-23 | Neorx Corporation | Hepatic-directed compounds and reagents for preparation thereof |
| CA2206274C (en) * | 1994-12-07 | 2009-06-30 | Neorx Corporation | Radiolabeled annexin-galactose cluster conjugates |
-
1995
- 1995-01-23 AT AT95913955T patent/ATE237366T1/de not_active IP Right Cessation
- 1995-01-23 WO PCT/US1995/000953 patent/WO1995019791A1/en not_active Ceased
- 1995-01-23 EP EP95913955A patent/EP0743861B1/de not_active Expired - Lifetime
- 1995-01-23 JP JP51973495A patent/JP3664727B2/ja not_active Expired - Fee Related
- 1995-01-23 DE DE69530375T patent/DE69530375T2/de not_active Expired - Lifetime
- 1995-01-23 CA CA002180555A patent/CA2180555C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0743861A4 (de) | 1999-03-31 |
| CA2180555C (en) | 2004-12-14 |
| EP0743861B1 (de) | 2003-04-16 |
| CA2180555A1 (en) | 1995-07-27 |
| EP0743861A1 (de) | 1996-11-27 |
| JPH09509050A (ja) | 1997-09-16 |
| DE69530375T2 (de) | 2004-02-05 |
| WO1995019791A1 (en) | 1995-07-27 |
| JP3664727B2 (ja) | 2005-06-29 |
| DE69530375D1 (de) | 2003-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |