ATE228004T1 - USE OF RELAXIN TO STIMULATE ANGIOGENesis - Google Patents
USE OF RELAXIN TO STIMULATE ANGIOGENesisInfo
- Publication number
- ATE228004T1 ATE228004T1 AT96928212T AT96928212T ATE228004T1 AT E228004 T1 ATE228004 T1 AT E228004T1 AT 96928212 T AT96928212 T AT 96928212T AT 96928212 T AT96928212 T AT 96928212T AT E228004 T1 ATE228004 T1 AT E228004T1
- Authority
- AT
- Austria
- Prior art keywords
- relaxin
- stimulate angiogenesis
- angiogenesis
- infections
- lack
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2221—Relaxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Surgery (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Relaxin is useful for promoting angiogenesis and the treatment of infections or ischemic wounds where the injury results from lack of oxygen due to poor circulation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US235595P | 1995-08-15 | 1995-08-15 | |
PCT/US1996/013321 WO1997006814A1 (en) | 1995-08-15 | 1996-08-15 | Method of promoting angiogenesis |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE228004T1 true ATE228004T1 (en) | 2002-12-15 |
Family
ID=21700396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96928212T ATE228004T1 (en) | 1995-08-15 | 1996-08-15 | USE OF RELAXIN TO STIMULATE ANGIOGENesis |
Country Status (9)
Country | Link |
---|---|
US (3) | US6211147B1 (en) |
EP (1) | EP0845992B1 (en) |
JP (1) | JP4568383B2 (en) |
AT (1) | ATE228004T1 (en) |
AU (1) | AU6777196A (en) |
CA (1) | CA2229479C (en) |
DE (1) | DE69624925T2 (en) |
ES (1) | ES2187667T3 (en) |
WO (1) | WO1997006814A1 (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1253929B1 (en) * | 2000-02-09 | 2007-05-23 | BAS Medical, Inc. | Use of relaxin to treat diseases related to vasoconstriction |
ITRM20020119A1 (en) * | 2002-03-05 | 2003-09-05 | Geymonat Spa | COMPOSITIONS CONTAINING PLGF FOR PHARMACEUTICAL AND COSMETIC USE. |
US7878978B2 (en) * | 2004-03-18 | 2011-02-01 | University Of Pittsburgh- Of The Commonwealth System Of Higher Education | Use of relaxin to increase arterial compliance |
EP1765149B1 (en) * | 2004-03-19 | 2016-09-28 | University Of Pittsburgh | Use of relaxin to increase arterial compliance |
CA2563433C (en) * | 2004-04-30 | 2010-07-13 | Bas Medical, Inc. | Methods and compositions for control of fetal growth via modulation of relaxin |
US7893244B2 (en) * | 2005-04-12 | 2011-02-22 | Intradigm Corporation | Composition and methods of RNAi therapeutics for treatment of cancer and other neovascularization diseases |
CN101277704A (en) * | 2005-04-12 | 2008-10-01 | 因特拉迪格姆公司 | Composition and methods of rnai therapeutics for treatment of cancer and other neovascularization diseases |
US20060281669A1 (en) * | 2005-06-13 | 2006-12-14 | Yue Samuel K | Method and compositions for the treatment of diabetes and related complications |
US8496446B2 (en) * | 2005-08-29 | 2013-07-30 | Carrier Corporation | Compressor muffler |
US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
CN102026650A (en) * | 2008-05-16 | 2011-04-20 | 科尔泰拉公司 | Method of preventing premature delivery |
CA2724540C (en) | 2008-05-16 | 2014-07-08 | Corthera, Inc. | Treating dyspnea associated with acute heart failure with relaxin |
WO2009140433A1 (en) * | 2008-05-16 | 2009-11-19 | Corthera, Inc. | Method of promoting wound healing |
BRPI0805852A8 (en) * | 2008-09-05 | 2021-06-29 | Univ Rio De Janeiro | protein acid polymers, production processes, use of protein acid polymers, pharmaceutical composition and treatment method |
US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
WO2010033878A2 (en) | 2008-09-19 | 2010-03-25 | David Brown | Solute concentration measurement device and related methods |
WO2011014704A2 (en) | 2009-07-30 | 2011-02-03 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
ES2972902T3 (en) | 2010-08-17 | 2024-06-17 | Ambrx Inc | Modified relaxin polypeptides and their uses |
WO2013033324A2 (en) * | 2011-08-31 | 2013-03-07 | University Of Florida Research Foundation, Inc. | Materials and methods for modulating activity of bone marrow derived cells |
US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
US9555186B2 (en) | 2012-06-05 | 2017-01-31 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
US9526762B1 (en) * | 2013-08-09 | 2016-12-27 | William Marsh Rice University | Multidomain peptides for promoting angiogenesis |
EP4011919A3 (en) | 2015-12-09 | 2022-10-12 | The Scripps Research Institute | Relaxin immunoglobulin fusion proteins and methods of use |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5023321A (en) | 1982-12-13 | 1991-06-11 | Howard Florey Institute Of Experimental Physiology & Medicine | Molecular cloning and characterization of a further gene sequence coding for human relaxin |
US5023088A (en) * | 1987-06-25 | 1991-06-11 | Alza Corporation | Multi-unit delivery system |
WO1989007945A1 (en) * | 1988-02-26 | 1989-09-08 | Genentech, Inc. | Human relaxin formulation |
GB8907799D0 (en) * | 1989-04-06 | 1989-05-17 | Erba Carlo Spa | Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases |
JP2857684B2 (en) | 1989-05-04 | 1999-02-17 | ジェネンテク,インコーポレイテッド | Methods and compositions for the isolation of human relaxin |
US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
US5166191A (en) * | 1991-08-19 | 1992-11-24 | Genentech, Inc. | Use of relaxin in cardiovascular therapy |
US5478807A (en) | 1991-08-19 | 1995-12-26 | Genentech, Inc. | Use of relaxin in the treatment of bradycardia |
WO1995003822A2 (en) * | 1993-07-27 | 1995-02-09 | Mario Bigazzi | Use of relaxin as therapeutic or preventing agent |
US5811395A (en) * | 1995-06-07 | 1998-09-22 | Medical University Of South Carolina | Relaxin analogs and derivatives methods and uses thereof |
US5911997A (en) * | 1995-06-07 | 1999-06-15 | Connetics Corporation | Relaxin-like factor and methods and uses thereof |
US5753623A (en) * | 1995-06-07 | 1998-05-19 | Connetics Corporation | Method of treatment for depression |
-
1996
- 1996-08-15 CA CA2229479A patent/CA2229479C/en not_active Expired - Lifetime
- 1996-08-15 ES ES96928212T patent/ES2187667T3/en not_active Expired - Lifetime
- 1996-08-15 AT AT96928212T patent/ATE228004T1/en active
- 1996-08-15 DE DE69624925T patent/DE69624925T2/en not_active Expired - Lifetime
- 1996-08-15 EP EP96928212A patent/EP0845992B1/en not_active Expired - Lifetime
- 1996-08-15 WO PCT/US1996/013321 patent/WO1997006814A1/en active IP Right Grant
- 1996-08-15 JP JP50951597A patent/JP4568383B2/en not_active Expired - Lifetime
- 1996-08-15 US US08/698,359 patent/US6211147B1/en not_active Expired - Lifetime
- 1996-08-15 AU AU67771/96A patent/AU6777196A/en not_active Abandoned
-
2001
- 2001-02-08 US US09/780,758 patent/US6780836B2/en not_active Expired - Lifetime
-
2004
- 2004-04-05 US US10/818,859 patent/US20040192606A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2229479A1 (en) | 1997-02-27 |
JPH11511174A (en) | 1999-09-28 |
DE69624925T2 (en) | 2003-09-04 |
WO1997006814A1 (en) | 1997-02-27 |
EP0845992B1 (en) | 2002-11-20 |
CA2229479C (en) | 2010-03-30 |
EP0845992A4 (en) | 2000-04-19 |
AU6777196A (en) | 1997-03-12 |
JP4568383B2 (en) | 2010-10-27 |
US20010018418A1 (en) | 2001-08-30 |
DE69624925D1 (en) | 2003-01-02 |
US6211147B1 (en) | 2001-04-03 |
US20040192606A1 (en) | 2004-09-30 |
EP0845992A1 (en) | 1998-06-10 |
ES2187667T3 (en) | 2003-06-16 |
US6780836B2 (en) | 2004-08-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
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