ATE223405T1 - MODIFIED FORM OF THE HYDROCHLORIDE OF R(-)-N-(4,4-DI(-3-METHYLTHIEN-2-YL)BUT-3-ENYL)-NIPECOTIC ACID - Google Patents

MODIFIED FORM OF THE HYDROCHLORIDE OF R(-)-N-(4,4-DI(-3-METHYLTHIEN-2-YL)BUT-3-ENYL)-NIPECOTIC ACID

Info

Publication number
ATE223405T1
ATE223405T1 AT97927006T AT97927006T ATE223405T1 AT E223405 T1 ATE223405 T1 AT E223405T1 AT 97927006 T AT97927006 T AT 97927006T AT 97927006 T AT97927006 T AT 97927006T AT E223405 T1 ATE223405 T1 AT E223405T1
Authority
AT
Austria
Prior art keywords
methylthien
enyl
hydrochloride
modified form
nipecotic acid
Prior art date
Application number
AT97927006T
Other languages
German (de)
Inventor
Preben Ahrndt
Henning Borge Petersen
Vincent H Chang
Kimberly Ann Allen
Michael H Chain
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE223405T1 publication Critical patent/ATE223405T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT97927006T 1996-06-14 1997-06-03 MODIFIED FORM OF THE HYDROCHLORIDE OF R(-)-N-(4,4-DI(-3-METHYLTHIEN-2-YL)BUT-3-ENYL)-NIPECOTIC ACID ATE223405T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK66196 1996-06-14
PCT/DK1997/000244 WO1997047619A1 (en) 1996-06-14 1997-06-03 Modified form of the r(-)-n-(4,4-di(3-methylthien-2-yl)but-3-enyl)-nipecotic acid hydrochloride

Publications (1)

Publication Number Publication Date
ATE223405T1 true ATE223405T1 (en) 2002-09-15

Family

ID=8096101

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97927006T ATE223405T1 (en) 1996-06-14 1997-06-03 MODIFIED FORM OF THE HYDROCHLORIDE OF R(-)-N-(4,4-DI(-3-METHYLTHIEN-2-YL)BUT-3-ENYL)-NIPECOTIC ACID

Country Status (20)

Country Link
EP (1) EP0906309B1 (en)
JP (1) JP2000511909A (en)
CN (1) CN1636565A (en)
AR (1) AR008236A1 (en)
AT (1) ATE223405T1 (en)
AU (1) AU723267B2 (en)
BR (1) BR9709725A (en)
CZ (1) CZ295578B6 (en)
DE (1) DE69715196T2 (en)
DK (1) DK0906309T3 (en)
ES (1) ES2181002T3 (en)
HU (1) HUP9904035A3 (en)
IL (1) IL127469A (en)
NO (1) NO316889B1 (en)
PL (1) PL190858B1 (en)
PT (1) PT906309E (en)
RU (1) RU2177478C2 (en)
UA (1) UA52661C2 (en)
WO (1) WO1997047619A1 (en)
ZA (1) ZA975266B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914333A (en) * 1996-07-31 1999-06-22 Novo Nordisk A/S Treatment of psychotic disorders
IE970588A1 (en) 1997-08-01 2000-08-23 Elan Corp Plc Controlled release pharmaceutical compositions containing tiagabine
ATE212550T1 (en) * 1997-08-01 2002-02-15 Elan Corp Plc MEDICINAL PREPARATIONS CONTAINING TIAGABINE WITH CONTROLLED ADMINISTRATION OF ACTIVE INGREDIENTS
CN1314684C (en) * 2003-12-24 2007-05-09 中国科学院上海有机化学研究所 Synthesis method of saijiabin, its racemate and S-configuration, and preparation method of its amorphous powder
GB0402118D0 (en) * 2004-01-30 2004-03-03 Merck Sharp & Dohme Polymorphic forms of a GABAA agonist
WO2005092886A1 (en) * 2004-03-29 2005-10-06 Ranbaxy Laboratories Limited Process for the preparation of amorphous form of tiagabine
US20080064727A1 (en) * 2006-08-18 2008-03-13 Cephalon, Inc. Crystalline forms of tiagabine hydrochloride

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK288385D0 (en) * 1985-06-26 1985-06-26 Novo Industri As AMINO ACID DERIVATIVES
DK58291D0 (en) * 1991-04-02 1991-04-02 Novo Nordisk As CRYSTALINE MATERIAL AND ITS PREPARATION

Also Published As

Publication number Publication date
CZ401998A3 (en) 1999-06-16
DE69715196T2 (en) 2003-05-15
PL190858B1 (en) 2006-02-28
NO985809L (en) 1998-12-11
JP2000511909A (en) 2000-09-12
CN1636565A (en) 2005-07-13
AU723267B2 (en) 2000-08-24
NO985809D0 (en) 1998-12-11
PT906309E (en) 2002-12-31
UA52661C2 (en) 2003-01-15
BR9709725A (en) 1999-08-10
NO316889B1 (en) 2004-06-14
HUP9904035A3 (en) 2000-07-28
WO1997047619A1 (en) 1997-12-18
PL330424A1 (en) 1999-05-10
AR008236A1 (en) 1999-12-29
CZ295578B6 (en) 2005-08-17
IL127469A (en) 2001-01-11
DE69715196D1 (en) 2002-10-10
AU3165397A (en) 1998-01-07
EP0906309A1 (en) 1999-04-07
IL127469A0 (en) 1999-10-28
RU2177478C2 (en) 2001-12-27
EP0906309B1 (en) 2002-09-04
HUP9904035A2 (en) 2000-05-28
ZA975266B (en) 1998-02-04
ES2181002T3 (en) 2003-02-16
DK0906309T3 (en) 2002-12-16

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