ATE221079T1 - Zusammensetzungen und verfahrenen zur synthese von organophosphorus derivaten - Google Patents
Zusammensetzungen und verfahrenen zur synthese von organophosphorus derivatenInfo
- Publication number
- ATE221079T1 ATE221079T1 AT96927149T AT96927149T ATE221079T1 AT E221079 T1 ATE221079 T1 AT E221079T1 AT 96927149 T AT96927149 T AT 96927149T AT 96927149 T AT96927149 T AT 96927149T AT E221079 T1 ATE221079 T1 AT E221079T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- synthesis
- compositions
- nucleoside
- chirality
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL31024895A PL181746B1 (pl) | 1995-09-01 | 1995-09-01 | Sposób wytwarzania modyfikowanych P-chiralnych analogów nukleotydów |
PL96312934A PL184377B1 (pl) | 1996-02-26 | 1996-02-26 | Nowe pochodne fosforoorganiczne i sposób ich wytwarzania |
US08/653,204 US5936080A (en) | 1996-05-24 | 1996-05-24 | Compositions and methods for the synthesis of organophosphorus derivatives |
PCT/IB1996/000867 WO1997009340A1 (en) | 1995-09-01 | 1996-08-29 | Compositions and methods for the synthesis of organophosphorus derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE221079T1 true ATE221079T1 (de) | 2002-08-15 |
Family
ID=27354079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96927149T ATE221079T1 (de) | 1995-09-01 | 1996-08-29 | Zusammensetzungen und verfahrenen zur synthese von organophosphorus derivaten |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0850248B1 (de) |
AT (1) | ATE221079T1 (de) |
AU (1) | AU707093B2 (de) |
CA (1) | CA2233460A1 (de) |
DE (1) | DE69622571T2 (de) |
DK (1) | DK0850248T3 (de) |
NZ (1) | NZ315384A (de) |
WO (1) | WO1997009340A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5852188A (en) | 1990-01-11 | 1998-12-22 | Isis Pharmaceuticals, Inc. | Oligonucleotides having chiral phosphorus linkages |
ATE221127T1 (de) | 1991-10-15 | 2002-08-15 | Isis Pharmaceuticals Inc | Über chirale phosphoratome gebundene oligonukleotide |
ATE245161T1 (de) * | 1995-05-26 | 2003-08-15 | Genta Inc | Verfahren zur synthese von phosphororganischen verbindungen |
US6211354B1 (en) * | 1998-05-06 | 2001-04-03 | Tosch Corporation | Optically active DNA probe having phosphonic diester linkage |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991004983A1 (en) * | 1989-10-05 | 1991-04-18 | University Patents, Inc. | Nucleoside and polynucleotide thiophosphoramidite and phosphorodithioate compounds and processes |
US5703223A (en) * | 1994-09-02 | 1997-12-30 | Thomas Jefferson University | Solid phase synthesis of oligonucleotides with stereospecific substituted phosphonate linkages by pentavalent grignard coupling |
-
1996
- 1996-08-29 WO PCT/IB1996/000867 patent/WO1997009340A1/en active IP Right Grant
- 1996-08-29 DK DK96927149T patent/DK0850248T3/da active
- 1996-08-29 CA CA002233460A patent/CA2233460A1/en not_active Abandoned
- 1996-08-29 EP EP96927149A patent/EP0850248B1/de not_active Expired - Lifetime
- 1996-08-29 DE DE69622571T patent/DE69622571T2/de not_active Expired - Fee Related
- 1996-08-29 NZ NZ315384A patent/NZ315384A/en unknown
- 1996-08-29 AT AT96927149T patent/ATE221079T1/de not_active IP Right Cessation
- 1996-08-29 AU AU67079/96A patent/AU707093B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP0850248B1 (de) | 2002-07-24 |
CA2233460A1 (en) | 1997-03-13 |
WO1997009340A1 (en) | 1997-03-13 |
NZ315384A (en) | 1999-04-29 |
DE69622571T2 (de) | 2003-03-27 |
AU6707996A (en) | 1997-03-27 |
DE69622571D1 (de) | 2002-08-29 |
EP0850248A1 (de) | 1998-07-01 |
AU707093B2 (en) | 1999-07-01 |
DK0850248T3 (da) | 2002-11-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0850248 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |