ATE216591T1 - COMBINATION THERAPY CONTAINING RIBAVIRIN AND INTERFERON ALPHA IN PATIENTS WITH CHRONIC HEPATITIS C INFECTION WHO ARE NOT PREVIOUSLY TREATED WITH ANTIVIRALS - Google Patents

COMBINATION THERAPY CONTAINING RIBAVIRIN AND INTERFERON ALPHA IN PATIENTS WITH CHRONIC HEPATITIS C INFECTION WHO ARE NOT PREVIOUSLY TREATED WITH ANTIVIRALS

Info

Publication number
ATE216591T1
ATE216591T1 AT99303729T AT99303729T ATE216591T1 AT E216591 T1 ATE216591 T1 AT E216591T1 AT 99303729 T AT99303729 T AT 99303729T AT 99303729 T AT99303729 T AT 99303729T AT E216591 T1 ATE216591 T1 AT E216591T1
Authority
AT
Austria
Prior art keywords
antivirals
infection
patients
combination therapy
interferon alpha
Prior art date
Application number
AT99303729T
Other languages
German (de)
Inventor
Janice K Albrecht
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22151354&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE216591(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE216591T1 publication Critical patent/ATE216591T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AT99303729T 1998-05-15 1999-05-13 COMBINATION THERAPY CONTAINING RIBAVIRIN AND INTERFERON ALPHA IN PATIENTS WITH CHRONIC HEPATITIS C INFECTION WHO ARE NOT PREVIOUSLY TREATED WITH ANTIVIRALS ATE216591T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7956698A 1998-05-15 1998-05-15

Publications (1)

Publication Number Publication Date
ATE216591T1 true ATE216591T1 (en) 2002-05-15

Family

ID=22151354

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99303729T ATE216591T1 (en) 1998-05-15 1999-05-13 COMBINATION THERAPY CONTAINING RIBAVIRIN AND INTERFERON ALPHA IN PATIENTS WITH CHRONIC HEPATITIS C INFECTION WHO ARE NOT PREVIOUSLY TREATED WITH ANTIVIRALS

Country Status (23)

Country Link
EP (3) EP0956861B1 (en)
JP (2) JP5281726B2 (en)
KR (1) KR100694345B1 (en)
CN (1) CN1230198C (en)
AR (1) AR019551A1 (en)
AT (1) ATE216591T1 (en)
AU (2) AU766597B2 (en)
BR (1) BR9910505A (en)
CA (1) CA2331823A1 (en)
CZ (1) CZ300540B6 (en)
DE (1) DE69901321T2 (en)
DK (1) DK0956861T3 (en)
ES (1) ES2172288T3 (en)
HK (1) HK1021131A1 (en)
HU (1) HU230432B1 (en)
IL (3) IL139220A0 (en)
MY (1) MY129244A (en)
NO (1) NO330715B1 (en)
NZ (1) NZ507621A (en)
PT (1) PT956861E (en)
SK (1) SK288038B6 (en)
TW (1) TWI277424B (en)
WO (1) WO1999059621A1 (en)

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JP4536194B2 (en) * 2000-02-17 2010-09-01 大日本住友製薬株式会社 Stable injectable formulation
AU2001259063A1 (en) 2000-04-12 2001-10-30 Human Genome Sciences, Inc. Albumin fusion proteins
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
KR20030036189A (en) 2000-05-26 2003-05-09 이데닉스(케이만)리미티드 Methods and compositions for treating flaviviruses and pestiviruses
WO2002032414A2 (en) * 2000-10-18 2002-04-25 Schering Corporation Ribavirin-pegylated interferon alfa hcv combination therapy
EP1536839B1 (en) * 2001-11-09 2010-09-15 Intarcia Therapeutics, Inc Combination therapy comprising omega-interferon for treating infection with hepatitis c virus or yellow fever virus
EP1463751B1 (en) 2001-12-21 2013-05-22 Human Genome Sciences, Inc. Albumin fusion proteins
US7608600B2 (en) 2002-06-28 2009-10-27 Idenix Pharmaceuticals, Inc. Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
DE14169110T1 (en) 2002-06-28 2022-05-12 Centre National De La Recherche Scientifique -Cnrs- Modified 2' and 3' nucleoside prodrugs for the treatment of Flaviridae infections
AU2003248748A1 (en) 2002-06-28 2004-01-19 Idenix (Cayman) Limited 2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
KR20050088079A (en) 2002-11-15 2005-09-01 이데닉스 (케이만) 리미티드 2'-branched nucleosides and flaviviridae mutation
RU2005133093A (en) * 2003-03-28 2006-07-27 Фармассет, Инк. (Us) COMPOUNDS FOR TREATMENT OF FLAVIVIRAL INFECTIONS
CA2520148A1 (en) * 2003-04-01 2004-12-23 Intermune, Inc. Compositions and methods for treating coronavirus infection and sars
CA2521650A1 (en) * 2003-04-17 2004-10-28 Ares Trading S.A. Interferon beta in severe acute respiratory syndrome (sars)
US7429572B2 (en) 2003-05-30 2008-09-30 Pharmasset, Inc. Modified fluorinated nucleoside analogues
CA2527711A1 (en) * 2003-06-09 2004-12-16 Genome Institute Of Singapore Inhibition of sars coronavirus infection with clinically approved antiviral drugs
JP2007501806A (en) * 2003-08-13 2007-02-01 ハワード ジェイ． スミス アンド アソシエイツ ピーティーワイ エルティーディー How to treat a viral infection
AR045870A1 (en) * 2003-10-11 2005-11-16 Vertex Pharma COMBINATION THERAPY FOR HEPATITIS C VIRUS INFECTION
WO2006031725A2 (en) 2004-09-14 2006-03-23 Pharmasset, Inc. Preparation of 2'­fluoro-2'- alkyl- substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives
MY141025A (en) * 2004-10-29 2010-02-25 Vertex Pharma Dose forms
DK1976516T3 (en) * 2006-01-09 2013-07-15 Romark Lab Lc TREATMENT OF VIRAL HEPATITIS
US7964580B2 (en) 2007-03-30 2011-06-21 Pharmasset, Inc. Nucleoside phosphoramidate prodrugs
BRPI0814363A2 (en) 2007-07-25 2015-01-27 Biolex Therapeutics Inc INTERFERON CONTROLLED RELEASE DRUG PRODUCTS AND HCV INFECTION TREATMENT USING THE SAME
TW200946541A (en) 2008-03-27 2009-11-16 Idenix Pharmaceuticals Inc Solid forms of an anti-HIV phosphoindole compound
EP2376088B1 (en) 2008-12-23 2017-02-22 Gilead Pharmasset LLC 6-O-Substituted-2-amino-purine nucleoside phosphoramidates
EA019295B1 (en) 2008-12-23 2014-02-28 Джилид Фармассет, Ллс. Synthesis of purine nucleosides and process for preparing them
US8551973B2 (en) 2008-12-23 2013-10-08 Gilead Pharmasset Llc Nucleoside analogs
JP2012526149A (en) 2009-05-08 2012-10-25 サイクローン・ファーマシューティカルズ・インコーポレイテッド Alpha thymosin peptide as a vaccine enhancer
TWI576352B (en) 2009-05-20 2017-04-01 基利法瑪席特有限責任公司 Nucleoside phosphoramidates
US8618076B2 (en) 2009-05-20 2013-12-31 Gilead Pharmasset Llc Nucleoside phosphoramidates
JP2013527145A (en) 2010-03-31 2013-06-27 ギリード・ファーマセット・エルエルシー Stereoselective synthesis of phosphorus-containing activators
WO2012045704A1 (en) * 2010-10-05 2012-04-12 Novartis Ag New treatments of hepatitis c virus infection
AR084044A1 (en) 2010-11-30 2013-04-17 Pharmasset Inc 2’-ESPIRO-NUCLEOSID COMPOUNDS
JP6253991B2 (en) * 2011-03-02 2017-12-27 ジェローム シェンターク， Composition, therapy and diagnostic method for the treatment of hepatic steatosis alone or with hepatitis C virus infection
JP6073897B2 (en) 2011-09-16 2017-02-01 ギリアド ファーマセット エルエルシー Methods for treating HCV
US8889159B2 (en) 2011-11-29 2014-11-18 Gilead Pharmasset Llc Compositions and methods for treating hepatitis C virus
ES2771458T3 (en) 2013-01-31 2020-07-06 Gilead Pharmasset Llc Combination formulation of two antiviral compounds
PL3650014T3 (en) 2013-08-27 2022-01-31 Gilead Pharmasset Llc Combination formulation of two antiviral compounds

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Also Published As

Publication number Publication date
CN1309568A (en) 2001-08-22
EP2305287A1 (en) 2011-04-06
NZ507621A (en) 2002-11-26
BR9910505A (en) 2001-01-02
KR20010043624A (en) 2001-05-25
AU2005220271B9 (en) 2010-12-09
JP5281726B2 (en) 2013-09-04
DE69901321D1 (en) 2002-05-29
SK288038B6 (en) 2013-01-02
CA2331823A1 (en) 1999-11-25
EP1213029A1 (en) 2002-06-12
DK0956861T3 (en) 2002-07-01
HUP0103423A2 (en) 2002-01-28
MY129244A (en) 2007-03-30
IL207259A0 (en) 2010-12-30
WO1999059621A1 (en) 1999-11-25
AU2005220271B8 (en) 2010-11-18
EP0956861A1 (en) 1999-11-17
PT956861E (en) 2002-08-30
NO20005755L (en) 2001-01-12
AU3860099A (en) 1999-12-06
AU2005220271A1 (en) 2005-11-03
AR019551A1 (en) 2002-02-27
SK17102000A3 (en) 2001-05-10
KR100694345B1 (en) 2007-03-12
CN1230198C (en) 2005-12-07
HUP0103423A3 (en) 2003-11-28
HK1021131A1 (en) 2000-06-02
IL207259A (en) 2016-08-31
AU766597B2 (en) 2003-10-16
AU2005220271B2 (en) 2005-11-03
TWI277424B (en) 2007-04-01
HU230432B1 (en) 2016-06-28
CZ20004177A3 (en) 2001-04-11
NO330715B1 (en) 2011-06-20
IL139220A0 (en) 2001-11-25
NO20005755D0 (en) 2000-11-14
ES2172288T3 (en) 2002-09-16
JP2011173898A (en) 2011-09-08
JP2002515453A (en) 2002-05-28
IL139220A (en) 2013-02-28
CZ300540B6 (en) 2009-06-10
EP0956861B1 (en) 2002-04-24
DE69901321T2 (en) 2002-12-12

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