ATE20349T1 - HETEROCYCLIC SUBSTITUTED NITRILES, THEIR PRODUCTION AND USE AS PHARMACEUTICALS. - Google Patents
HETEROCYCLIC SUBSTITUTED NITRILES, THEIR PRODUCTION AND USE AS PHARMACEUTICALS.Info
- Publication number
- ATE20349T1 ATE20349T1 AT83111277T AT83111277T ATE20349T1 AT E20349 T1 ATE20349 T1 AT E20349T1 AT 83111277 T AT83111277 T AT 83111277T AT 83111277 T AT83111277 T AT 83111277T AT E20349 T1 ATE20349 T1 AT E20349T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceuticals
- production
- heterocyclic substituted
- substituted nitriles
- nitriles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Abstract
Heterocyclically substituted nitriles of the formula I <IMAGE> I where X is SO2, CO, S, SO or CH2, A is an alkylene or alkenylene radical of not more than 6 carbon atoms, B is -CH=CH- or S, and R1 and R2 are each hydrogen, halogen, C1-C3-alkyl, C1-C3-alkoxy, nitro or trifluoromethyl, and their preparation and use. The novel substances are useful for treating disorders.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19823242477 DE3242477A1 (en) | 1982-11-18 | 1982-11-18 | HETEROCYCLICALLY SUBSTITUTED NITRILES, THEIR PRODUCTION AND USE AS MEDICINAL PRODUCTS |
EP83111277A EP0110219B1 (en) | 1982-11-18 | 1983-11-11 | Heterocyclic substituted nitriles, their production and their use as medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE20349T1 true ATE20349T1 (en) | 1986-06-15 |
Family
ID=6178324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT83111277T ATE20349T1 (en) | 1982-11-18 | 1983-11-11 | HETEROCYCLIC SUBSTITUTED NITRILES, THEIR PRODUCTION AND USE AS PHARMACEUTICALS. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4563474A (en) |
EP (1) | EP0110219B1 (en) |
JP (1) | JPS59108765A (en) |
AT (1) | ATE20349T1 (en) |
CA (1) | CA1207326A (en) |
DE (2) | DE3242477A1 (en) |
DK (1) | DK527183A (en) |
HU (1) | HU189775B (en) |
ZA (1) | ZA838571B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI862513A (en) * | 1985-07-04 | 1987-01-05 | Chemie Linz Ag | NYA TIENO-1,2-THIAZOLDERIVAT, FOERFARANDE FOER DERAS FRAMSTAELLNING OCH DESSA INNEHAOLLANDE PHARMACEUTICAL PREPARAT. |
EP0323869A1 (en) * | 1988-01-06 | 1989-07-12 | Shell Internationale Researchmaatschappij B.V. | Saccharin derivatives |
US5728845A (en) * | 1995-08-29 | 1998-03-17 | Celgene Corporation | Immunotherapeutic nitriles |
RU2445104C2 (en) * | 2009-05-13 | 2012-03-20 | Владимир Владимирович Романов | Method and homeopathic agent for treating hypothermia and convulsions in poultry |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA454944A (en) * | 1949-03-08 | H. Fletcher John | Process for preparing imides | |
US2492554A (en) * | 1946-07-25 | 1949-12-27 | Nopco Chem Co | Process for preparing beta-phthalimido propane derivatives |
FR957381A (en) * | 1946-12-17 | 1950-02-18 | ||
US2992223A (en) * | 1957-12-24 | 1961-07-11 | American Cyanamid Co | Nu beta-cyanovinyl succinimide |
DE1135461B (en) * | 1959-05-08 | 1962-08-30 | Knoll Ag | Process for the production of basic substituted phthalimidines |
US3980634A (en) * | 1973-07-02 | 1976-09-14 | Eastman Kodak Company | Phthalimidyl-azo aniline type compounds and polyester fibers dyed therewith |
DD123741A5 (en) * | 1975-03-06 | 1977-01-12 | ||
US4115398A (en) * | 1977-01-05 | 1978-09-19 | Kowa Company Ltd. | Isoindoline derivatives and the acid addition salts thereof and process for the preparation of same |
EP0031088A1 (en) * | 1979-12-19 | 1981-07-01 | Hoechst Aktiengesellschaft | Benzene-sulfonyl ureas, processes for their preparation, pharmaceutical compositions based on these compounds and their use |
FR2492376A1 (en) * | 1980-10-17 | 1982-04-23 | Cird | POLYMETHYLENE-4,5-ISOTHIAZOLIN-4-ONES-3, PROCESS FOR THEIR PREPARATION AND THEIR USE AS BACTERICIDES AND FUNGICIDES |
-
1982
- 1982-11-18 DE DE19823242477 patent/DE3242477A1/en not_active Withdrawn
-
1983
- 1983-11-11 AT AT83111277T patent/ATE20349T1/en not_active IP Right Cessation
- 1983-11-11 EP EP83111277A patent/EP0110219B1/en not_active Expired
- 1983-11-11 DE DE8383111277T patent/DE3364093D1/en not_active Expired
- 1983-11-15 CA CA000441170A patent/CA1207326A/en not_active Expired
- 1983-11-16 US US06/552,443 patent/US4563474A/en not_active Expired - Lifetime
- 1983-11-17 DK DK527183A patent/DK527183A/en not_active Application Discontinuation
- 1983-11-17 JP JP58215143A patent/JPS59108765A/en active Pending
- 1983-11-17 ZA ZA838571A patent/ZA838571B/en unknown
- 1983-11-17 HU HU833966A patent/HU189775B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE3364093D1 (en) | 1986-07-17 |
CA1207326A (en) | 1986-07-08 |
ZA838571B (en) | 1984-07-25 |
JPS59108765A (en) | 1984-06-23 |
HU189775B (en) | 1986-07-28 |
DK527183D0 (en) | 1983-11-17 |
DE3242477A1 (en) | 1984-05-24 |
EP0110219B1 (en) | 1986-06-11 |
EP0110219A1 (en) | 1984-06-13 |
US4563474A (en) | 1986-01-07 |
DK527183A (en) | 1984-05-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
REN | Ceased due to non-payment of the annual fee |