ATE196472T1 - Antibiotische cephalosporine einen substituierten benzyloxyimino-radikal in position 7 tragend - Google Patents
Antibiotische cephalosporine einen substituierten benzyloxyimino-radikal in position 7 tragendInfo
- Publication number
- ATE196472T1 ATE196472T1 AT92403361T AT92403361T ATE196472T1 AT E196472 T1 ATE196472 T1 AT E196472T1 AT 92403361 T AT92403361 T AT 92403361T AT 92403361 T AT92403361 T AT 92403361T AT E196472 T1 ATE196472 T1 AT E196472T1
- Authority
- AT
- Austria
- Prior art keywords
- cephalosporins
- substituted
- carrying
- new
- alkyl
- Prior art date
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 3
- 229940124587 cephalosporin Drugs 0.000 title abstract 3
- 230000003115 biocidal effect Effects 0.000 title 1
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- -1 benzyloxyimino group Chemical group 0.000 abstract 3
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 150000001780 cephalosporins Chemical class 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004457 alkyl amino carbonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000004473 dialkylaminocarbonyl group Chemical group 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 125000003396 thiol group Chemical class [H]S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/44—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
- C07C239/08—Hydroxylamino compounds or their ethers or esters
- C07C239/20—Hydroxylamino compounds or their ethers or esters having oxygen atoms of hydroxylamino groups etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/57—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and carboxyl groups, other than cyano groups, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/56—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
- C07C47/565—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups all hydroxy groups bound to the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9115416A FR2684994B1 (fr) | 1991-12-12 | 1991-12-12 | Nouvelles cephalosporines comportant en position 7, un radical benzyloxyimino substitue, leur procede de preparation et leur application comme medicaments. |
| FR9211520A FR2696180B1 (fr) | 1992-09-28 | 1992-09-28 | Nouvelles céphalosporines comportant en position 7, un radical benzyloxyimino substitué, leur procédé de préparation et leur application comme médicaments. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE196472T1 true ATE196472T1 (de) | 2000-10-15 |
Family
ID=26229111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92403361T ATE196472T1 (de) | 1991-12-12 | 1992-12-11 | Antibiotische cephalosporine einen substituierten benzyloxyimino-radikal in position 7 tragend |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5455238A (de) |
| EP (2) | EP1016646A1 (de) |
| JP (2) | JP2670954B2 (de) |
| KR (1) | KR0143092B1 (de) |
| CN (1) | CN1061045C (de) |
| AT (1) | ATE196472T1 (de) |
| AU (1) | AU693932B2 (de) |
| CA (1) | CA2085137A1 (de) |
| DE (1) | DE69231464T2 (de) |
| DK (1) | DK0551034T3 (de) |
| ES (1) | ES2149770T3 (de) |
| GR (1) | GR3034937T3 (de) |
| HU (2) | HU0104737D0 (de) |
| MX (1) | MX9207198A (de) |
| PT (1) | PT551034E (de) |
| RU (1) | RU2114852C1 (de) |
| SG (1) | SG45426A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5587372A (en) * | 1991-12-12 | 1996-12-24 | Roussel Uclaf | Cephalosporins |
| JPH07173168A (ja) * | 1993-07-14 | 1995-07-11 | Sumitomo Chem Co Ltd | セフェム系化合物、その製法、およびそれのセフェム系抗生物質製造への利用 |
| FR2722790B1 (fr) | 1994-07-19 | 1996-10-04 | Roussel Uclaf | Nouvelles cephalosporines comportant en position 7 un radical benzyloxymino subtitue, leur procede de preparation leur application comme medicaments |
| KR100248851B1 (ko) * | 1994-08-16 | 2000-04-01 | 이치로 키타사토 | 신규 세펨 유도체 |
| GB9419274D0 (en) * | 1994-09-23 | 1994-11-09 | Orion Yhtymae Oy | New method for the preparation of 3,4-dihydroxy-5-nitrobenzaldehyde |
| JPH08319291A (ja) * | 1995-05-25 | 1996-12-03 | Meiji Seika Kaisha Ltd | 新規セフェム誘導体 |
| FR2737893B1 (fr) * | 1995-08-16 | 1997-09-12 | Roussel Uclaf | Nouvelles cephalosporines comportant en position 7, un radical benzyloxyimino substitue, leur procede et intermediaires de preparation, leur application comme medicaments |
| US6362009B1 (en) | 1997-11-21 | 2002-03-26 | Merck & Co., Inc. | Solid phase synthesis of heterocycles |
| WO2009073620A2 (en) | 2007-11-30 | 2009-06-11 | Newlink Genetics | Ido inhibitors |
| FR2948660B1 (fr) | 2009-07-30 | 2011-08-19 | Oroxcell | Derives de 2-amino-2-phenyl-alkanol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| CN105037165B (zh) * | 2015-07-02 | 2017-03-29 | 江苏新淮河医药科技有限公司 | 1，3‑二（2‑溴‑5‑甲氧基苯乙烯基）‑2，4，6‑三硝基苯化合物及其制备方法 |
| JP2024068297A (ja) * | 2022-11-08 | 2024-05-20 | 信越化学工業株式会社 | アミン化合物、化学増幅レジスト組成物及びパターン形成方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3619187A (en) | 1968-02-12 | 1971-11-09 | Gaf Corp | Process for preparing colored photoresists |
| US4486586A (en) * | 1983-02-10 | 1984-12-04 | Bristol-Myers Company | Cephalosporin derivatives |
| DE3479731D1 (en) * | 1983-07-07 | 1989-10-19 | Beecham Group Plc | Substituted phenylglycine derivatives of beta-lactam antibiotics |
| US5373000A (en) * | 1985-12-26 | 1994-12-13 | Eisai Co., Ltd. | 7Beta-(thiadiazolyl)-2-iminoacetamido-3cephem compounds |
| GB8623211D0 (en) * | 1986-09-26 | 1986-10-29 | Glaxo Group Ltd | Chemical compounds |
| JPS63132893A (ja) * | 1986-11-25 | 1988-06-04 | Mochida Pharmaceut Co Ltd | 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤 |
| FR2622585B1 (fr) * | 1987-11-03 | 1991-04-19 | Roussel Uclaf | Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus |
| JPH0334986A (ja) * | 1989-06-29 | 1991-02-14 | Hisayasu Ishimaru | セファロスポリン系化合物 |
| FR2663332B1 (fr) | 1990-06-15 | 1997-11-07 | Roussel Uclaf | Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus. |
| US5373001A (en) * | 1990-06-15 | 1994-12-13 | Roussel Uclaf | Cephalosporins |
| US5397779A (en) * | 1990-06-15 | 1995-03-14 | Roussel-Uclaf | Cephalosporins |
| US5234920A (en) * | 1990-08-23 | 1993-08-10 | Bristol-Myers Squibb Company | Antibiotic C-7 catechol-substituted cephalosporin compounds, compositions, and method of use thereof |
| US5095012A (en) * | 1990-08-23 | 1992-03-10 | Bristol-Myers Squibb Company | Antibiotic c-7 catechol-substituted cephalosporin compounds, compositions, and method of use thereof |
-
1992
- 1992-12-11 AT AT92403361T patent/ATE196472T1/de not_active IP Right Cessation
- 1992-12-11 ES ES92403361T patent/ES2149770T3/es not_active Expired - Lifetime
- 1992-12-11 DK DK92403361T patent/DK0551034T3/da active
- 1992-12-11 SG SG1996007288A patent/SG45426A1/en unknown
- 1992-12-11 CA CA002085137A patent/CA2085137A1/fr not_active Abandoned
- 1992-12-11 KR KR1019920023908A patent/KR0143092B1/ko not_active Expired - Fee Related
- 1992-12-11 DE DE69231464T patent/DE69231464T2/de not_active Expired - Fee Related
- 1992-12-11 HU HU0104737A patent/HU0104737D0/hu unknown
- 1992-12-11 EP EP00200918A patent/EP1016646A1/de not_active Withdrawn
- 1992-12-11 RU RU92004562A patent/RU2114852C1/ru active
- 1992-12-11 EP EP92403361A patent/EP0551034B1/de not_active Expired - Lifetime
- 1992-12-11 US US07/989,235 patent/US5455238A/en not_active Expired - Fee Related
- 1992-12-11 MX MX9207198A patent/MX9207198A/es not_active IP Right Cessation
- 1992-12-11 PT PT92403361T patent/PT551034E/pt unknown
- 1992-12-11 HU HU9203929A patent/HU221478B/hu not_active IP Right Cessation
- 1992-12-12 CN CN92114376A patent/CN1061045C/zh not_active Expired - Fee Related
- 1992-12-14 JP JP4352801A patent/JP2670954B2/ja not_active Expired - Fee Related
-
1995
- 1995-10-26 AU AU34475/95A patent/AU693932B2/en not_active Ceased
-
1997
- 1997-03-17 JP JP08241497A patent/JP3288951B2/ja not_active Expired - Fee Related
-
2000
- 2000-11-29 GR GR20000402644T patent/GR3034937T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0551034A3 (en) | 1993-08-25 |
| GR3034937T3 (en) | 2001-02-28 |
| MX9207198A (es) | 1993-07-01 |
| AU664058B2 (en) | 1995-11-02 |
| AU3447595A (en) | 1996-02-08 |
| JP2670954B2 (ja) | 1997-10-29 |
| CN1073177A (zh) | 1993-06-16 |
| JP3288951B2 (ja) | 2002-06-04 |
| HU221478B (en) | 2002-10-28 |
| RU2114852C1 (ru) | 1998-07-10 |
| HUT78024A (hu) | 1999-05-28 |
| AU3011392A (en) | 1993-06-17 |
| AU693932B2 (en) | 1998-07-09 |
| EP0551034B1 (de) | 2000-09-20 |
| JPH0641148A (ja) | 1994-02-15 |
| DK0551034T3 (da) | 2001-01-29 |
| JPH1029995A (ja) | 1998-02-03 |
| US5455238A (en) | 1995-10-03 |
| EP1016646A1 (de) | 2000-07-05 |
| DE69231464D1 (de) | 2000-10-26 |
| CN1061045C (zh) | 2001-01-24 |
| EP0551034A2 (de) | 1993-07-14 |
| HU0104737D0 (en) | 2001-12-28 |
| HU9203929D0 (en) | 1993-04-28 |
| ES2149770T3 (es) | 2000-11-16 |
| PT551034E (pt) | 2001-01-31 |
| CA2085137A1 (fr) | 1993-06-13 |
| SG45426A1 (en) | 1998-01-16 |
| DE69231464T2 (de) | 2001-04-19 |
| KR0143092B1 (ko) | 1998-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |