ATE19243T1 - Saure salze von 2-piperazinopyrimidin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. - Google Patents

Saure salze von 2-piperazinopyrimidin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
ATE19243T1
ATE19243T1 AT83402168T AT83402168T ATE19243T1 AT E19243 T1 ATE19243 T1 AT E19243T1 AT 83402168 T AT83402168 T AT 83402168T AT 83402168 T AT83402168 T AT 83402168T AT E19243 T1 ATE19243 T1 AT E19243T1
Authority
AT
Austria
Prior art keywords
acid salts
piperazinopyrimidine
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
AT83402168T
Other languages
English (en)
Inventor
Emilio Crisafulli
Marco Frigerio
Jean-Pierre Chambon
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of ATE19243T1 publication Critical patent/ATE19243T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/10—Succinic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/145—Maleic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/15—Fumaric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/255—Tartaric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT83402168T 1982-11-12 1983-11-09 Saure salze von 2-piperazinopyrimidin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. ATE19243T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8218975A FR2536071B1 (fr) 1982-11-12 1982-11-12 Sels acides de 2-piperazinopyrimidine, procede pour leur preparation et compositions pharmaceutiques en contenant
EP83402168A EP0109340B1 (de) 1982-11-12 1983-11-09 Saure Salze von 2-Piperazinopyrimidin, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE19243T1 true ATE19243T1 (de) 1986-05-15

Family

ID=9279123

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83402168T ATE19243T1 (de) 1982-11-12 1983-11-09 Saure salze von 2-piperazinopyrimidin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Country Status (10)

Country Link
EP (1) EP0109340B1 (de)
JP (1) JPS59144766A (de)
AT (1) ATE19243T1 (de)
AU (1) AU567311B2 (de)
CA (1) CA1249275A (de)
DE (1) DE3363093D1 (de)
FR (1) FR2536071B1 (de)
IE (1) IE56184B1 (de)
NZ (1) NZ206222A (de)
ZA (1) ZA838423B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2561689B2 (ja) * 1986-02-24 1996-12-11 三井石油化学工業株式会社 神経疾患用治療薬
DE3752141T2 (de) * 1986-02-24 1998-03-26 Mitsui Petrochemical Ind Mittel zur behandlung von neuropathie
YU39503A (sh) * 2000-11-22 2006-05-25 F. Hoffmann-La Roche Ag. Derivati pirimidina
AR038368A1 (es) 2002-02-01 2005-01-12 Novartis Ag Compuestos n-pirimidin-2-il-aminas sustituidas como inhibidores de ige, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de un medicamento
JP4726622B2 (ja) * 2005-12-14 2011-07-20 三洋電機株式会社 リード付電池

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US985657A (en) * 1910-12-10 1911-02-28 Baldwin Locomotive Works Car-truck.
US2985657A (en) * 1959-10-12 1961-05-23 Paul A J Janssen 1-(aroylalkyl)-4-heterocyclylpiperazines
US4547505A (en) * 1983-03-25 1985-10-15 Degussa Aktiengesellschaft N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
DE3321969A1 (de) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
DE3363093D1 (en) 1986-05-22
FR2536071B1 (fr) 1986-07-11
ZA838423B (en) 1984-06-27
NZ206222A (en) 1985-09-13
EP0109340A2 (de) 1984-05-23
EP0109340B1 (de) 1986-04-16
IE832631L (en) 1984-05-12
JPS59144766A (ja) 1984-08-18
IE56184B1 (en) 1991-05-08
EP0109340A3 (en) 1984-06-27
AU2116483A (en) 1984-05-17
CA1249275A (en) 1989-01-24
AU567311B2 (en) 1987-11-19
FR2536071A1 (fr) 1984-05-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee