ATE178071T1 - Endothelin-antagonisierendes peptid - Google Patents
Endothelin-antagonisierendes peptidInfo
- Publication number
- ATE178071T1 ATE178071T1 AT95111532T AT95111532T ATE178071T1 AT E178071 T1 ATE178071 T1 AT E178071T1 AT 95111532 T AT95111532 T AT 95111532T AT 95111532 T AT95111532 T AT 95111532T AT E178071 T1 ATE178071 T1 AT E178071T1
- Authority
- AT
- Austria
- Prior art keywords
- endothelin
- antagonizing peptide
- peptide
- endothelin antagonizing
- benzhydryloxy
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 108050009340 Endothelin Proteins 0.000 title 1
- 102000002045 Endothelin Human genes 0.000 title 1
- 230000003042 antagnostic effect Effects 0.000 title 1
- ZUBDGKVDJUIMQQ-UBFCDGJISA-N endothelin-1 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(O)=O)NC(=O)[C@H]1NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](C(C)C)NC(=O)[C@H]2CSSC[C@@H](C(N[C@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)CSSC1)C1=CNC=N1 ZUBDGKVDJUIMQQ-UBFCDGJISA-N 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- -1 benzyloxy, benzhydryloxy Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17268994 | 1994-07-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE178071T1 true ATE178071T1 (de) | 1999-04-15 |
Family
ID=15946539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95111532T ATE178071T1 (de) | 1994-07-25 | 1995-07-21 | Endothelin-antagonisierendes peptid |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0698613B1 (de) |
| AT (1) | ATE178071T1 (de) |
| DE (1) | DE69508496T2 (de) |
| ES (1) | ES2130477T3 (de) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2669339B1 (fr) * | 1990-11-21 | 1995-03-03 | Roussel Uclaf | Nouveaux derives peptidiques, procede de preparation et application a titre de medicaments de ces nouveaux derives. |
| EP0603399B1 (de) | 1991-12-27 | 2002-09-11 | Kyowa Hakko Kogyo Kabushiki Kaisha | Peptide als antagonisten von endothelin |
-
1995
- 1995-07-21 EP EP95111532A patent/EP0698613B1/de not_active Expired - Lifetime
- 1995-07-21 DE DE69508496T patent/DE69508496T2/de not_active Expired - Fee Related
- 1995-07-21 AT AT95111532T patent/ATE178071T1/de not_active IP Right Cessation
- 1995-07-21 ES ES95111532T patent/ES2130477T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69508496T2 (de) | 1999-08-12 |
| EP0698613A1 (de) | 1996-02-28 |
| ES2130477T3 (es) | 1999-07-01 |
| DE69508496D1 (de) | 1999-04-29 |
| EP0698613B1 (de) | 1999-03-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |