ATE160349T1 - ANTIHYPERTENSIVE BENZOPYRAN DERIVATIVES - Google Patents
ANTIHYPERTENSIVE BENZOPYRAN DERIVATIVESInfo
- Publication number
- ATE160349T1 ATE160349T1 AT91903477T AT91903477T ATE160349T1 AT E160349 T1 ATE160349 T1 AT E160349T1 AT 91903477 T AT91903477 T AT 91903477T AT 91903477 T AT91903477 T AT 91903477T AT E160349 T1 ATE160349 T1 AT E160349T1
- Authority
- AT
- Austria
- Prior art keywords
- antihypertensive
- benzopyran derivatives
- benzopyran
- derivatives
- hypertension
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Disclosed herein are novel benzopyrans having pharmacological activity, to a process for preparing them, to pharmaceutical compositions containing them, and to their use in the treatment of hypertension.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/417,350 US4983612A (en) | 1989-10-05 | 1989-10-05 | Antihypertensive benzopyran derivatives |
PCT/US1991/000124 WO1992012153A1 (en) | 1989-10-05 | 1991-01-07 | Novel antihypertensive benzopyran derivatives |
CA002100273A CA2100273A1 (en) | 1989-10-05 | 1991-01-07 | Antihypertensive benzopyran derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE160349T1 true ATE160349T1 (en) | 1997-12-15 |
Family
ID=25676366
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT91903477T ATE160349T1 (en) | 1989-10-05 | 1991-01-07 | ANTIHYPERTENSIVE BENZOPYRAN DERIVATIVES |
Country Status (10)
Country | Link |
---|---|
US (2) | US4983612A (en) |
EP (1) | EP0566567B1 (en) |
JP (1) | JPH06502841A (en) |
AT (1) | ATE160349T1 (en) |
CA (1) | CA2100273A1 (en) |
DE (1) | DE69128254T2 (en) |
DK (1) | DK0566567T3 (en) |
ES (1) | ES2111561T3 (en) |
GR (1) | GR3025530T3 (en) |
WO (1) | WO1992012153A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4983612A (en) * | 1989-10-05 | 1991-01-08 | American Home Products Corporation | Antihypertensive benzopyran derivatives |
US5179118A (en) * | 1992-05-08 | 1993-01-12 | American Home Products Corporation | Indazolanonyl derivatives of benzopyrans |
US5500442A (en) * | 1994-06-10 | 1996-03-19 | American Home Products Corporation | Cyclobut-3-ene-1,2-dione derivatives as smooth muscle relaxants |
US5869478A (en) * | 1995-06-07 | 1999-02-09 | Bristol-Myers Squibb Company | Sulfonamido substituted benzopyran derivatives |
DE10042093A1 (en) * | 2000-08-26 | 2002-03-07 | Dresden Arzneimittel | Anticonvulsant 6,7-dihydro-pyrrolo [3,4-d] pyridin-5-ones and process for their preparation |
AU2006284860A1 (en) * | 2005-09-01 | 2007-03-08 | Janssen Pharmaceutica N.V. | Benzopyran and pyranopyridine derivatives as potassium channel openers |
EP1937669B9 (en) * | 2005-09-01 | 2012-07-18 | Janssen Pharmaceutica NV | Novel benzopyran derivatives as potassium channel openers |
US8839547B2 (en) * | 2006-02-24 | 2014-09-23 | David Pekin | Reel system with line tension measurement capability |
US9050302B2 (en) | 2013-03-01 | 2015-06-09 | Jazz Pharmaceuticals Ireland Limited | Method of administration of gamma hydroxybutyrate with monocarboxylate transporters |
TWI783978B (en) * | 2017-03-08 | 2022-11-21 | 美商林伯士拉克許米公司 | Tyk2 inhibitors, uses, and methods for production thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8409745D0 (en) * | 1984-04-14 | 1984-05-23 | Beecham Group Plc | Active compounds |
US4889852A (en) * | 1987-09-11 | 1989-12-26 | Duphar International Research B.V. | Anxiolytically active piperazine derivatives |
IL88035A0 (en) * | 1987-10-27 | 1989-06-30 | American Home Prod | Benzopyran derivatives,their preparation and pharmaceutical compositions containing them |
WO1990012011A1 (en) * | 1989-04-12 | 1990-10-18 | American Home Products Corporation | Novel antihypertensive benzopyran derivatives |
US4983612A (en) * | 1989-10-05 | 1991-01-08 | American Home Products Corporation | Antihypertensive benzopyran derivatives |
-
1989
- 1989-10-05 US US07/417,350 patent/US4983612A/en not_active Expired - Lifetime
-
1990
- 1990-09-11 US US07/580,902 patent/US5021418A/en not_active Expired - Lifetime
-
1991
- 1991-01-07 DE DE69128254T patent/DE69128254T2/en not_active Expired - Fee Related
- 1991-01-07 AT AT91903477T patent/ATE160349T1/en not_active IP Right Cessation
- 1991-01-07 CA CA002100273A patent/CA2100273A1/en not_active Abandoned
- 1991-01-07 ES ES91903477T patent/ES2111561T3/en not_active Expired - Lifetime
- 1991-01-07 DK DK91903477.7T patent/DK0566567T3/en active
- 1991-01-07 WO PCT/US1991/000124 patent/WO1992012153A1/en active IP Right Grant
- 1991-01-07 EP EP91903477A patent/EP0566567B1/en not_active Expired - Lifetime
- 1991-01-07 JP JP3503552A patent/JPH06502841A/en active Pending
-
1997
- 1997-11-27 GR GR970403178T patent/GR3025530T3/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2100273A1 (en) | 1992-07-08 |
DK0566567T3 (en) | 1998-02-23 |
ES2111561T3 (en) | 1998-03-16 |
GR3025530T3 (en) | 1998-02-27 |
EP0566567A1 (en) | 1993-10-27 |
US5021418A (en) | 1991-06-04 |
EP0566567B1 (en) | 1997-11-19 |
DE69128254T2 (en) | 1998-04-09 |
JPH06502841A (en) | 1994-03-31 |
WO1992012153A1 (en) | 1992-07-23 |
DE69128254D1 (en) | 1998-01-02 |
US4983612A (en) | 1991-01-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUT49592A (en) | Process for producing bis/hydroxymethyl/-cyclobutyl-purines and pyrimidines, as well as pharmaceutical compositions comprising same | |
IT8747630A0 (en) | DICHLOROANILINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND PROCEDURE FOR PRODUCING THEM | |
NO892218L (en) | PROCEDURE FOR THE PREPARATION OF BENZOPYRAN DERIVATIVES. | |
NO174467C (en) | Analogous process for the preparation of therapeutically active chromane derivatives | |
DE3877406D1 (en) | BENZOTHIAZOLINONE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION. | |
SE8904361D0 (en) | NEW CHROMAN AND THIOCHROMAN DERIVATIVES | |
HUT58066A (en) | Process for producing benzopyran derivatives and their heterocyclic analogs, as well as antiischaemic pharmaceutical compositions | |
DK314487A (en) | benzoxepin | |
ATE160349T1 (en) | ANTIHYPERTENSIVE BENZOPYRAN DERIVATIVES | |
IL80201A0 (en) | Labdane derivatives,processes for their preparation and pharmaceutical compositions containing them | |
FI93106C (en) | Process for the preparation of 2-iminobenzothiazoline derivatives useful as medicaments | |
NZ233912A (en) | Pyridazinyl-3-oxy substituted chroman derivatives, pharmaceutical compositions, methods of treatment and preparation | |
NO176477C (en) | Analogous Process for Preparing Therapeutically Active 2-Alkoxymethyl Substituted Chromane Derivatives | |
NO174391C (en) | Analogous process for the preparation of therapeutically active chromane derivatives | |
HUT49598A (en) | Process for producing chromone derivatives and pharmaceutical compositions comprising same as active ingredient | |
IL89968A (en) | 4-oxo quinazoline derivatives, processes for their preparation and pharmaceutical compositions comprising them | |
NO174422C (en) | Analogous process for the preparation of therapeutically active chromane derivatives | |
ATE149507T1 (en) | SOLUBLE, NON-TOXIC DERIVATIVES OF BASIC POLYEN MACROLIDS, THEIR PREPARATION AND USE | |
HUT63151A (en) | Process for producing new benzimidazole-2-sulfonamide and imidazopyuridine-2-sylfonamide derivatives, as well as pharmaceutical compositions comprising same as active ingredient | |
IT1227362B (en) | INDOLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTI-THROMBOTIC DRUGS | |
KR900007816A (en) | Cyclopropyl-substituted azolylmethylcarbinol, its preparation method and its use as a medicament | |
DK395788A (en) | SOLUBLE SILYBIN DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE RELATIONSHIPS | |
IT8819958A0 (en) | PHARMACOLOGICALLY ACTIVE ALKYLTIOBENZIMIDAZOLE DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION. | |
EP0420266A3 (en) | Chromene or thiochromene derivatives, process for preparing the same, intermediate therefor, pharmaceutical compositions containing said derivatives and the use of said derivatives | |
DK478485D0 (en) | 4-OXO-PYRIDO (2,3-D) PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND USE |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |