ATE136553T1 - METHYLPYRROLIDONE CHITOSAN, METHOD FOR THE PRODUCTION THEREOF AND ITS USES - Google Patents

METHYLPYRROLIDONE CHITOSAN, METHOD FOR THE PRODUCTION THEREOF AND ITS USES

Info

Publication number
ATE136553T1
ATE136553T1 AT91920494T AT91920494T ATE136553T1 AT E136553 T1 ATE136553 T1 AT E136553T1 AT 91920494 T AT91920494 T AT 91920494T AT 91920494 T AT91920494 T AT 91920494T AT E136553 T1 ATE136553 T1 AT E136553T1
Authority
AT
Austria
Prior art keywords
pct
production
sec
formula
recurring units
Prior art date
Application number
AT91920494T
Other languages
German (de)
Inventor
Ricardo Muzzarelli
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of ATE136553T1 publication Critical patent/ATE136553T1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/00272-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof

Abstract

PCT No. PCT/EP91/02168 Sec. 371 Date Jul. 27, 1992 Sec. 102(e) Date Jul. 27, 1992 PCT Filed Nov. 18, 1991 PCT Pub. No. WO92/09635 PCT Pub. Date Jun. 11, 1992.Modified chitins and chitosans with recurring units of the formula <IMAGE> wherein R denotes -NH2, -NHCOCH3 and R', with R' being present in at least 30% of the recurring units, characterized in that R' represents a group of the formula their favourable biological properties, these materials are advantageously useful in medical and cosmetical applications.
AT91920494T 1990-11-26 1991-11-18 METHYLPYRROLIDONE CHITOSAN, METHOD FOR THE PRODUCTION THEREOF AND ITS USES ATE136553T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT00064290A IT1243260B (en) 1990-11-26 1990-11-26 METHYL PYROLIDON CHITOSAN, PRODUCTION PROCESS AND ITS USE.

Publications (1)

Publication Number Publication Date
ATE136553T1 true ATE136553T1 (en) 1996-04-15

Family

ID=11099998

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91920494T ATE136553T1 (en) 1990-11-26 1991-11-18 METHYLPYRROLIDONE CHITOSAN, METHOD FOR THE PRODUCTION THEREOF AND ITS USES

Country Status (13)

Country Link
US (1) US5378472A (en)
EP (1) EP0512095B1 (en)
JP (1) JPH05503733A (en)
KR (1) KR927003132A (en)
AT (1) ATE136553T1 (en)
AU (1) AU639163B2 (en)
CA (1) CA2074517A1 (en)
CZ (1) CZ281052B6 (en)
DE (1) DE69118683T2 (en)
ES (1) ES2084838T3 (en)
HU (1) HUT62017A (en)
IT (1) IT1243260B (en)
WO (1) WO1992009635A1 (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4320871C2 (en) * 1993-06-24 1995-05-04 Beiersdorf Ag Cosmetic and dermatological preparations containing delta-aminolevulinic acid
DE4446380A1 (en) * 1994-07-05 1996-01-11 Lohmann Therapie Syst Lts Hydrogel for the application of therapeutic and / or cosmetic agents to the skin
US6486140B2 (en) 1994-07-19 2002-11-26 Medicarb Ab Agents, and methods employing them, for the prevention or reduction of tissue adhesion at a wound site
US5597811A (en) * 1995-04-10 1997-01-28 Amerchol Corporation Oxirane carboxylic acid derivatives of polyglucosamines
WO1996041818A1 (en) * 1995-06-09 1996-12-27 Drohan William N Chitin hydrogels, methods of their production and use
DE19643066C2 (en) * 1996-10-18 1999-07-01 Henkel Kgaa Collagen-free cosmetic preparations and processes for their production
US5770712A (en) * 1997-03-14 1998-06-23 Virginia Tech Intellectual Properties, Inc. Crosslinked hydrogel beads from chitosan
KR19990000270A (en) 1997-06-04 1999-01-15 박원훈 Leukocyte removal filter coated with chitosan
US6197322B1 (en) 1997-12-23 2001-03-06 Kimberly-Clark Worldwide, Inc. Antimicrobial structures
DE19804367C2 (en) * 1998-02-04 2001-11-22 Spiller Biocosmetic Gmbh Dr Cosmetic package removal preparations
IL132212A (en) * 1998-10-23 2003-03-12 Milliken & Co Textile fabric with particle attracting finish
US20030206958A1 (en) * 2000-12-22 2003-11-06 Cattaneo Maurizio V. Chitosan biopolymer for the topical delivery of active agents
US20060004314A1 (en) * 2001-06-14 2006-01-05 Hemcon, Inc. Antimicrobial barriers, systems, and methods formed from hydrophilic polymer structures such as chistosan
US7371403B2 (en) * 2002-06-14 2008-05-13 Providence Health System-Oregon Wound dressing and method for controlling severe, life-threatening bleeding
US8741335B2 (en) 2002-06-14 2014-06-03 Hemcon Medical Technologies, Inc. Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as Chitosan
ATE549996T1 (en) * 2001-06-14 2012-04-15 Gregory Kenton W METHOD FOR PRODUCING CHITOSAN WOUND DRESSINGS
KR20030006788A (en) * 2001-07-16 2003-01-23 이승진 Sustained release polymeric preparation for treatment of periodontal disease
US6926903B2 (en) * 2001-12-04 2005-08-09 Inion Ltd. Resorbable polymer composition, implant and method of making implant
US20050137512A1 (en) * 2003-12-23 2005-06-23 Campbell Todd D. Wound dressing and method for controlling severe, life-threatening bleeding
US8269058B2 (en) * 2002-06-14 2012-09-18 Hemcon Medical Technologies, Inc. Absorbable tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chitosan
EP1402905A1 (en) * 2002-09-24 2004-03-31 The Procter & Gamble Company Liquid absorbent thermoplastic composition comprising superabsorbent material particles of substantially anglelacking shape
EP1402862B1 (en) * 2002-09-24 2007-11-28 The Procter & Gamble Company An absorbent article comprising an absorbent element comprising a liquid absorbent thermoplastic composition
EP1440683A1 (en) * 2003-01-23 2004-07-28 Cognis France S.A. Use of oligoglucosamines in cosmetic or dermatologic compositions
EP1506821B1 (en) * 2003-08-11 2010-11-03 The Procter & Gamble Company Process for improved adhesive application
EP1579831A1 (en) 2004-03-23 2005-09-28 The Procter & Gamble Company An absorbent article comprising edge barriers comprising a liquid absorbent thermoplastic composition
WO2006005211A1 (en) * 2004-07-12 2006-01-19 Gaba International Ag Oral hygiene agents containing a chitosan derivative
US9204957B2 (en) * 2005-03-17 2015-12-08 Hemcon Medical Technologies, Inc. Systems and methods for hemorrhage control and or tissue repair
EP1829561A1 (en) * 2006-03-03 2007-09-05 The Procter and Gamble Company Thermoplastic absorbent materials for proteinaceous or serous bodily fluids
WO2007139845A2 (en) 2006-05-23 2007-12-06 Providence Health System-Oregon D/B/A Providence St. Vincent Medical Center Systems and methods for introducing and applying a bandage structure within a body lumen or hollow body organ
US8932560B2 (en) * 2007-09-04 2015-01-13 University of Maryland, College Parke Advanced functional biocompatible polymeric matrix used as a hemostatic agent and system for damaged tissues and cells
JP5726068B2 (en) * 2008-05-02 2015-05-27 プロビデンス ヘルス システム−オレゴン ディー/ビー/エー プロビデンス セント ビンセント メディカル センター Wound dressing device and method
WO2010042540A1 (en) 2008-10-06 2010-04-15 Providence Health System - Oregon Foam medical devices and methods
AU2010314994B2 (en) 2009-11-09 2016-10-06 Spotlight Technology Partners Llc Fragmented hydrogels
CN102695500A (en) 2009-11-09 2012-09-26 聚光灯技术合伙有限责任公司 Polysaccharide based hydrogels

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61253065A (en) * 1985-05-02 1986-11-10 片倉チツカリン株式会社 Medical composite material of chitosan derivative and collagen and its production
IT1190380B (en) * 1985-06-21 1988-02-16 Consiglio Nazionale Ricerche FUNCTIONALIZED AND CROSSLINED GLUCANS, PREPARATION PROCESS AND INTERMEDIATES, THEIR USES

Also Published As

Publication number Publication date
HUT62017A (en) 1993-03-29
AU8956691A (en) 1992-06-25
DE69118683T2 (en) 1996-08-29
IT1243260B (en) 1994-05-26
JPH05503733A (en) 1993-06-17
HU9202434D0 (en) 1992-10-28
AU639163B2 (en) 1993-07-15
EP0512095A1 (en) 1992-11-11
CZ230592A3 (en) 1993-02-17
ES2084838T3 (en) 1996-05-16
CZ281052B6 (en) 1996-06-12
US5378472A (en) 1995-01-03
KR927003132A (en) 1992-12-17
IT9000642A1 (en) 1992-05-27
EP0512095B1 (en) 1996-04-10
DE69118683D1 (en) 1996-05-15
WO1992009635A1 (en) 1992-06-11
IT9000642A0 (en) 1990-11-26
CA2074517A1 (en) 1992-05-27

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REN Ceased due to non-payment of the annual fee