ATE114156T1 - PRODUCTION OF PROTEINS IN ACTIVE FORM. - Google Patents

PRODUCTION OF PROTEINS IN ACTIVE FORM.

Info

Publication number
ATE114156T1
ATE114156T1 AT88305404T AT88305404T ATE114156T1 AT E114156 T1 ATE114156 T1 AT E114156T1 AT 88305404 T AT88305404 T AT 88305404T AT 88305404 T AT88305404 T AT 88305404T AT E114156 T1 ATE114156 T1 AT E114156T1
Authority
AT
Austria
Prior art keywords
proteins
production
host cells
active form
source
Prior art date
Application number
AT88305404T
Other languages
German (de)
Inventor
Joseph John Patroni
Malcolm Roy Brandon
Original Assignee
Southern Cross Biotech Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Cross Biotech Pty Ltd filed Critical Southern Cross Biotech Pty Ltd
Application granted granted Critical
Publication of ATE114156T1 publication Critical patent/ATE114156T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A method for the recovery of proteins in a solubilized form from host cells including providing a source of host cells incorporating a synthesized or expressed protein; providing a source of at least one cationic surfactant; and treating the host cells with at least one cationic surfactant, in an amount sufficient to effect solubilization of the proteins.
AT88305404T 1987-06-15 1988-06-14 PRODUCTION OF PROTEINS IN ACTIVE FORM. ATE114156T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPI247287 1987-06-15

Publications (1)

Publication Number Publication Date
ATE114156T1 true ATE114156T1 (en) 1994-12-15

Family

ID=3772234

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88305404T ATE114156T1 (en) 1987-06-15 1988-06-14 PRODUCTION OF PROTEINS IN ACTIVE FORM.

Country Status (14)

Country Link
US (1) US4992531A (en)
JP (1) JPS6447389A (en)
KR (1) KR0126767B1 (en)
CN (1) CN1032425C (en)
AT (1) ATE114156T1 (en)
AU (1) AU609824B2 (en)
CA (1) CA1305284C (en)
DE (1) DE3852116T2 (en)
DK (1) DK322188A (en)
ES (1) ES2065911T3 (en)
IE (1) IE66334B1 (en)
NO (1) NO882635L (en)
NZ (1) NZ225032A (en)
ZA (1) ZA884212B (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU607988B2 (en) * 1987-04-21 1991-03-21 Southern Cross Biotech Pty Ltd. Production of proteins in active forms
EP0295859B1 (en) * 1987-06-15 1994-11-17 Southern Cross Biotech Pty.Ltd. Production of proteins in active forms
US5102989A (en) * 1991-03-15 1992-04-07 Merck & Co., Inc. Method of stabilizing recombinant hepatitis B virus surface proteins from recombinant host cells
US5252216A (en) * 1992-03-24 1993-10-12 Smithkline Beecham Corporation Protein purification
JPH0774232B2 (en) * 1992-08-31 1995-08-09 農林水産省食品総合研究所長 Novel method for protein purification using detergents
JP3279362B2 (en) * 1992-10-05 2002-04-30 井上 聰一 Diabetes judgment method and diabetes judgment device
JP3319812B2 (en) * 1993-04-05 2002-09-03 井上 聰一 Rheumatism determination method and rheumatism determination device
US20030190307A1 (en) * 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
US7153943B2 (en) * 1997-07-14 2006-12-26 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins, and methods of use thereof
ES2361190T3 (en) 1998-08-06 2011-06-14 Mountain View Pharmaceuticals, Inc. CONJUGATES OF PEG-OXIDASA DE URATO AND ITS USE.
IL152804A0 (en) * 2000-05-16 2003-06-24 Bolder Biotechnology Inc Methods for refolding proteins containing free cysteine residues
CA2497560A1 (en) * 2002-09-20 2004-04-01 Promega Corporation Luminescence-based methods and probes for measuring cytochrome p450 activity
WO2004042003A2 (en) * 2002-11-01 2004-05-21 Promega Corporation Cell lysis compositions, methods of use, apparatus, and kit
DE10309691B4 (en) 2003-02-28 2018-10-04 Hans-Knöll-Institut für Naturstoff-Forschung e.V. Recovery of soluble proteins from the biomass of recombinant microorganisms
US20040180445A1 (en) * 2003-03-12 2004-09-16 Domanico Michael J. Methods and compositions for purification of nucleic acid from a host cell
CZ2007695A3 (en) 2005-04-11 2008-02-27 Savient Pharmaceuticals, Inc. Variant forms of urate oxidase and use thereof
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
US20080159976A1 (en) * 2005-04-11 2008-07-03 Jacob Hartman Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
WO2006110761A2 (en) 2005-04-11 2006-10-19 Savient Pharmaceuticals, Inc. A variant form of urate oxidase and use thereof
WO2006125452A1 (en) * 2005-05-23 2006-11-30 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
EP2272973B1 (en) * 2005-05-31 2015-05-27 Promega Corporation Luminogenic and fluorogenic compounds and methods to detect molecules or conditions
HU230758B1 (en) * 2006-04-12 2018-03-28 Crealta Pharmaceuticals LLC 100% Purification of proteins with cationic surfactant
WO2008076933A2 (en) 2006-12-14 2008-06-26 Bolder Biotechnology, Inc. Long acting proteins and peptides and methods of making and using the same
US8288559B2 (en) * 2008-08-18 2012-10-16 Promega Corporation Luminogenic compounds and methods to detect cytochrome P450 3A enzymes
GB0901434D0 (en) * 2009-01-29 2009-03-11 Univ Strathclyde Ballast water treatment system
SG176897A1 (en) 2009-06-25 2012-01-30 Savient Pharmaceuticals Inc Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
EP2571487B1 (en) 2010-05-21 2023-01-04 Siemens Healthcare Diagnostics Inc. Zwitterionic reagents
CN102965317A (en) * 2012-11-27 2013-03-13 江南大学 Method for screening taurine strains and method for producing taurine through fermenting strains
WO2015116867A1 (en) 2014-01-29 2015-08-06 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
EP3172332B1 (en) * 2014-07-22 2020-10-14 Bio-rad Laboratories, Inc. Buffers for use with polymerases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476049A (en) * 1983-09-20 1984-10-09 Hoffmann-La Roche Inc. Method for the extraction of immune interferon
US4677196A (en) * 1985-09-06 1987-06-30 International Minerals & Chemical Corp. Purification and activation of proteins from insoluble inclusion bodies
US4681761A (en) * 1985-10-24 1987-07-21 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine
AU597924B2 (en) * 1985-12-11 1990-06-14 Natinco Nv Solubilization of protein aggregates
AU612133B2 (en) * 1987-02-20 1991-07-04 Natinco Nv Production of proteins in active forms
AU607988B2 (en) * 1987-04-21 1991-03-21 Southern Cross Biotech Pty Ltd. Production of proteins in active forms

Also Published As

Publication number Publication date
DE3852116D1 (en) 1994-12-22
ES2065911T3 (en) 1995-03-01
NZ225032A (en) 1991-02-26
ZA884212B (en) 1989-03-29
CA1305284C (en) 1992-07-14
AU1763288A (en) 1988-12-15
KR900000380A (en) 1990-01-30
DE3852116T2 (en) 1995-03-30
CN88103725A (en) 1988-12-28
AU609824B2 (en) 1991-05-09
IE66334B1 (en) 1995-12-27
DK322188D0 (en) 1988-06-14
NO882635D0 (en) 1988-06-15
JPS6447389A (en) 1989-02-21
KR0126767B1 (en) 1997-12-29
NO882635L (en) 1988-12-19
CN1032425C (en) 1996-07-31
DK322188A (en) 1988-12-17
US4992531A (en) 1991-02-12
IE881815L (en) 1988-12-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee