ATE110279T1 - Verfahren zur herstellung eines pertussis-toxin- toxoides. - Google Patents

Verfahren zur herstellung eines pertussis-toxin- toxoides.

Info

Publication number
ATE110279T1
ATE110279T1 AT89122006T AT89122006T ATE110279T1 AT E110279 T1 ATE110279 T1 AT E110279T1 AT 89122006 T AT89122006 T AT 89122006T AT 89122006 T AT89122006 T AT 89122006T AT E110279 T1 ATE110279 T1 AT E110279T1
Authority
AT
Austria
Prior art keywords
pertussis toxin
toxoide
production
toxoid
treatment
Prior art date
Application number
AT89122006T
Other languages
English (en)
Inventor
Akihiro Ginnaga
Kazunori Morokuma
Katsutoshi Aihara
Mitsuo Sakoh
Original Assignee
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeut Res Inst filed Critical Chemo Sero Therapeut Res Inst
Application granted granted Critical
Publication of ATE110279T1 publication Critical patent/ATE110279T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT89122006T 1988-11-29 1989-11-29 Verfahren zur herstellung eines pertussis-toxin- toxoides. ATE110279T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63303767A JP2706792B2 (ja) 1988-11-29 1988-11-29 百日咳毒素のトキソイド化法

Publications (1)

Publication Number Publication Date
ATE110279T1 true ATE110279T1 (de) 1994-09-15

Family

ID=17925036

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89122006T ATE110279T1 (de) 1988-11-29 1989-11-29 Verfahren zur herstellung eines pertussis-toxin- toxoides.

Country Status (6)

Country Link
US (1) US4996299A (de)
EP (1) EP0377114B1 (de)
JP (1) JP2706792B2 (de)
AT (1) ATE110279T1 (de)
CA (1) CA2004206C (de)
DE (1) DE68917709T2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5165927A (en) * 1986-08-01 1992-11-24 University Of Southern California Composition with modified pertussis toxin
US5332583A (en) * 1987-11-24 1994-07-26 Connaught Laboratories Limited Vaccine containing genetically-detoxified pertussis holotoxin
US5578308A (en) * 1990-02-12 1996-11-26 Capiau; Carine Glutaraldehyde and formalin detoxified bordetella toxin vaccine
GB9021004D0 (en) * 1990-09-27 1990-11-07 Wellcome Found Acellular vaccines
GB9216351D0 (en) * 1992-07-31 1992-09-16 Wellcome Found Vaccine production
BRPI0402630B8 (pt) * 2004-07-05 2021-05-25 Fund Butantan processo de obtenção de vacina pertussis celular menos reatogênica
WO2007111326A1 (ja) * 2006-03-27 2007-10-04 The Kitasato Institute 長期保存においても毒性復帰がおこらない特徴を持つ全菌体細菌ワクチンならびにその用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5750925A (en) * 1980-09-12 1982-03-25 Takeda Chem Ind Ltd Preparation of pertussis toxoid
CA1213234A (en) * 1983-03-30 1986-10-28 Akihiro Ginnaga Method for the production of ha fraction containing protective antigens of bordetella pertussis and pertussis vaccine
KR890001003B1 (ko) * 1984-07-19 1989-04-18 자이단 호오진 까가꾸 오요비 겟세이 료오호 겐뀨쇼 Lpf-ha의 정제방법
GB8512972D0 (en) * 1985-05-22 1985-06-26 Univ Glasgow Vaccine production
GB8601279D0 (en) * 1986-01-20 1986-02-26 Public Health Lab Service Purification of pertussis antigens
FR2597344B1 (fr) * 1986-04-16 1989-06-23 Merieux Inst Perfectionnement au procede de purification d'antigenes proteiques de bacteries appartenant au genre bordetella, en vue de l'obtention d'un vaccin acellulaire.
US4762710A (en) * 1986-06-16 1988-08-09 The United States Of America As Represented By The Department Of Health And Human Services Novel method of preparing toxoid by oxidation and metal ions
US4845036A (en) * 1987-02-03 1989-07-04 The United States Of America As Represented By The Department Of Health And Human Services Process for isolation of the B oligomer of pertussis toxin
CA1337859C (en) * 1987-04-24 1996-01-02 Masashi Chazono Method for culturing bordetella pertussis, a pertussis toxoid and a pertussis vaccine

Also Published As

Publication number Publication date
CA2004206A1 (en) 1990-05-29
CA2004206C (en) 2000-02-08
EP0377114B1 (de) 1994-08-24
EP0377114A1 (de) 1990-07-11
JPH02149529A (ja) 1990-06-08
DE68917709D1 (de) 1994-09-29
US4996299A (en) 1991-02-26
JP2706792B2 (ja) 1998-01-28
DE68917709T2 (de) 1995-05-04

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Legal Events

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