ATE10836T1 - Peptide und ihre anwendung in der therapeutik. - Google Patents
Peptide und ihre anwendung in der therapeutik.Info
- Publication number
- ATE10836T1 ATE10836T1 AT81401263T AT81401263T ATE10836T1 AT E10836 T1 ATE10836 T1 AT E10836T1 AT 81401263 T AT81401263 T AT 81401263T AT 81401263 T AT81401263 T AT 81401263T AT E10836 T1 ATE10836 T1 AT E10836T1
- Authority
- AT
- Austria
- Prior art keywords
- radical
- residue
- group
- carbon atoms
- chain
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- -1 beta OH Leu Chemical compound 0.000 abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000001153 fluoro group Chemical group F* 0.000 abstract 3
- 150000003254 radicals Chemical class 0.000 abstract 3
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical group [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UKAUYVFTDYCKQA-UHFFFAOYSA-N -2-Amino-4-hydroxybutanoic acid Natural products OC(=O)C(N)CCO UKAUYVFTDYCKQA-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- UKAUYVFTDYCKQA-VKHMYHEASA-N L-homoserine Chemical compound OC(=O)[C@@H](N)CCO UKAUYVFTDYCKQA-VKHMYHEASA-N 0.000 abstract 1
- ROHDXJUFQVRDAV-UWVGGRQHSA-N Phe-Ser Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@@H](N)CC1=CC=CC=C1 ROHDXJUFQVRDAV-UWVGGRQHSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- OWIUPIRUAQMTTK-UHFFFAOYSA-N carbazic acid Chemical compound NNC(O)=O OWIUPIRUAQMTTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 108010051242 phenylalanylserine Proteins 0.000 abstract 1
- 150000008104 phosphatidylethanolamines Chemical group 0.000 abstract 1
- 230000000506 psychotropic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/67—Lipotropins, e.g. beta, gamma lipotropin
- C07K14/672—Lipotropins, e.g. beta, gamma lipotropin with at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/70—Enkephalins
- C07K14/702—Enkephalins with at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8017523A FR2488253A1 (fr) | 1980-08-08 | 1980-08-08 | Nouveaux peptides et leur application en therapeutique |
| EP81401263A EP0046113B1 (fr) | 1980-08-08 | 1981-08-05 | Nouveaux peptides et leur application en thérapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE10836T1 true ATE10836T1 (de) | 1985-01-15 |
Family
ID=9245026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT81401263T ATE10836T1 (de) | 1980-08-08 | 1981-08-05 | Peptide und ihre anwendung in der therapeutik. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4407794A (OSRAM) |
| EP (1) | EP0046113B1 (OSRAM) |
| JP (1) | JPS5759845A (OSRAM) |
| AT (1) | ATE10836T1 (OSRAM) |
| CA (1) | CA1292344C (OSRAM) |
| DE (1) | DE3167826D1 (OSRAM) |
| FR (1) | FR2488253A1 (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5516891A (en) * | 1992-06-16 | 1996-05-14 | Kinerton, Ltd. | Liquid phase synthesis of peptides and peptide derivatives |
| US6190691B1 (en) | 1994-04-12 | 2001-02-20 | Adolor Corporation | Methods for treating inflammatory conditions |
| US5962477A (en) * | 1994-04-12 | 1999-10-05 | Adolor Corporation | Screening methods for cytokine inhibitors |
| US5849761A (en) | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
| US6573282B1 (en) | 1995-09-12 | 2003-06-03 | Adolor Corporation | Peripherally active anti-hyperalgesic opiates |
| US6262117B1 (en) | 1999-02-18 | 2001-07-17 | Allergan Sales, Inc. | Method and composition for treating acne |
| FR2823212B1 (fr) * | 2001-04-10 | 2005-12-02 | Inst Nat Sante Rech Med | Inhibiteurs de la toxine botulique de type b |
| JP2006518759A (ja) * | 2003-02-25 | 2006-08-17 | ザ アリゾナ ボード オブ リージェンツ オン ビハーフ オブ ザ ユニヴァーシティ オブ アリゾナ | グリコシル化エンケファリン薬 |
| ATE399763T1 (de) * | 2003-05-30 | 2008-07-15 | Prozymex As | Proteasehemmer |
| US20050019422A1 (en) * | 2003-07-23 | 2005-01-27 | Allergan, Inc. | Method and composition for treating acne |
| AR049938A1 (es) * | 2004-06-25 | 2006-09-13 | Takeda Pharmaceutical | Derivados de metastina y utilizacion de los mismos |
| EP2197470A2 (en) * | 2007-09-11 | 2010-06-23 | Mondobiotech Laboratories AG | Use of bubuc and optionally eaa-mart1 (26-35) as a therapeutic agent for the treatment of hcmv infections |
| FR2931151A1 (fr) * | 2008-05-13 | 2009-11-20 | Pharmaleads Soc Par Actions Si | Nouveaux derives d'amino-acides, leur procede de preparation et leur utilisation therapeutique |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK33177A (da) * | 1976-01-26 | 1977-07-27 | Wellcome Found | Fremgangsmade til fremstilling af peptider |
| NZ183712A (en) * | 1976-04-08 | 1979-10-25 | Ici Ltd | Polypeptide analogues of enkephalins, and pharmaceutical compositions |
| US4261888A (en) * | 1976-04-12 | 1981-04-14 | Sandoz Ltd. | Organic compounds |
| US4259234A (en) * | 1976-09-27 | 1981-03-31 | Eli Lilly And Company | Analgesic compounds |
| US4322342A (en) * | 1977-06-20 | 1982-03-30 | Eli Lilly And Company | Analgesic compounds |
| US4196122A (en) * | 1977-07-01 | 1980-04-01 | American Home Products Corporation | Analgesic polypeptide |
| GB1604644A (en) * | 1977-07-22 | 1981-12-09 | Wellcome Found | Biologically active pentapeptide amides |
| US4264491A (en) * | 1977-10-03 | 1981-04-28 | Eli Lilly And Company | Analgesic compounds |
| US4331593A (en) * | 1977-10-03 | 1982-05-25 | Smithwick Jr Edward L | Analgesic compounds |
| US4213968A (en) * | 1978-06-05 | 1980-07-22 | Coy David Howard | Enkephalin derivatives |
| US4278596A (en) * | 1978-08-08 | 1981-07-14 | American Home Products Corporation | Analgesic pentapeptides |
| US4247543A (en) * | 1979-04-09 | 1981-01-27 | Sandoz Ltd. | Organic compounds |
| US4216127A (en) * | 1979-07-05 | 1980-08-05 | American Home Products Corporation | Enkephalin analogues |
| US4283329A (en) * | 1979-12-17 | 1981-08-11 | Eli Lilly And Company | Pharmacologically active peptides |
| US4322339A (en) * | 1980-10-20 | 1982-03-30 | Eli Lilly And Company | Pharmacologically active peptides |
| US4309343A (en) * | 1980-11-25 | 1982-01-05 | Eli Lilly And Company | Pharmacologically active peptides |
-
1980
- 1980-08-08 FR FR8017523A patent/FR2488253A1/fr active Granted
-
1981
- 1981-08-03 US US06/289,383 patent/US4407794A/en not_active Expired - Fee Related
- 1981-08-05 DE DE8181401263T patent/DE3167826D1/de not_active Expired
- 1981-08-05 AT AT81401263T patent/ATE10836T1/de not_active IP Right Cessation
- 1981-08-05 EP EP81401263A patent/EP0046113B1/fr not_active Expired
- 1981-08-06 CA CA000383284A patent/CA1292344C/en not_active Expired - Lifetime
- 1981-08-07 JP JP56123927A patent/JPS5759845A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US4407794A (en) | 1983-10-04 |
| EP0046113B1 (fr) | 1984-12-19 |
| DE3167826D1 (en) | 1985-01-31 |
| EP0046113A1 (fr) | 1982-02-17 |
| JPS5759845A (en) | 1982-04-10 |
| CA1292344C (en) | 1991-11-19 |
| FR2488253B1 (OSRAM) | 1984-01-27 |
| FR2488253A1 (fr) | 1982-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |