ATE102255T1 - METHOD FOR THE SEPARATION OF HYDROXY-CYCLOPENTENONES USING A LIPASE AND TRANSACYLATING AGENTS. - Google Patents

METHOD FOR THE SEPARATION OF HYDROXY-CYCLOPENTENONES USING A LIPASE AND TRANSACYLATING AGENTS.

Info

Publication number
ATE102255T1
ATE102255T1 AT89115956T AT89115956T ATE102255T1 AT E102255 T1 ATE102255 T1 AT E102255T1 AT 89115956 T AT89115956 T AT 89115956T AT 89115956 T AT89115956 T AT 89115956T AT E102255 T1 ATE102255 T1 AT E102255T1
Authority
AT
Austria
Prior art keywords
transacylating
cyclopentenones
lipase
hydroxy
agents
Prior art date
Application number
AT89115956T
Other languages
German (de)
Inventor
Chi-Huey Wong
Yi-Fong Wang
William J Hennen
Kevin Anthony Babiak
John H Dygos
John S Ng
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/396,723 external-priority patent/US5106750A/en
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of ATE102255T1 publication Critical patent/ATE102255T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
AT89115956T 1988-08-30 1989-08-30 METHOD FOR THE SEPARATION OF HYDROXY-CYCLOPENTENONES USING A LIPASE AND TRANSACYLATING AGENTS. ATE102255T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23835888A 1988-08-30 1988-08-30
US07/396,723 US5106750A (en) 1988-08-30 1989-08-24 Enantio- and regioselective synthesis of organic compounds using enol esters as irreversible transacylation reagents
EP89115956A EP0357009B1 (en) 1988-08-30 1989-08-30 Method of resolution of hydroxy-cyclopentenones using a lipase and transacylation agents

Publications (1)

Publication Number Publication Date
ATE102255T1 true ATE102255T1 (en) 1994-03-15

Family

ID=27232456

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89115956T ATE102255T1 (en) 1988-08-30 1989-08-30 METHOD FOR THE SEPARATION OF HYDROXY-CYCLOPENTENONES USING A LIPASE AND TRANSACYLATING AGENTS.

Country Status (2)

Country Link
AT (1) ATE102255T1 (en)
GR (1) GR3033718T3 (en)

Also Published As

Publication number Publication date
GR3033718T3 (en) 2000-10-31

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee