ATA992A - (6,7-SUBSTITUTED-8-ALKOXY-1-CYCLOPROPYL-1,4- - Google Patents

(6,7-SUBSTITUTED-8-ALKOXY-1-CYCLOPROPYL-1,4-

Info

Publication number
ATA992A
ATA992A AT0000992A AT992A ATA992A AT A992 A ATA992 A AT A992A AT 0000992 A AT0000992 A AT 0000992A AT 992 A AT992 A AT 992A AT A992 A ATA992 A AT A992A
Authority
AT
Austria
Prior art keywords
cyclopropyl
alkoxy
substituted
Prior art date
Application number
AT0000992A
Other languages
German (de)
Other versions
AT397656B (en
Original Assignee
Kyorin Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2178765A priority Critical patent/JPH0778065B2/en
Priority to US07/724,164 priority patent/US5157117A/en
Priority to KR1019910011229A priority patent/KR960002273B1/en
Priority to ES91111139T priority patent/ES2137154T3/en
Priority to DE69131636T priority patent/DE69131636T2/en
Priority to EP91111139A priority patent/EP0464823B1/en
Priority to HU2279/91A priority patent/HU215429B/en
Priority to AU80263/91A priority patent/AU646055B2/en
Priority to CA002046361A priority patent/CA2046361C/en
Priority to CN91104666A priority patent/CN1031795C/en
Priority to LU88049A priority patent/LU88049A1/en
Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk
Priority to AT0000992A priority patent/AT397656B/en
Publication of ATA992A publication Critical patent/ATA992A/en
Application granted granted Critical
Publication of AT397656B publication Critical patent/AT397656B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/04—Esters of boric acids
AT0000992A 1990-07-06 1992-01-07 (6,7-SUBSTITUTED-8-ALKOXY-1-CYCLOPROPYL-1,4- AT397656B (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
JP2178765A JPH0778065B2 (en) 1990-07-06 1990-07-06 (6,7-Substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid-O ▲ above 3 ▼, O ▲ above 4) bis (acyloxy-O) Boron compound, salt thereof, and method for producing the same
US07/724,164 US5157117A (en) 1990-07-06 1991-07-01 (6,7)-substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid-03,04) bis (acyloxy-0) borate and the salt thereof, and the preparing method of the same
KR1019910011229A KR960002273B1 (en) 1990-07-06 1991-07-03 6,7-substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinoline
EP91111139A EP0464823B1 (en) 1990-07-06 1991-07-04 (6,7-Substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid-O3,O4)bis(acyloxy-O)borates and the salts thereof, and methods for their manufacture
ES91111139T ES2137154T3 (en) 1990-07-06 1991-07-04 BORATES BIS- (ACILOXI-O) ACID (6,7-SUBSTITUTED-8-ALCOXI-1-CICLOPROPIL-1,4-DIHIDRO-4-OXO-3-QUINOLINOCARBOXILICO-O3, O4 AND ITS SALTS, AND PREPARATION.
DE69131636T DE69131636T2 (en) 1990-07-06 1991-07-04 (6,7-substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid-03.04) -bis (acyloxy-0) -borates and their salts and methods for their preparation
HU2279/91A HU215429B (en) 1990-07-06 1991-07-05 Process for producing ((6,7-substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolin-carboxylic acid)-0 upper 3, 0 upper 4-bis(acyl-oxy)-borate and salts
AU80263/91A AU646055B2 (en) 1990-07-06 1991-07-05 (6,7-substituted-8-alkoxy-1-cyclopropyl-1,4- dihydro-4-oxo-3-quinolinecarboxylic acid-03,04)bis(acyloxy-0) borate and the salt thereof, and the preparing method of the same
CA002046361A CA2046361C (en) 1990-07-06 1991-07-05 (6,7-substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid-03,04) bis (acyloxy-0) borate, salts and hydrates thereof
CN91104666A CN1031795C (en) 1990-07-06 1991-07-06 6,7-substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid-0 3,0 4, bis(acyloxy-o) borate
LU88049A LU88049A1 (en) 1990-07-06 1992-01-03 BIS (ACYLOXY-O) BORATE (ACID-O3, O4-6,7-SUBSTITUE-8-ALCOXY-L-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-3-QUINOLEINECARBOXYLIC AND SALT THEREOF , AS WELL AS THEIR PREPARATION PROCESS
AT0000992A AT397656B (en) 1990-07-06 1992-01-07 (6,7-SUBSTITUTED-8-ALKOXY-1-CYCLOPROPYL-1,4-

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2178765A JPH0778065B2 (en) 1990-07-06 1990-07-06 (6,7-Substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid-O ▲ above 3 ▼, O ▲ above 4) bis (acyloxy-O) Boron compound, salt thereof, and method for producing the same
AT0000992A AT397656B (en) 1990-07-06 1992-01-07 (6,7-SUBSTITUTED-8-ALKOXY-1-CYCLOPROPYL-1,4-

Publications (2)

Publication Number Publication Date
ATA992A true ATA992A (en) 1993-10-15
AT397656B AT397656B (en) 1994-06-27

Family

ID=25591090

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0000992A AT397656B (en) 1990-07-06 1992-01-07 (6,7-SUBSTITUTED-8-ALKOXY-1-CYCLOPROPYL-1,4-

Country Status (12)

Country Link
US (1) US5157117A (en)
EP (1) EP0464823B1 (en)
JP (1) JPH0778065B2 (en)
KR (1) KR960002273B1 (en)
CN (1) CN1031795C (en)
AT (1) AT397656B (en)
AU (1) AU646055B2 (en)
CA (1) CA2046361C (en)
DE (1) DE69131636T2 (en)
ES (1) ES2137154T3 (en)
HU (1) HU215429B (en)
LU (1) LU88049A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR910100517A (en) * 1991-12-30 1993-08-31 Kyorin Seiyaku Kk (6,7-substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid-03,04) bis (acyloxy-0)
EP0677522A4 (en) * 1992-12-28 1995-12-27 Yoshitomi Pharmaceutical 8-methoxyquinolonecarboxylic acid derivative.
CA2152828A1 (en) * 1993-03-16 1994-07-07 Shin-Ichi Uesato 8-methoxy-quinolonecarboxylic acid derivatives
ES2092963B1 (en) * 1995-04-12 1997-12-16 Sint Quimica Sa PROCEDURE FOR THE PREPARATION OF ACID 1-CICLOPROPIL-6-FLUORO-1, 4-DIHIDRO-7- (1S, 4S) -5-METHYL-2,5-DIAZABICICLO (2.2.1) HEPT-2-IL) -4 -OXO-3-QUINOLINCARBOXILICO AND ITS SALTS.
WO2004069825A1 (en) * 2002-08-14 2004-08-19 Teva Pharmaceutical Industries Ltd. Synthesis of gatifloxacin
WO2005009970A1 (en) * 2003-07-28 2005-02-03 Matrix Laboratories Ltd An improved process for the preparation of gatifloxacin
EP1651630A1 (en) * 2003-08-05 2006-05-03 Matrix Laboratories Ltd An improved process for the preparation of moxifloxacin hydrochloride
ES2232309B1 (en) * 2003-11-13 2006-08-01 Quimica Sintetica, S.A. SIMPLIFIED PROCEDURE FOR OBTAINING GATIFLOXACINO.
US7781585B2 (en) 2004-06-04 2010-08-24 Matrix Laboratories Ltd Crystalline forms of Gatifloxacin
EP2161269A1 (en) * 2005-06-15 2010-03-10 Hetero Drugs Limited Process for the preparation of amorphous gemifloxacin
US7456279B2 (en) 2006-03-28 2008-11-25 The Procter & Gamble Company Coupling process for preparing quinolone intermediates
BRPI0709772B8 (en) * 2006-03-28 2021-05-25 The Protecter & Gamble Company malate salts and polymorphs of (3s,5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
CN101045724B (en) * 2006-03-28 2011-08-17 宝洁公司 Coupling method for preparing quinolone intermediate
IN2014MN02582A (en) * 2006-11-13 2015-09-11 Cipla Ltd
CN102617622B (en) * 2011-01-31 2016-06-15 深圳信立泰药业股份有限公司 A kind of prepare Moxifloxacin or the method for its pharmacologically acceptable salt and intermediate thereof
CN102351858B (en) * 2011-09-21 2013-03-27 浙江新东港药业股份有限公司 High selectivity method for synthesizing moxifloxacin
EP2928892B1 (en) 2012-12-04 2018-03-21 Mankind Pharma Ltd. An improved process for the preparation of moxifloxacin hydrochloride
CN103739547B (en) * 2014-01-03 2015-09-02 沈阳药科大学 The synthetic method of 2-[6-methoxyl group-3-(2,3-dichlorophenyl) methyl-4-oxo-Isosorbide-5-Nitrae-dihydro-1 (4H)-quinolyl] acetic acid
CN104031078A (en) * 2014-05-28 2014-09-10 成都克莱蒙医药科技有限公司 Synthesis method of moxifloxacin hydrochloride intermediate
KR102184814B1 (en) * 2019-05-23 2020-11-30 재단법인 한국탄소융합기술원 Epoxy resin composition having improved adhesion and fiber-rubber composite connecting material using the same
CN111233858B (en) * 2020-03-23 2022-05-24 常州方圆制药有限公司 Preparation method of moxifloxacin hydrochloride
CN111777632A (en) * 2020-07-20 2020-10-16 浙江国邦药业有限公司 Preparation method of moxifloxacin hydrochloride chelate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3705621C2 (en) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclic substituted quinolonecarboxylic acid derivatives
EP0241206A3 (en) * 1986-03-31 1989-05-10 Sankyo Company Limited Quinoline-3-carboxylic acid derivatives, their preparation and use
JPS63198664A (en) * 1986-03-31 1988-08-17 Sankyo Co Ltd Quinolonecarboxylic acid derivative
HU198709B (en) * 1987-04-08 1989-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing quinoline-carboxylic acid derivatives
YU46451B (en) * 1987-04-08 1993-10-20 Chinoin Gyogyszer Es Vegyeszeti Ter Mekek Gyara Rt. PROCESS FOR PREPARATION OF MIXED ANHYDRIDS OF QUINOLINE-CARBOXYL AND BORIC ACID

Also Published As

Publication number Publication date
HUT58747A (en) 1992-03-30
AT397656B (en) 1994-06-27
EP0464823A1 (en) 1992-01-08
CN1059527A (en) 1992-03-18
CN1031795C (en) 1996-05-15
DE69131636D1 (en) 1999-10-28
CA2046361A1 (en) 1992-01-07
CA2046361C (en) 1999-07-20
DE69131636T2 (en) 2000-05-04
US5157117A (en) 1992-10-20
KR960002273B1 (en) 1996-02-14
AU646055B2 (en) 1994-02-03
HU215429B (en) 1999-04-28
ES2137154T3 (en) 1999-12-16
JPH0469388A (en) 1992-03-04
KR920002615A (en) 1992-02-28
EP0464823B1 (en) 1999-09-22
AU8026391A (en) 1993-01-28
HU912279D0 (en) 1991-12-30
JPH0778065B2 (en) 1995-08-23
LU88049A1 (en) 1992-08-25

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Effective date: 20120107