ATA73587A - METHOD FOR PRODUCING ALKYLAMINOFURANONE DERIVATIVES AND THEIR THERAPEUTICALLY ACCEPTABLE SALTS - Google Patents

METHOD FOR PRODUCING ALKYLAMINOFURANONE DERIVATIVES AND THEIR THERAPEUTICALLY ACCEPTABLE SALTS

Info

Publication number
ATA73587A
ATA73587A AT0073587A AT73587A ATA73587A AT A73587 A ATA73587 A AT A73587A AT 0073587 A AT0073587 A AT 0073587A AT 73587 A AT73587 A AT 73587A AT A73587 A ATA73587 A AT A73587A
Authority
AT
Austria
Prior art keywords
alkylaminofuranone
derivatives
producing
acceptable salts
general formula
Prior art date
Application number
AT0073587A
Other languages
German (de)
Other versions
AT398424B (en
Inventor
Janos Dr Fischer
Laszlo Dipl Chem Ing Dobay
Tamas Dr Fodor
Bela Dr Stefko
Bela Kiss
Zsolt Dr Szombathelyi
Egon Dr Karpati
Istvan Dr Laszlovszky
Laszlo Dr Szporny
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ATA73587A publication Critical patent/ATA73587A/en
Application granted granted Critical
Publication of AT398424B publication Critical patent/AT398424B/en

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

To prepare alkylaminofuranone derivatives of the general formula I in which R is hydrogen or a protective group which is compatible with the peptide linkage, a dipeptide or dipeptide ester of general formula V is reacted with a novel (-)-methyl butenoate of the formula IV, the resulting novel compound is cyclized in a known manner in a strong inorganic acid as reaction medium to give the alkylaminofuranone derivatives of the general formula I and, where appropriate, the protective group is eliminated with a strong inorganic acid in a manner known per se. <IMAGE>
AT0073587A 1986-04-01 1987-03-26 Process for the preparation of alkylaminofuranone derivatives and their therapeutically acceptable salts AT398424B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU861333A HU194912B (en) 1986-04-01 1986-04-01 Process for producing alkylamino-furanone-dipeptide derivatives and acid additional salts thereof

Publications (2)

Publication Number Publication Date
ATA73587A true ATA73587A (en) 1994-04-15
AT398424B AT398424B (en) 1994-12-27

Family

ID=10953974

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0073587A AT398424B (en) 1986-04-01 1987-03-26 Process for the preparation of alkylaminofuranone derivatives and their therapeutically acceptable salts

Country Status (6)

Country Link
AT (1) AT398424B (en)
ES (1) ES2004706A6 (en)
HU (1) HU194912B (en)
IT (1) IT1204952B (en)
PL (1) PL148181B1 (en)
PT (1) PT84557B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU192914B (en) * 1985-02-11 1987-07-28 Richter Gedeon Vegyeszet Process for producing new 3-/substituted amino/-5-phenyl-2/3h/-furanone derivatives and pharmaceutically acceptable salts

Also Published As

Publication number Publication date
PT84557B (en) 1989-11-30
PL264836A1 (en) 1988-04-14
HUT43621A (en) 1987-11-30
AT398424B (en) 1994-12-27
HU194912B (en) 1988-03-28
IT1204952B (en) 1989-03-10
IT8719801A0 (en) 1987-03-23
PL148181B1 (en) 1989-09-30
ES2004706A6 (en) 1989-02-01
PT84557A (en) 1987-04-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
ELJ Ceased due to non-payment of the annual fee
REN Ceased due to non-payment of the annual fee