ATA110775A - PROCESS FOR THE PRODUCTION OF NEW SUBSTITUTED BENZYLAMINES AND THEIR SALTS - Google Patents

PROCESS FOR THE PRODUCTION OF NEW SUBSTITUTED BENZYLAMINES AND THEIR SALTS

Info

Publication number
ATA110775A
ATA110775A AT110775*1A AT110771A ATA110775A AT A110775 A ATA110775 A AT A110775A AT 110771 A AT110771 A AT 110771A AT A110775 A ATA110775 A AT A110775A
Authority
AT
Austria
Prior art keywords
salts
production
new substituted
substituted benzylamines
benzylamines
Prior art date
Application number
AT110775*1A
Other languages
German (de)
Other versions
AT300779B (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1383069A external-priority patent/CH574921A5/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of AT300779B publication Critical patent/AT300779B/en
Publication of ATA110775A publication Critical patent/ATA110775A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2632-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/272-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4042,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02Preparation by ring-closure or hydrogenation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT110771A 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts AT300779B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80834369A 1969-03-18 1969-03-18
US84324469A 1969-07-18 1969-07-18
CH1383069A CH574921A5 (en) 1969-09-12 1969-09-12 Anti-inflammatory alpha-aminophenyl carboxylic acids

Publications (2)

Publication Number Publication Date
AT300779B AT300779B (en) 1972-08-10
ATA110775A true ATA110775A (en) 1975-05-15

Family

ID=27177059

Family Applications (13)

Application Number Title Priority Date Filing Date
AT110171A AT299931B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110071A AT299930B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110671A AT301529B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT109971A AT299929B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT109871A AT299928B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110271A AT299932B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT02476/70A AT299183B (en) 1969-03-18 1970-03-17 PROCESS FOR PRODUCING NEW HEROCYCLIC COMPOUNDS AND THEIR SALT
AT110371A AT299933B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110871A AT301530B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110571A AT299935B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110771A AT300779B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110471A AT299934B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT109771A AT299927B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts

Family Applications Before (10)

Application Number Title Priority Date Filing Date
AT110171A AT299931B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110071A AT299930B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110671A AT301529B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT109971A AT299929B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT109871A AT299928B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110271A AT299932B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT02476/70A AT299183B (en) 1969-03-18 1970-03-17 PROCESS FOR PRODUCING NEW HEROCYCLIC COMPOUNDS AND THEIR SALT
AT110371A AT299933B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110871A AT301530B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT110571A AT299935B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT110471A AT299934B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts
AT109771A AT299927B (en) 1969-03-18 1970-03-17 Process for the preparation of new heterocyclic compounds and their salts

Country Status (13)

Country Link
JP (13) JPS5330711B1 (en)
AR (14) AR192553A1 (en)
AT (13) AT299931B (en)
BG (6) BG17522A3 (en)
CS (12) CS181673B2 (en)
CY (1) CY810A (en)
IE (1) IE33749B1 (en)
KE (1) KE2543A (en)
MY (1) MY7500151A (en)
OA (1) OA03436A (en)
PL (2) PL116497B1 (en)
RO (7) RO61544A (en)
YU (13) YU212682A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5792413U (en) * 1980-11-28 1982-06-07
JPS57110494A (en) * 1980-12-29 1982-07-09 Fujitsu Ltd Stacker device for form

Also Published As

Publication number Publication date
YU212682A (en) 1983-10-31
RO62995A (en) 1978-05-15
JPS5339431B1 (en) 1978-10-21
CS181676B2 (en) 1978-03-31
AR194392A1 (en) 1973-07-13
YU213782A (en) 1983-10-31
RO61512A (en) 1977-01-15
CY810A (en) 1976-12-01
YU212482A (en) 1983-10-31
AR194393A1 (en) 1973-07-13
YU213282A (en) 1983-10-31
AR194394A1 (en) 1973-07-13
AT300779B (en) 1972-08-10
BG17520A3 (en) 1973-11-10
YU212582A (en) 1983-10-31
AR195196A1 (en) 1973-09-19
YU212382A (en) 1983-10-31
YU212882A (en) 1983-10-31
AT301529B (en) 1972-09-11
IE33749L (en) 1970-09-18
CS181675B2 (en) 1978-03-31
AT299183B (en) 1972-05-15
AR196176A1 (en) 1973-11-30
JPS5330711B1 (en) 1978-08-29
BG17754A3 (en) 1973-12-25
RO62486A (en) 1978-02-15
CS181679B2 (en) 1978-03-31
CS181670B2 (en) 1978-03-31
AR199774A1 (en) 1974-09-30
BG17522A3 (en) 1973-11-10
AR194395A1 (en) 1973-07-13
RO62407A (en) 1978-03-15
RO62595A (en) 1978-05-15
JPS537429B1 (en) 1978-03-17
AT299929B (en) 1972-07-10
YU213582A (en) 1983-10-31
YU213082A (en) 1983-10-31
MY7500151A (en) 1975-12-31
AR194396A1 (en) 1973-07-13
AT299927B (en) 1972-07-10
AT299931B (en) 1972-07-10
AT299928B (en) 1972-07-10
AR194398A1 (en) 1973-07-13
PL116495B1 (en) 1981-06-30
JPS5339429B1 (en) 1978-10-21
YU212782A (en) 1983-10-31
AR197478A1 (en) 1974-04-15
CS181671B2 (en) 1978-03-31
YU213882A (en) 1983-10-31
JPS5339434B1 (en) 1978-10-21
BG17755A3 (en) 1973-12-25
JPS5341669B1 (en) 1978-11-06
YU212982A (en) 1983-10-31
AT299934B (en) 1972-07-10
AT299930B (en) 1972-07-10
BG17518A3 (en) 1973-11-10
JPS5341151B1 (en) 1978-10-31
YU213482A (en) 1983-10-31
JPS5339432B1 (en) 1978-10-21
CS181672B2 (en) 1978-03-31
CS181656B2 (en) 1978-03-31
JPS5341149B1 (en) 1978-10-31
AR195194A1 (en) 1973-09-19
AT299935B (en) 1972-07-10
CS181678B2 (en) 1978-03-31
IE33749B1 (en) 1974-10-16
KE2543A (en) 1975-07-25
RO62488A (en) 1978-03-15
AR194397A1 (en) 1973-07-13
CS181669B2 (en) 1978-03-31
CS181681B2 (en) 1978-03-31
JPS5339430B1 (en) 1978-10-21
PL116497B1 (en) 1981-06-30
CS181682B2 (en) 1978-03-31
AT299932B (en) 1972-07-10
AR192553A1 (en) 1973-02-28
CS181673B2 (en) 1978-03-31
AR201479A1 (en) 1975-03-21
OA03436A (en) 1971-03-30
RO61544A (en) 1977-01-15
BG17521A3 (en) 1973-11-10
AT301530B (en) 1972-09-11
JPS5341670B1 (en) 1978-11-06
AT299933B (en) 1972-07-10
JPS5341150B1 (en) 1978-10-31
JPS5341148B1 (en) 1978-10-31

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Legal Events

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REN Ceased due to non-payment of the annual fee