AT348678B - METHOD FOR PRODUCING THE NEW CRYSTALLINE ANHYDRATE OF SODIUM-7- (D-2-HYDROXY-2-PHENYLACETAMIDO) -3- (1- METHYL-1H-TETRAZOL-5-YL-THIOMETHYL) -3-CEPHEM-4- CARBOXYLATE - Google Patents

METHOD FOR PRODUCING THE NEW CRYSTALLINE ANHYDRATE OF SODIUM-7- (D-2-HYDROXY-2-PHENYLACETAMIDO) -3- (1- METHYL-1H-TETRAZOL-5-YL-THIOMETHYL) -3-CEPHEM-4- CARBOXYLATE

Info

Publication number
AT348678B
AT348678B AT948976A AT948976A AT348678B AT 348678 B AT348678 B AT 348678B AT 948976 A AT948976 A AT 948976A AT 948976 A AT948976 A AT 948976A AT 348678 B AT348678 B AT 348678B
Authority
AT
Austria
Prior art keywords
phenylacetamido
cephem
thiomethyl
tetrazol
carboxylate
Prior art date
Application number
AT948976A
Other languages
German (de)
Other versions
ATA948976A (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ATA948976A publication Critical patent/ATA948976A/en
Application granted granted Critical
Publication of AT348678B publication Critical patent/AT348678B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
AT948976A 1975-12-22 1976-12-21 METHOD FOR PRODUCING THE NEW CRYSTALLINE ANHYDRATE OF SODIUM-7- (D-2-HYDROXY-2-PHENYLACETAMIDO) -3- (1- METHYL-1H-TETRAZOL-5-YL-THIOMETHYL) -3-CEPHEM-4- CARBOXYLATE AT348678B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/642,922 US4054738A (en) 1975-12-22 1975-12-22 Sodium cefamandole crystalline forms

Publications (2)

Publication Number Publication Date
ATA948976A ATA948976A (en) 1978-07-15
AT348678B true AT348678B (en) 1979-02-26

Family

ID=24578600

Family Applications (2)

Application Number Title Priority Date Filing Date
AT948976A AT348678B (en) 1975-12-22 1976-12-21 METHOD FOR PRODUCING THE NEW CRYSTALLINE ANHYDRATE OF SODIUM-7- (D-2-HYDROXY-2-PHENYLACETAMIDO) -3- (1- METHYL-1H-TETRAZOL-5-YL-THIOMETHYL) -3-CEPHEM-4- CARBOXYLATE
AT217578A AT349148B (en) 1975-12-22 1976-12-21 METHOD FOR PRODUCING THE NEW CRYSTALLINE MONOHYDRATE OF SODIUM 7- (D-2-HYDROXY-2-PHENYLACETAMIDO) -3- (1-METHYL-1H-TETRAZOL-5-YL-THIOMETHYL) -3-CEPHEM-4-CARBOXYLATE

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT217578A AT349148B (en) 1975-12-22 1976-12-21 METHOD FOR PRODUCING THE NEW CRYSTALLINE MONOHYDRATE OF SODIUM 7- (D-2-HYDROXY-2-PHENYLACETAMIDO) -3- (1-METHYL-1H-TETRAZOL-5-YL-THIOMETHYL) -3-CEPHEM-4-CARBOXYLATE

Country Status (31)

Country Link
US (1) US4054738A (en)
JP (2) JPS5282714A (en)
AR (1) AR213300A1 (en)
AT (2) AT348678B (en)
AU (1) AU505924B2 (en)
BE (1) BE849415A (en)
CA (1) CA1080696A (en)
CH (1) CH628348A5 (en)
CS (1) CS195746B2 (en)
DD (1) DD128727A5 (en)
DE (1) DE2654647C2 (en)
DK (1) DK153156C (en)
FI (1) FI66008C (en)
FR (3) FR2361898A1 (en)
GB (1) GB1565854A (en)
GR (1) GR65891B (en)
HU (1) HU172474B (en)
IL (3) IL50977A (en)
LU (1) LU76435A1 (en)
MX (1) MX3840E (en)
NL (1) NL187483C (en)
NO (1) NO148887C (en)
NZ (1) NZ182694A (en)
OA (1) OA05518A (en)
PH (1) PH12191A (en)
PL (1) PL102739B1 (en)
PT (1) PT65955B (en)
RO (3) RO69709A (en)
SE (3) SE424730B (en)
SU (3) SU637087A3 (en)
ZA (1) ZA766957B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168376A (en) * 1978-06-05 1979-09-18 Eli Lilly And Company Process for crystalline sodium cefamandole
US4237279A (en) * 1979-07-27 1980-12-02 Eli Lilly And Company Crystalline 3-hydroxycephalosporin solvates
DE3313816A1 (en) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt NEW CEFTAZIDIM CRYSTAL MODIFICATION
DE3313818A1 (en) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt NEW CEFTAZIDIM CRYSTAL MODIFICATION
CA1242699A (en) * 1985-02-01 1988-10-04 Bristol-Myers Company Cefbuperazone and derivatives thereof
JPH0677412B2 (en) * 1985-05-03 1994-09-28 株式会社フジクラ Power cable for high voltage DC transmission
JPS629495U (en) * 1985-07-01 1987-01-21
GB9717629D0 (en) 1997-08-21 1997-10-22 Johnson Matthey Plc Removal of residual organic solvents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496171A (en) * 1969-02-17 1970-02-17 Lilly Co Eli Process for improving the physical and chemical properties of cephaloglycin
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
US3692781A (en) * 1971-02-26 1972-09-19 Glaxo Lab Ltd Recovery of pure cephalexin from acidic reaction mixtures
US3819620A (en) * 1972-06-01 1974-06-25 Squibb & Sons Inc 7-(d-alpha-amino-1,4-cyclohexadien-1-ylacet-amido)desacetoxycephalosporanic acid dihydrate
US3862186A (en) * 1972-12-15 1975-01-21 Bristol Myers Co Process for the production of cephalexin monohydrate
US3928592A (en) * 1974-02-22 1975-12-23 Lilly Co Eli Antibiotic pharmaceutical compositions

Also Published As

Publication number Publication date
RO75963A (en) 1981-02-28
FI763682A (en) 1977-06-23
NL187483B (en) 1991-05-16
SU671732A3 (en) 1979-06-30
PT65955B (en) 1978-06-15
SE443564B (en) 1986-03-03
CS195746B2 (en) 1980-02-29
DK153156B (en) 1988-06-20
JPS6183189A (en) 1986-04-26
NL7614233A (en) 1977-06-24
ZA766957B (en) 1978-06-28
FR2351984B1 (en) 1980-06-27
DE2654647A1 (en) 1977-06-30
BE849415A (en) 1977-06-15
IL50977A (en) 1980-02-29
FR2361898B1 (en) 1980-03-14
CH628348A5 (en) 1982-02-26
SU1018585A3 (en) 1983-05-15
ATA217578A (en) 1978-08-15
HU172474B (en) 1978-09-28
CA1080696A (en) 1980-07-01
OA05518A (en) 1981-04-30
FR2351985A1 (en) 1977-12-16
FR2351984A1 (en) 1977-12-16
NL187483C (en) 1991-10-16
JPS5282714A (en) 1977-07-11
MX3840E (en) 1981-08-11
IL57387A0 (en) 1979-09-30
PH12191A (en) 1978-11-21
SE8201701L (en) 1982-03-17
DE2654647C2 (en) 1982-06-24
DK575576A (en) 1977-06-23
LU76435A1 (en) 1977-06-10
FI66008B (en) 1984-04-30
AU505924B2 (en) 1979-12-06
JPS624393B2 (en) 1987-01-30
IL57386A0 (en) 1979-09-30
AT349148B (en) 1979-03-26
NZ182694A (en) 1978-09-25
SE8201702L (en) 1982-03-17
SE7614401L (en) 1977-06-23
NO764222L (en) 1977-06-23
PL102739B1 (en) 1979-04-30
JPS61351B2 (en) 1986-01-08
NO148887C (en) 1984-01-04
NO148887B (en) 1983-09-26
SU637087A3 (en) 1978-12-05
FR2351985B1 (en) 1980-06-27
US4054738A (en) 1977-10-18
FI66008C (en) 1984-08-10
IL50977A0 (en) 1977-01-31
AU2001376A (en) 1978-06-01
RO69709A (en) 1980-04-15
SE424730B (en) 1982-08-09
PT65955A (en) 1977-01-01
ATA948976A (en) 1978-07-15
AR213300A1 (en) 1979-01-15
GB1565854A (en) 1980-04-23
FR2361898A1 (en) 1978-03-17
RO75964A (en) 1981-02-28
DK153156C (en) 1989-02-20
DD128727A5 (en) 1977-12-07
GR65891B (en) 1980-12-01
SE441096B (en) 1985-09-09

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