AT321301B - Verfahren zur Herstellung neuer Pyridinderivate sowie von deren Säureadditionssalzen - Google Patents

Verfahren zur Herstellung neuer Pyridinderivate sowie von deren Säureadditionssalzen

Info

Publication number
AT321301B
AT321301B AT969471A AT969471A AT321301B AT 321301 B AT321301 B AT 321301B AT 969471 A AT969471 A AT 969471A AT 969471 A AT969471 A AT 969471A AT 321301 B AT321301 B AT 321301B
Authority
AT
Austria
Prior art keywords
production
acid addition
addition salts
pyridine derivatives
new pyridine
Prior art date
Application number
AT969471A
Other languages
German (de)
English (en)
Original Assignee
Manuf Prod Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manuf Prod Pharma filed Critical Manuf Prod Pharma
Application granted granted Critical
Publication of AT321301B publication Critical patent/AT321301B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT969471A 1970-11-11 1971-11-10 Verfahren zur Herstellung neuer Pyridinderivate sowie von deren Säureadditionssalzen AT321301B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5367570A GB1368948A (en) 1970-11-11 1970-11-11 Pyridine derivatives

Publications (1)

Publication Number Publication Date
AT321301B true AT321301B (de) 1975-03-25

Family

ID=10468621

Family Applications (2)

Application Number Title Priority Date Filing Date
AT969471A AT321301B (de) 1970-11-11 1971-11-10 Verfahren zur Herstellung neuer Pyridinderivate sowie von deren Säureadditionssalzen
AT151374*1A AT324341B (de) 1970-11-11 1971-11-10 Verfahren zur herstellung von neuen pyridinderivaten sowie deren saureadditionssalzen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT151374*1A AT324341B (de) 1970-11-11 1971-11-10 Verfahren zur herstellung von neuen pyridinderivaten sowie deren saureadditionssalzen

Country Status (11)

Country Link
US (2) US3819639A (en:Method)
JP (1) JPS51125083A (en:Method)
AT (2) AT321301B (en:Method)
BE (1) BE775166A (en:Method)
CA (1) CA1008859A (en:Method)
DE (1) DE2155483A1 (en:Method)
ES (1) ES424378A1 (en:Method)
FR (1) FR2113927B1 (en:Method)
GB (1) GB1368948A (en:Method)
LU (1) LU64237A1 (en:Method)
NL (1) NL7115510A (en:Method)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1368948A (en) * 1970-11-11 1974-10-02 Manuf Prod Pharma Pyridine derivatives
US3904636A (en) * 1971-11-09 1975-09-09 Christiaens Sa A 3-sulfonamido-4-phenyl aminopyridines and derivatives
GB1414793A (en) * 1972-07-28 1975-11-19 Manuf Prod Pharma Derivatives of phenylaminopyridine
US3920641A (en) * 1973-11-05 1975-11-18 Dow Chemical Co 1H-pyrido(2,3-c or 4,3-c) (1,2,6)thiadiazin-4(3H)-one-2,2-dioxides
GB1477664A (en) * 1974-04-17 1977-06-22 Christiaens Sa A Pyridine derivatives
US4055650A (en) * 1974-04-17 1977-10-25 A. Christiaens Societe Anonyme Certain 4-phenoxy(or phenylthio)-3-n-acylated-sulfonamido-pyridines
US4042693A (en) * 1975-04-14 1977-08-16 A. Christiaens Societe Anonyme Derivatives of 1,2,4-thiadiazine
US4128553A (en) * 1976-04-13 1978-12-05 The Dow Chemical Company Substituted pyridine thiocarbonyl halides and derivatives
US4078063A (en) * 1976-09-24 1978-03-07 Merck & Co., Inc. Piperazinylpyridines
US4129734A (en) * 1976-12-03 1978-12-12 The Dow Chemical Company Substituted pyridine carbonyl halides and derivatives
US4129733A (en) * 1976-12-06 1978-12-12 The Dow Chemical Company Substituted pyridine thionocarbonyl halides and derivatives
US4128551A (en) * 1976-12-06 1978-12-05 The Dow Chemical Co. Substituted pyridine carboxyl halides and derivatives
GB1593609A (en) * 1978-01-31 1981-07-22 Christiaens Sa A Pyridine sulfonamides
DE3117434A1 (de) * 1981-05-02 1982-11-18 Wolfram Dipl.-Ing. 7031 Magstadt Fischer Kompakt-regallager
EP0308371A1 (de) * 1987-09-18 1989-03-22 Ciba-Geigy Ag 4-Azasaccharine, 4-Aza-dihydro-oder-tetrahydrosaccharine und Verfahren zu deren Herstellung
JP2719600B2 (ja) * 1988-01-04 1998-02-25 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー シアノジエン類、ハロピリジン類、中間体及びそれらの製造方法
JP2664238B2 (ja) * 1989-03-01 1997-10-15 日清製粉株式会社 ニコチン酸またはそのエステル誘導体
FR2703051B1 (fr) * 1993-03-26 1995-04-28 Adir Nouvelles pyridothiadiazines, leurs procédés de préparation, et les compositions pharmaceutiques qui les contiennent.
ES2206604T3 (es) * 1995-11-15 2004-05-16 Yamanouchi Pharmaceutical Co., Ltd. Inhibidores de la neurotoxicidad del acido kainico y derivados de la piridotiazina.
US6225310B1 (en) 1996-01-17 2001-05-01 Novo Nordisk A/S Fused 1,2,4-thiadiazine derivatives, their preparation and use
KR19990077319A (ko) * 1996-01-17 1999-10-25 한센 핀 베네드, 안네 제헤르 축합된 1,2,4-티아디아진 및 축합된 1,4-티아진 유도체, 그것의제조방법 및 사용
BR9707004A (pt) * 1996-01-17 1999-07-20 Novo Nordisk As Composto processo para preparar o mesmo composição farmacêutica utilização do composto e processos para tratamento de doenças do sistema endocinológico e para a manufatura de um medicamento
EP1000066A1 (en) * 1997-07-16 2000-05-17 Novo Nordisk A/S Fused 1,2,4-thiadiazine derivatives, their preparation and use
US6022884A (en) 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
SK14802002A3 (sk) 2000-03-20 2003-05-02 Teva Pharmaceutical Industries Ltd. Nový spôsob prípravy medziproduktu torsemidu
WO2002000665A1 (en) * 2000-06-26 2002-01-03 Novo Nordisk A/S Use of potassium channel openers for the treatment of insulitis
MXPA03010269A (es) 2001-05-11 2004-05-05 Vertex Pharma Derivados de 2,5-disubstituida piridina, pirimidina, piridazina y 1,2,4-triazina para usarse como inhibidores de p38.
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
JP2003081937A (ja) * 2001-09-07 2003-03-19 Bayer Ag ベンゼンスルホンアミド誘導体
PL1608374T3 (pl) 2003-03-24 2009-08-31 Axikin Pharmaceuticals Inc 2-Fenoksy i 2-fenylosulfonoamidowe pochodne o aktywności antagonistycznej w stosunku do CCR3 do leczenia astmy i innych zaburzeń o podłożu zapalnym lub immunologicznym
CN101287411B (zh) 2005-04-28 2013-03-06 普罗秋斯生物医学公司 药物信息系统及其用途
US7625896B2 (en) * 2005-11-25 2009-12-01 Hoffman-La Roche Inc. Pyridylsulfonamide derivatives
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白（rap）-缀合物对肝病症的治疗
ES2728225T3 (es) 2009-02-20 2019-10-23 2 Bbb Medicines B V Sistema de administración de fármacos a base de glutatión
KR101909711B1 (ko) 2009-05-06 2018-12-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
CN102892754A (zh) * 2010-03-17 2013-01-23 埃克希金医药品有限公司 芳基磺酰胺ccr3拮抗剂
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674794A (en) * 1970-03-18 1972-07-04 Ciba Geigy Corp Certain-3-pyridine-sulfonamide derivatives
GB1368948A (en) * 1970-11-11 1974-10-02 Manuf Prod Pharma Pyridine derivatives
US3904636A (en) * 1971-11-09 1975-09-09 Christiaens Sa A 3-sulfonamido-4-phenyl aminopyridines and derivatives

Also Published As

Publication number Publication date
GB1368948A (en) 1974-10-02
CA1008859A (en) 1977-04-19
LU64237A1 (en:Method) 1972-05-29
DE2155483A1 (de) 1972-06-08
NL7115510A (en:Method) 1972-05-15
ES424378A1 (es) 1976-07-01
FR2113927B1 (en:Method) 1975-10-10
JPS51125083A (en) 1976-11-01
BE775166A (en:Method) 1972-05-10
AT324341B (de) 1975-08-25
US3819639A (en) 1974-06-25
FR2113927A1 (en:Method) 1972-06-30
US3991057A (en) 1976-11-09

Similar Documents

Publication Publication Date Title
AT321301B (de) Verfahren zur Herstellung neuer Pyridinderivate sowie von deren Säureadditionssalzen
AT321477B (de) Verfahren zur Herstellung von neuen O-Acyllysergolen sowie deren Salzen
AT305284B (de) Verfahren zur Herstellung neuer heterocyclischer Äther sowie deren Säureadditionssalzen
AT297701B (de) Verfahren zur Herstellung neuer Bistriazolyl-bisphenyl-methanen und deren Salze
AT315858B (de) Verfahren zur Herstellung von neuen Triazolobenzodiazepinderivaten sowie von deren Salzen
AT312580B (de) Verfahren zur Herstellung neuer p-Aminophenylamidine und deren Säureadditionssalze
AT313267B (de) Verfahren zur Herstellung neuer Nitrofuranderivate und deren Salze
AT325597B (de) Verfahren zur herstellung von neuen benzobicycloalkanaminen und deren säureadditionssalzen
AT302301B (de) Verfahren zur Herstellung von neuen Pyridinderivaten, von deren Metallkomplexverbindungen sowie von Säureadditionssalzen von den Estern
AT318572B (de) Verfahren zur Herstellung neuer 1-Phenoxy-2-hydroxy-3-hydroxyalkylaminopropane sowie deren Säureadditionssalze
AT307419B (de) Verfahren zur Herstellung von neuen Benzodioxanderivaten sowie von deren Salzen
AT306258B (de) Verfahren zur Herstellung neuer Tropan-3-ol-Derivate und deren Salze
AT313872B (de) Verfahren zur Herstellung neuer substituierter 10-Aminoalkyl-10-11-dihydro-5,10-methano-5H-dibenzo[a,d]-cycloheptene sowie deren Säureadditionssalze
AT307431B (de) Verfahren zur Herstellung neuer Sulfamoylpyrimidine sowie deren Salze
AT310762B (de) Verfahren zur Herstellung von neuen Triazolbenzodiazepin-Derivaten sowie von deren Salzen
AT302304B (de) Verfahren zur Herstellung neuer Piperazinverbindungen sowie von deren Salzen
AT303734B (de) Verfahren zur Herstellung von neuen N-Vinylchinolonen sowie deren Salzen
ATA237274A (de) Verfahren zur herstellung neuer indenopyridinderivate sowie von deren saureadditionssalzen
AT330147B (de) Verfahren zur herstellung von 2-methoxy-5-alkylsulfonylbenzamiden sowie deren saureadditionssalzen
AT313902B (de) Verfahren zur Herstellung von Piperazinderivaten sowie von deren Säureadditionssalzen
AT321306B (de) Verfahren zur Herstellung von neuen 1-Vinylcarbonyl-piperazin-Derivaten sowie von deren Säureadditionssalzen
AT308759B (de) Verfahren zur Herstellung von neuen Benzodiazepinderivaten sowie von deren Salzen
AT311368B (de) Verfahren zur Herstellung von neuen Sulfonylaminopyrimidinen sowie deren Salzen
AT322571B (de) Verfahren zur herstellung von neuen basisch substituierten thiolcarbamidsaeure-alkylestern sowie von deren saeureadditionssalzen und quartaeren ammoniumsalzen
AT330775B (de) Verfahren zur herstellung von phenoxyessigsaure-derivaten sowie deren salzen

Legal Events

Date Code Title Description
EIH Change in the person of patent owner
ELJ Ceased due to non-payment of the annual fee