AT299960B - Process for the preparation of new benzodiazepine derivatives - Google Patents

Process for the preparation of new benzodiazepine derivatives

Info

Publication number
AT299960B
AT299960B AT167371A AT167371A AT299960B AT 299960 B AT299960 B AT 299960B AT 167371 A AT167371 A AT 167371A AT 167371 A AT167371 A AT 167371A AT 299960 B AT299960 B AT 299960B
Authority
AT
Austria
Prior art keywords
preparation
benzodiazepine derivatives
new benzodiazepine
new
derivatives
Prior art date
Application number
AT167371A
Other languages
German (de)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of AT299960B publication Critical patent/AT299960B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06P—DYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
    • D06P1/00—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed
    • D06P1/44—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed using insoluble pigments or auxiliary substances, e.g. binders
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06P—DYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
    • D06P3/00—Special processes of dyeing or printing textiles, or dyeing leather, furs, or solid macromolecular substances in any form, classified according to the material treated
    • D06P3/80—Inorganic fibres
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06P—DYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
    • D06P3/00—Special processes of dyeing or printing textiles, or dyeing leather, furs, or solid macromolecular substances in any form, classified according to the material treated
    • D06P3/82—Textiles which contain different kinds of fibres
    • D06P3/854—Textiles which contain different kinds of fibres containing modified or unmodified fibres, i.e. containing the same type of fibres having different characteristics, e.g. twisted and not-twisted fibres

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Textile Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT167371A 1968-06-12 1969-06-11 Process for the preparation of new benzodiazepine derivatives AT299960B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73625068A 1968-06-12 1968-06-12
US80346169A 1969-02-28 1969-02-28

Publications (1)

Publication Number Publication Date
AT299960B true AT299960B (en) 1972-07-10

Family

ID=27113017

Family Applications (2)

Application Number Title Priority Date Filing Date
AT554069A AT289125B (en) 1968-06-12 1969-06-11 Process for the preparation of benzodiazepine derivatives
AT167371A AT299960B (en) 1968-06-12 1969-06-11 Process for the preparation of new benzodiazepine derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT554069A AT289125B (en) 1968-06-12 1969-06-11 Process for the preparation of benzodiazepine derivatives

Country Status (12)

Country Link
US (1) US3546212A (en)
AT (2) AT289125B (en)
BE (1) BE734376A (en)
CA (1) CA950453A (en)
CH (3) CH523267A (en)
DE (1) DE1929910A1 (en)
ES (1) ES368239A1 (en)
FR (1) FR2010744A1 (en)
GB (1) GB1239380A (en)
IE (1) IE33286B1 (en)
NL (3) NL143927B (en)
SE (1) SE347510B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723414A (en) * 1970-02-13 1973-03-27 Schering Corp 1-polyfluoroalkyl benzodiazepines
US3896109A (en) * 1971-09-30 1975-07-22 Upjohn Co 2,3-dehydro-1h-1,4-benzodiazepines
US4083948A (en) * 1977-04-04 1978-04-11 Hoffmann-La Roche, Inc. Benzodiazepine radioimmunoassay using I125-label
SE7900456L (en) * 1978-05-31 1979-07-20 Ferrosan As BENSODIAZEPTINE CONCENTRATION DETERMINATION
DE3124013A1 (en) * 1981-06-19 1982-12-30 Kali-Chemie Pharma Gmbh, 3000 Hannover 2-ACYLAMINOMETHYL-1,4-BENZODIAZEPINE COMPOUNDS, METHODS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3621551C1 (en) * 1986-06-27 1987-07-02 Eckard 5810 Witten De Feller Cutting tool for lathe - has carrier arm and screw cooperating to retain lower packer plate and upper cutting insert in tool
DE3836538A1 (en) * 1988-10-27 1990-05-03 Christian Rinke Packaging container, in particular bottle
GB8917222D0 (en) * 1989-07-27 1989-09-13 Schering Agrochemicals Ltd Herbicides
BR9307264A (en) * 1992-10-16 1999-05-11 Nippon Soda Co Pyrimidine derivatives herbicide and fungicide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones

Also Published As

Publication number Publication date
US3546212A (en) 1970-12-08
DE1929910A1 (en) 1970-01-02
IE33286L (en) 1969-12-12
CH523898A (en) 1972-06-15
SE347510B (en) 1972-08-07
GB1239380A (en) 1971-07-14
BE734376A (en) 1969-12-11
NL143927B (en) 1974-11-15
NL6908966A (en) 1969-12-16
CH550185A (en) 1974-06-14
NL6908866A (en) 1969-12-22
FR2010744A1 (en) 1970-02-20
CH523267A (en) 1972-05-31
ES368239A1 (en) 1971-06-16
AT289125B (en) 1971-04-13
CA950453A (en) 1974-07-02
IE33286B1 (en) 1974-05-15
NL6908658A (en) 1969-12-16

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee