AT294075B - Process for the preparation of new 2- (5-nitro-2-imidazolyl) -benzimidazoles and their salts - Google Patents

Process for the preparation of new 2- (5-nitro-2-imidazolyl) -benzimidazoles and their salts

Info

Publication number
AT294075B
AT294075B AT351470A AT351470A AT294075B AT 294075 B AT294075 B AT 294075B AT 351470 A AT351470 A AT 351470A AT 351470 A AT351470 A AT 351470A AT 294075 B AT294075 B AT 294075B
Authority
AT
Austria
Prior art keywords
benzimidazoles
imidazolyl
nitro
salts
preparation
Prior art date
Application number
AT351470A
Other languages
German (de)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of AT294075B publication Critical patent/AT294075B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/95—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by nitrogen atoms, attached to other ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
    • C07C209/325—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups reduction by other means than indicated in C07C209/34 or C07C209/36
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
    • C07C209/36—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to carbon atoms of six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT351470A 1969-04-19 1970-04-17 Process for the preparation of new 2- (5-nitro-2-imidazolyl) -benzimidazoles and their salts AT294075B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1920635A DE1920635C3 (en) 1969-04-19 1969-04-19 2- (1-methyl-5-nitro-2-imidazolyl) benzimidazoles

Publications (1)

Publication Number Publication Date
AT294075B true AT294075B (en) 1971-11-10

Family

ID=5732064

Family Applications (1)

Application Number Title Priority Date Filing Date
AT351470A AT294075B (en) 1969-04-19 1970-04-17 Process for the preparation of new 2- (5-nitro-2-imidazolyl) -benzimidazoles and their salts

Country Status (15)

Country Link
JP (1) JPS4914231B1 (en)
AT (1) AT294075B (en)
BE (1) BE749102A (en)
CH (2) CH546774A (en)
CS (1) CS167896B2 (en)
DE (1) DE1920635C3 (en)
DK (1) DK137758B (en)
ES (1) ES378368A1 (en)
FI (1) FI52861C (en)
FR (1) FR2042351B1 (en)
GB (1) GB1312056A (en)
NL (1) NL7005703A (en)
NO (1) NO126624B (en)
SE (1) SE364962B (en)
ZA (1) ZA702577B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053472A (en) * 1969-04-19 1977-10-11 Schering Aktiengesellschaft 2-(5-nitro-2-imidazolyl)-benzimidazoles
IT1043840B (en) * 1971-05-08 1980-02-29 Poli Ind Chimica Spa PYRIMIDINES 2 5 REPLACED AND PROCESS FOR THEIR PREPARATION
US3996238A (en) * 1972-02-08 1976-12-07 Ciba-Geigy Corporation 4- or 5-Nitroimidazoles and processes for their manufacture
BE795636A (en) * 1972-02-19 1973-08-20 Schering Ag NITROIMIDAZOLYLPYRIMIDINES, AND THEIR PREPARATION PROCESS
PT78358B (en) * 1983-04-07 1986-05-30 Smith Kline French Lab Chemical process
DE69525418T2 (en) * 1994-05-31 2002-10-17 Mitsui Chemicals Inc Benzimidazole derivatives
EP0777656B1 (en) * 1994-08-26 2004-04-14 Auckland Division Cancer Society Of New Zealand (Incorporated) Novel dna-targeted alkylating agents

Also Published As

Publication number Publication date
GB1312056A (en) 1973-04-04
CH546774A (en) 1974-03-15
BE749102A (en) 1970-10-19
FR2042351A1 (en) 1971-02-12
DE1920635B2 (en) 1978-11-02
CH546768A (en) 1974-03-15
FI52861C (en) 1977-12-12
DE1920635C3 (en) 1979-06-28
ES378368A1 (en) 1972-06-16
CS167896B2 (en) 1976-05-28
NO126624B (en) 1973-03-05
FR2042351B1 (en) 1973-07-13
NL7005703A (en) 1970-10-21
SE364962B (en) 1974-03-11
FI52861B (en) 1977-08-31
ZA702577B (en) 1971-01-27
DK137758B (en) 1978-05-01
DE1920635A1 (en) 1970-10-29
JPS4914231B1 (en) 1974-04-05
DK137758C (en) 1978-10-09

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