AT240539B - Verfahren zur Herstellung von 5,6-Dichlor-3,17α-dihydroxy-16β-methyl-allopregnan-20-on bzw. von dessen 3-Acylaten - Google Patents

Verfahren zur Herstellung von 5,6-Dichlor-3,17α-dihydroxy-16β-methyl-allopregnan-20-on bzw. von dessen 3-Acylaten

Info

Publication number
AT240539B
AT240539B AT702759A AT702759A AT240539B AT 240539 B AT240539 B AT 240539B AT 702759 A AT702759 A AT 702759A AT 702759 A AT702759 A AT 702759A AT 240539 B AT240539 B AT 240539B
Authority
AT
Austria
Prior art keywords
allopregnan
acylates
dihydroxy
dichloro
methyl
Prior art date
Application number
AT702759A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of AT240539B publication Critical patent/AT240539B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT702759A 1958-10-01 1959-09-28 Verfahren zur Herstellung von 5,6-Dichlor-3,17α-dihydroxy-16β-methyl-allopregnan-20-on bzw. von dessen 3-Acylaten AT240539B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76452458A 1958-10-01 1958-10-01

Publications (1)

Publication Number Publication Date
AT240539B true AT240539B (de) 1965-06-10

Family

ID=25070958

Family Applications (1)

Application Number Title Priority Date Filing Date
AT702759A AT240539B (de) 1958-10-01 1959-09-28 Verfahren zur Herstellung von 5,6-Dichlor-3,17α-dihydroxy-16β-methyl-allopregnan-20-on bzw. von dessen 3-Acylaten

Country Status (6)

Country Link
US (1) US3547913A (de)
AT (1) AT240539B (de)
BE (1) BE583145A (de)
CH (1) CH389597A (de)
ES (1) ES252585A1 (de)
GB (2) GB923624A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3676433A (en) * 1970-09-15 1972-07-11 Upjohn Co Improved process for the 5{60 ,6{60 -epoxidation of {66 {11 -double bonds

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2588391A (en) * 1947-05-22 1952-03-11 Glidden Co 16-alkyl steroids and process of preparing
US2705233A (en) * 1950-05-29 1955-03-29 Glidden Co 16, 17-oxido-pregnane-3alpha-ol-3, 20-dione
US2752339A (en) * 1950-09-09 1956-06-26 Glidden Co Preparation of cortisone
US2805230A (en) * 1952-08-02 1957-09-03 Syntex Sa Esters of 17alpha-hydroxy progesterone
US2750381A (en) * 1952-08-21 1956-06-12 Upjohn Co Steroid alkali-metal enolates
US2884417A (en) * 1952-12-17 1959-04-28 Merck & Co Inc 5, 6-dichloro pregnanes
US2789989A (en) * 1953-05-13 1957-04-23 Glidden Co Preparation of 21-halo steroids
US2897219A (en) * 1953-06-12 1959-07-28 Ciba Pharm Prod Inc delta5-20-keto-3:16:21-trihydroxy-pregnenes and esters thereof
US2697109A (en) * 1953-06-19 1954-12-14 Searle & Co 16-nitromethylpregnen-20-ones and process
US2874154A (en) * 1954-10-15 1959-02-17 Syntex Sa Process for the production of 20-keto-21-iodo steroids
US2822381A (en) * 1954-11-24 1958-02-04 Searle & Co 3-oxygenated 16-hydroxy-d-homopregnen-20-ones and their esters
US2811522A (en) * 1955-02-10 1957-10-29 Merck & Co Inc Preparation of 5, 6-dichloro-pregnane-3, 17-diol-20-one from esters of 5, 6-dichloro-16-pregnene-3-ol-20-one

Also Published As

Publication number Publication date
BE583145A (fr) 1960-03-30
ES252585A1 (es) 1960-03-01
GB923623A (en) 1963-04-18
US3547913A (en) 1970-12-15
GB923624A (en) 1963-04-18
CH389597A (de) 1965-03-31

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