AR242590A1 - Glycoprotein modified by oxidation and reduction, inhibiting the ribosomes, method for its production and immunotoxins contaning said glycoprotein - Google Patents
Glycoprotein modified by oxidation and reduction, inhibiting the ribosomes, method for its production and immunotoxins contaning said glycoproteinInfo
- Publication number
- AR242590A1 AR242590A1 AR86306244A AR30624486A AR242590A1 AR 242590 A1 AR242590 A1 AR 242590A1 AR 86306244 A AR86306244 A AR 86306244A AR 30624486 A AR30624486 A AR 30624486A AR 242590 A1 AR242590 A1 AR 242590A1
- Authority
- AR
- Argentina
- Prior art keywords
- glycoprotein
- contaning
- immunotoxins
- ribosomes
- inhibiting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
- A61K47/6819—Plant toxins
- A61K47/6825—Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
- A61K47/6819—Plant toxins
- A61K47/6825—Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
- A61K47/6827—Ricin A
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8518982A FR2591895B1 (en) | 1985-12-20 | 1985-12-20 | LONG-LASTING IN VIVO IMMUNOTOXINS HAVING MODIFIED RICIN A CHAIN ON ITS POLYSACCHARIDE PATTERNS |
Publications (1)
Publication Number | Publication Date |
---|---|
AR242590A1 true AR242590A1 (en) | 1993-04-30 |
Family
ID=9326039
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR86306244A AR242590A1 (en) | 1985-12-20 | 1986-12-19 | Glycoprotein modified by oxidation and reduction, inhibiting the ribosomes, method for its production and immunotoxins contaning said glycoprotein |
Country Status (3)
Country | Link |
---|---|
AR (1) | AR242590A1 (en) |
FR (1) | FR2591895B1 (en) |
ZA (1) | ZA869573B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ218460A (en) * | 1985-11-29 | 1989-07-27 | Univ Melbourne | Ricin-antibody conjugate |
DE4106389A1 (en) * | 1991-02-28 | 1992-09-03 | Behringwerke Ag | FUSION PROTEINS FOR PRODRUG ACTIVATION, THEIR PRODUCTION AND USE |
US6610299B1 (en) | 1989-10-19 | 2003-08-26 | Aventis Pharma Deutschland Gmbh | Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates |
US6475486B1 (en) | 1990-10-18 | 2002-11-05 | Aventis Pharma Deutschland Gmbh | Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates |
US7241595B2 (en) | 1989-10-20 | 2007-07-10 | Sanofi-Aventis Pharma Deutschland Gmbh | Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL47372A (en) * | 1975-05-27 | 1979-10-31 | Yeda Res & Dev | Fab'dimers bound to daunomycin or adriamycin,their preparation and pharmaceutical compositions containing same |
JPS5843926A (en) * | 1981-09-08 | 1983-03-14 | Suntory Ltd | Selective carcinostatic agent |
CA1203164A (en) * | 1982-03-09 | 1986-04-15 | Thomas J. Mckearn | Antibody conjugates |
-
1985
- 1985-12-20 FR FR8518982A patent/FR2591895B1/en not_active Expired
-
1986
- 1986-12-19 AR AR86306244A patent/AR242590A1/en active
- 1986-12-19 ZA ZA869573A patent/ZA869573B/en unknown
Also Published As
Publication number | Publication date |
---|---|
FR2591895B1 (en) | 1988-08-26 |
ZA869573B (en) | 1987-08-26 |
FR2591895A1 (en) | 1987-06-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR242186A1 (en) | Process for the production of 2,2,6,6,-tetraalkyl 4 piperidylamines | |
DE3664489D1 (en) | Wear-resistant, sintered iron alloy and process for producing the same | |
AR242590A1 (en) | Glycoprotein modified by oxidation and reduction, inhibiting the ribosomes, method for its production and immunotoxins contaning said glycoprotein | |
GB8620236D0 (en) | Inert gas production | |
CS326686A2 (en) | Zasobnik pro tycovite predmety, zejmena cigarety | |
GB2185493B (en) | Metal production | |
DE3375978D1 (en) | Shaped iron catalytic compound, its production and its use | |
GR3001236T3 (en) | Glycoproteins modified by oxidation followed by reduction, which inhibit ribosomes, production process and immunotoxines containing such a glycoprotein | |
EP0172697A3 (en) | Octahydro-oxazoloû4,5-g¨quinolines | |
OA08376A (en) | 3,7-disubstituted-3-cephem compounds and processes for production of the same. | |
EP0216585A3 (en) | 2,6,7-trisubstituted-3-methylenebicyclo û3.3.0¨octanes and process for production thereof | |
GB2184108B (en) | Gallium production | |
GB8428332D0 (en) | Mineshaft closures | |
IE852757L (en) | Diastereoselective reduction process. | |
HUT40634A (en) | Process for producing 4-hydroxy-benzisothiazol-3/2h/-one-1,1-dioxide | |
GB8717488D0 (en) | Steel production | |
PL251271A1 (en) | Multi-stage cyclohexane oxidation method | |
CS782785A1 (en) | Dekontaminacni vana, zejmena pro dekontamimaci pohonu regulacnich organu jaderneho reaktoru | |
CS80185A1 (en) | Polyuretanovy valcek, najmae pre tepovace kobercovpolyuretanovy valcek,najma pre tepovace kobercov | |
CS964485A1 (en) | Zpusob snizovani fluktuace tlaku vzduchu v okoli rotujiciho telesa, napr. drevoobrabeciho nastroje | |
CS1045584A1 (en) | Hmoty,zejmena pro lite bezesve podlahy | |
GB8410030D0 (en) | Poly-1-substituted-cyclohexa-1,3-dienes | |
GB8404495D0 (en) | Purifying transition metals | |
CS393486A1 (en) | Zariadenie pre privod tlakovej kvapaliny do pracovnej komory trecieho uzaveru diferencialu, hlavne pre polnohospodarske traktory | |
CS747985A1 (en) | Zarizeni k plneni zasobniku prirezy, zejmena trubek pro vyrobu chladicu |