AR211548A1 - Metodo de preparacion de nuevos derivados de alfa-fenil-2-hidroxibencilidenicos de aminoacidos,sus sales alcalinas y sus amidas - Google Patents

Metodo de preparacion de nuevos derivados de alfa-fenil-2-hidroxibencilidenicos de aminoacidos,sus sales alcalinas y sus amidas

Info

Publication number
AR211548A1
AR211548A1 AR264109A AR26410976A AR211548A1 AR 211548 A1 AR211548 A1 AR 211548A1 AR 264109 A AR264109 A AR 264109A AR 26410976 A AR26410976 A AR 26410976A AR 211548 A1 AR211548 A1 AR 211548A1
Authority
AR
Argentina
Prior art keywords
hydroxybenzylidenic
fenyl
amides
derivatives
amino acids
Prior art date
Application number
AR264109A
Other languages
English (en)
Spanish (es)
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Application granted granted Critical
Publication of AR211548A1 publication Critical patent/AR211548A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/04Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/10Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • C07C251/16Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AR264109A 1975-08-01 1976-07-28 Metodo de preparacion de nuevos derivados de alfa-fenil-2-hidroxibencilidenicos de aminoacidos,sus sales alcalinas y sus amidas AR211548A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7524065A FR2319338A1 (fr) 1975-08-01 1975-08-01 Nouveaux derives de a- phenyl benzylideniques des acides amines, leur preparation et les medicaments qui en contiennent

Publications (1)

Publication Number Publication Date
AR211548A1 true AR211548A1 (es) 1978-01-30

Family

ID=9158650

Family Applications (1)

Application Number Title Priority Date Filing Date
AR264109A AR211548A1 (es) 1975-08-01 1976-07-28 Metodo de preparacion de nuevos derivados de alfa-fenil-2-hidroxibencilidenicos de aminoacidos,sus sales alcalinas y sus amidas

Country Status (24)

Country Link
US (2) US4094992A (US06650917-20031118-M00005.png)
JP (1) JPS5219644A (US06650917-20031118-M00005.png)
AR (1) AR211548A1 (US06650917-20031118-M00005.png)
AT (1) AT346312B (US06650917-20031118-M00005.png)
AU (1) AU496994B2 (US06650917-20031118-M00005.png)
BE (1) BE844737A (US06650917-20031118-M00005.png)
CA (1) CA1072112A (US06650917-20031118-M00005.png)
CH (1) CH616148A5 (US06650917-20031118-M00005.png)
DE (1) DE2634288A1 (US06650917-20031118-M00005.png)
DK (1) DK346276A (US06650917-20031118-M00005.png)
ES (1) ES450300A1 (US06650917-20031118-M00005.png)
FR (1) FR2319338A1 (US06650917-20031118-M00005.png)
GB (1) GB1506808A (US06650917-20031118-M00005.png)
GR (1) GR60854B (US06650917-20031118-M00005.png)
IE (1) IE43143B1 (US06650917-20031118-M00005.png)
IL (1) IL50019A (US06650917-20031118-M00005.png)
LU (1) LU75514A1 (US06650917-20031118-M00005.png)
MX (1) MX4018E (US06650917-20031118-M00005.png)
NL (1) NL170627C (US06650917-20031118-M00005.png)
NO (1) NO142172C (US06650917-20031118-M00005.png)
NZ (1) NZ181444A (US06650917-20031118-M00005.png)
PT (1) PT65426B (US06650917-20031118-M00005.png)
SE (1) SE429651B (US06650917-20031118-M00005.png)
ZA (1) ZA764096B (US06650917-20031118-M00005.png)

Families Citing this family (40)

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FR2516509B1 (fr) * 1981-11-18 1985-07-26 Synthelabo Derives benzylideniques, leur preparation et leur application en therapeutique
FR2484410A2 (fr) * 1979-02-12 1981-12-18 Synthelabo Derives benzylideniques et leur application en therapeutique
DE3124091C2 (de) 1981-06-19 1983-06-01 Degussa Ag, 6000 Frankfurt N-(3-Cyanopropanoyl)-aminocarbonsäureester und deren Verwendung
US4478958A (en) * 1981-07-10 1984-10-23 Kopper Company, Inc. Method for preparing phenolic foams using anhydrous aryl sulfonic acid catalysts
FR2535318B2 (fr) * 1981-11-18 1985-09-06 Synthelabo Derives benzylideniques, leur preparation et leur application en therapeutique
FR2535319B2 (fr) * 1981-11-18 1985-10-31 Synthelabo Derives methyles benzylideniques, leur preparation et leur application en therapeutique
FR2536070A1 (fr) * 1982-11-15 1984-05-18 Synthelabo Diphenyl-azomethines hydroxylees, leur preparation et leur application en therapeutique
FR2536746A1 (fr) * 1982-11-29 1984-06-01 Synthelabo Derives benzylideniques alkyles, leur preparation et leur application en therapeutique
FR2536747A1 (fr) * 1982-11-29 1984-06-01 Synthelabo Derives benzylideniques soufres, leur preparation et leur application en therapeutique
FR2544308B1 (fr) * 1983-04-14 1985-06-14 Synthelabo Ethines substituees, leur preparation et leur application en therapeutique
FR2544309B1 (fr) * 1983-04-14 1986-01-10 Synthelabo Diphenylazomethines hydroxylees, leur preparation et leur application en therapeutique
FR2545822B1 (fr) * 1983-05-11 1985-07-05 Synthelabo Diphenylazomethines portant une chaine esterifiee, leur preparation et leur application en therapeutique
FR2570696B1 (fr) * 1984-09-27 1986-11-21 Synthelabo Derives de diphenylazomethines a chaine insaturee, leur preparation et leur application en therapeutique
FR2577923B1 (fr) * 1985-02-26 1988-09-09 Synthelabo Diphenylazomethines carboxylees, leur preparation et leur application
FR2595695B1 (fr) * 1986-03-12 1988-12-02 Synthelabo Derives de n-(((hydroxy-2 phenyl) (phenyl) methylene) amino-2) ethyl) acetamide, leur preparation et leur application en therapeutique
US5321047A (en) * 1988-06-03 1994-06-14 John Wyeth & Brother, Limited Method and amines used therein
US5278191A (en) * 1988-08-31 1994-01-11 G. D. Searle & Co. Diphenylmethylaminoacetamide derivatives as anti-convulsants
FR2647445B1 (fr) * 1989-05-23 1991-08-30 Oreal Acides n-carboalkyloxy amino-11 undecanoiques et leurs esters, leurs procedes de preparation et leur utilisation en tant qu'agents epaississants
US5247121A (en) * 1989-05-23 1993-09-21 L'oreal Alkyl esters of n-carboalkyloxy amino-11-undecanoic acids, their processes of preparation and their use as thickening agents
US5210313A (en) * 1992-01-10 1993-05-11 Maxdem Incorporated Preparation of 2,5-dichlorobenzophenones
KR20030059290A (ko) * 2000-11-30 2003-07-07 화이자 프로덕츠 인코포레이티드 Gaba 작용제 및 소르비톨 데하이드로게나제 억제제의혼합물
AU2002215160A1 (en) 2000-11-30 2002-06-11 Pfizer Products Inc. Combination of gaba agonists and aldose reductase inhibitors
WO2004100992A2 (en) * 2003-05-16 2004-11-25 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with gaba modulators, anticonvulsants or benzodiazapines
WO2005019163A2 (en) * 2003-08-20 2005-03-03 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
EP2354120A1 (en) 2003-08-20 2011-08-10 XenoPort, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
DK1691811T3 (da) 2003-12-11 2014-10-20 Sunovion Pharmaceuticals Inc Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression
BRPI0507190A (pt) * 2004-01-29 2007-06-26 Pfizer Prod Inc combinação de moduladores do ácido gama-aminobutìrico e antagonistas de 5-ht1b receptores
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
CA2620333A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en) * 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
EP2021000A2 (en) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenesis by modulating angiotensin
CN101466390B (zh) * 2006-06-15 2014-03-12 优时比制药有限公司 用于治疗难治性癫痫持续状态的肽类化合物
AU2007292848A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
TW200908957A (en) * 2007-06-15 2009-03-01 Xenoport Inc Use of prodrugs of GABA analogs, antispasticity agents, and prodrugs of GABAB receptor agonists for treating spasticity
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
WO2011113904A1 (en) 2010-03-17 2011-09-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
US3966793A (en) * 1964-06-15 1976-06-29 Clin Midy Intermediates for preparing 1,4-benzodiazepine-2-ones having a carboxylic acid ester or amide group in the 3-position
US3429874A (en) * 1966-12-22 1969-02-25 Schering Corp 1-polyhalogenoalkyl-2-oxo-1,3-dihydro-2h-1,4-benzodiazepines
IL47712A0 (en) 1974-08-21 1975-10-15 Sparamedica Ag Salt of a penicillanic acid derivative,its preparation and pharmaceutical compositions containing it
AT348512B (de) * 1976-08-02 1979-02-26 Hoffmann La Roche Verfahren zur herstellung von isoindol- derivaten

Also Published As

Publication number Publication date
AU496994B2 (en) 1978-11-16
DK346276A (da) 1977-02-02
SE7608625L (sv) 1977-02-02
IL50019A0 (en) 1976-09-30
PT65426A (fr) 1976-08-01
DE2634288C3 (US06650917-20031118-M00005.png) 1980-03-13
NO142172C (no) 1980-07-09
LU75514A1 (US06650917-20031118-M00005.png) 1978-02-09
IE43143B1 (en) 1980-12-31
US4094992A (en) 1978-06-13
ES450300A1 (es) 1977-09-01
GB1506808A (en) 1978-04-12
NZ181444A (en) 1978-03-06
NL7607533A (nl) 1977-02-03
NO762658L (US06650917-20031118-M00005.png) 1977-02-02
BE844737A (fr) 1977-01-31
IE43143L (en) 1977-02-01
MX4018E (es) 1981-11-03
IL50019A (en) 1979-07-25
SE429651B (sv) 1983-09-19
CH616148A5 (US06650917-20031118-M00005.png) 1980-03-14
JPS5219644A (en) 1977-02-15
ATA556176A (de) 1978-03-15
GR60854B (en) 1978-08-31
FR2319338A1 (fr) 1977-02-25
AT346312B (de) 1978-11-10
FR2319338B1 (US06650917-20031118-M00005.png) 1982-08-06
US4400394A (en) 1983-08-23
AU1645076A (en) 1978-02-02
JPS5714664B2 (US06650917-20031118-M00005.png) 1982-03-25
DE2634288A1 (de) 1977-02-03
CA1072112A (en) 1980-02-19
DE2634288B2 (US06650917-20031118-M00005.png) 1979-06-28
NO142172B (no) 1980-03-31
ZA764096B (en) 1977-06-29
PT65426B (fr) 1978-02-08
NL170627C (nl) 1982-12-01

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