AR127219A1 - METHODS FOR PREPARING (S)-4-CHLORO-2-AMINOBUTYRIC ACID HYDROCHLORIDE AND (S)-4-CHLORO-2-AMINOBUTYRATE - Google Patents

METHODS FOR PREPARING (S)-4-CHLORO-2-AMINOBUTYRIC ACID HYDROCHLORIDE AND (S)-4-CHLORO-2-AMINOBUTYRATE

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Publication number
AR127219A1
AR127219A1 ARP220102664A ARP220102664A AR127219A1 AR 127219 A1 AR127219 A1 AR 127219A1 AR P220102664 A ARP220102664 A AR P220102664A AR P220102664 A ARP220102664 A AR P220102664A AR 127219 A1 AR127219 A1 AR 127219A1
Authority
AR
Argentina
Prior art keywords
chloro
preparing
aminobutyric acid
acid hydrochloride
aminobutyrate
Prior art date
Application number
ARP220102664A
Other languages
Spanish (es)
Inventor
Lei Zhou
Wei Zeng
Yongjiang Liu
Ke Cheng
Original Assignee
Lier Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lier Chemical Co Ltd filed Critical Lier Chemical Co Ltd
Publication of AR127219A1 publication Critical patent/AR127219A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/20—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups

Abstract

Se proporciona un método para preparar clorhidrato del ácido (S)-4-cloro-2-aminobutírico, que comprende la siguiente etapa: hacer reaccionar clorhidrato de la lactona de L-homoserina de la fórmula (1) con cloruro de hidrógeno mediante cloración con apertura del anillo para producir clorhidrato del ácido (S)-4-cloro-2-aminobutírico de la fórmula (2). También se proporciona un método para preparar (S)-4-cloro-2-aminobutirato.A method for preparing (S)-4-chloro-2-aminobutyric acid hydrochloride is provided, comprising the following step: reacting L-homoserine lactone hydrochloride of formula (1) with hydrogen chloride by chlorination with ring opening to produce (S)-4-chloro-2-aminobutyric acid hydrochloride of formula (2). A method for preparing (S)-4-chloro-2-aminobutyrate is also provided.

ARP220102664A 2021-09-30 2022-09-30 METHODS FOR PREPARING (S)-4-CHLORO-2-AMINOBUTYRIC ACID HYDROCHLORIDE AND (S)-4-CHLORO-2-AMINOBUTYRATE AR127219A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202111163747 2021-09-30

Publications (1)

Publication Number Publication Date
AR127219A1 true AR127219A1 (en) 2023-12-27

Family

ID=85780440

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP220102664A AR127219A1 (en) 2021-09-30 2022-09-30 METHODS FOR PREPARING (S)-4-CHLORO-2-AMINOBUTYRIC ACID HYDROCHLORIDE AND (S)-4-CHLORO-2-AMINOBUTYRATE

Country Status (3)

Country Link
CN (1) CN116171270A (en)
AR (1) AR127219A1 (en)
WO (1) WO2023051768A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115093339A (en) * 2022-07-20 2022-09-23 永农生物科学有限公司 Synthetic method of L-glufosinate-ammonium intermediate
CN116655484B (en) * 2023-06-05 2024-02-13 佳木斯黑龙农药有限公司 Preparation method of L-4-chloro-2-aminobutyric acid ester hydrochloride

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590292A (en) * 1985-06-10 1986-05-20 Ciba-Geigy Corporation Process for the manufacture of cyclopropylamine
TW353663B (en) * 1991-04-06 1999-03-01 Hoechst Ag Process for the preparation of phosphorus-containing L-amino acids, their derivatives and intermediates for this process
CN109265336B (en) * 2018-09-26 2021-05-07 大丰跃龙化学有限公司 Method for synthesizing gamma-chlorobutyric acid
CN109369432B (en) * 2018-11-02 2021-06-25 永农生物科学有限公司 Preparation method of (S) -4-chloro-2-aminobutyrate
CN110845347B (en) * 2019-11-21 2021-10-15 利尔化学股份有限公司 Preparation method of chloro-homoserine alkyl ester

Also Published As

Publication number Publication date
TW202321190A (en) 2023-06-01
CN116171270A (en) 2023-05-26
WO2023051768A1 (en) 2023-04-06

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