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Publication of AR125008A1publicationCriticalpatent/AR125008A1/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms
(AREA)
Abstract
Se describe aquí un compuesto de fórmula (1), como se define en las reivindicaciones, donde X es N o CH; Y es N, NR³ o CR³; para inhibir TYK2 y tratar una enfermedad asociada con la actividad indeseable de tyk-2 (enfermedades relacionadas con tyk-2), un método de uso de los compuestos aquí descritos para el tratamiento de enfermedad inflamatoria o autoinmunitaria, y una composición farmacéutica que comprende el mismo.Disclosed herein is a compound of formula (1), as defined in the claims, wherein X is N or CH; Y is N, NR³ or CR³; for inhibiting TYK2 and treating a disease associated with undesirable tyk-2 activity (tyk-2-related diseases), a method of using the compounds described herein for the treatment of inflammatory or autoimmune disease, and a pharmaceutical composition comprising the same.