AR124675A2 - 2,2-DIFLUOROPROPANAMIDE AND METHYL BARDOXOLONE DERIVATIVES, POLYMORPHIC FORMS AND METHODS OF USE - Google Patents
2,2-DIFLUOROPROPANAMIDE AND METHYL BARDOXOLONE DERIVATIVES, POLYMORPHIC FORMS AND METHODS OF USEInfo
- Publication number
- AR124675A2 AR124675A2 ARP220100100A ARP220100100A AR124675A2 AR 124675 A2 AR124675 A2 AR 124675A2 AR P220100100 A ARP220100100 A AR P220100100A AR P220100100 A ARP220100100 A AR P220100100A AR 124675 A2 AR124675 A2 AR 124675A2
- Authority
- AR
- Argentina
- Prior art keywords
- difluoropropanamide
- methods
- polymorphic forms
- derivatives
- compound
- Prior art date
Links
Abstract
La presente invención se relaciona en general con el compuesto: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-ciano-2,2,6a,6b,9,9,12a-heptametil-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahidropiren-4a-il)-2,2-difluoropropanamida, formas polimórficas del mismo, métodos para su preparación y uso, composiciones farmacéuticas del mismo y conjuntos de elementos y artículos para elaborarlo. Reivindicación 1: Un compuesto con la fórmula (1), o una sal farmacéuticamente aceptable del mismo. Reivindicación 44: Un método para tratar o prevenir una condición asociada con la inflamación o estrés oxidativo en un paciente que los necesita, caracterizado porque comprende la administrar a un paciente una cantidad terapéuticamente efectiva del compuesto de acuerdo con las Reivindicaciones 1 a 3, las formas polimórficas de las Reivindicaciones 4 a 24, o la composición farmacéutica de acuerdo con una de las Reivindicaciones 26 a 43.The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl- 10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropyren-4a-yl)-2 ,2-difluoropropanamide, polymorphic forms thereof, methods for its preparation and use, pharmaceutical compositions thereof, and sets of elements and articles for making it. Claim 1: A compound of formula (1), or a pharmaceutically acceptable salt thereof. Claim 44: A method for treating or preventing a condition associated with inflammation or oxidative stress in a patient in need thereof, characterized in that it comprises administering to a patient a therapeutically effective amount of the compound according to Claims 1 to 3, the forms polymorphs of Claims 4 to 24, or the pharmaceutical composition according to one of Claims 26 to 43.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261687669P | 2012-04-27 | 2012-04-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR124675A2 true AR124675A2 (en) | 2023-04-26 |
Family
ID=75394165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP220100100A AR124675A2 (en) | 2012-04-27 | 2022-01-18 | 2,2-DIFLUOROPROPANAMIDE AND METHYL BARDOXOLONE DERIVATIVES, POLYMORPHIC FORMS AND METHODS OF USE |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR124675A2 (en) |
HR (1) | HRP20210384T1 (en) |
-
2021
- 2021-03-04 HR HRP20210384TT patent/HRP20210384T1/en unknown
-
2022
- 2022-01-18 AR ARP220100100A patent/AR124675A2/en unknown
Also Published As
Publication number | Publication date |
---|---|
HRP20210384T1 (en) | 2021-04-16 |
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