AR124110A1 - COMPOUNDS, COMPOSITIONS AND METHODS - Google Patents
COMPOUNDS, COMPOSITIONS AND METHODSInfo
- Publication number
- AR124110A1 AR124110A1 ARP210103209A ARP210103209A AR124110A1 AR 124110 A1 AR124110 A1 AR 124110A1 AR P210103209 A ARP210103209 A AR P210103209A AR P210103209 A ARP210103209 A AR P210103209A AR 124110 A1 AR124110 A1 AR 124110A1
- Authority
- AR
- Argentina
- Prior art keywords
- methods
- stereoisomer
- stereoisomers
- prodrug
- mixture
- Prior art date
Links
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente divulgación se refiere en general a moduladores de molécula pequeña de la Familia de NLR que contienen Dominio de Pirina 3 (NLRP3), o una sal farmacéuticamente aceptable, análogo enriquecido isotópicamente, estereoisómero, mezcla de estereoisómeros o profármaco del mismo, métodos de elaboración e intermedios de los mismos, y métodos de uso de los mismos. Un compuesto de fórmula (1) o una sal farmacéuticamente aceptable, análogo enriquecido isotópicamente, estereoisómero, mezcla de estereoisómeros o profármaco del mismo, como se define en la reivindicación 1, en donde: X es O ó S; Y es O ó S; A¹, A², A³, y A⁴ son cada uno independientemente N, CH, o CR¹; siempre que al menos uno de A¹, A², A³, y A⁴ sea CR¹.The present disclosure relates generally to small molecule modulators of the NLR Family containing Pyrin Domain 3 (NLRP3), or a pharmaceutically acceptable salt, isotopically enriched analogue, stereoisomer, mixture of stereoisomers, or prodrug thereof, methods of manufacture and intermediates thereof, and methods of using the same. A compound of formula (1) or a pharmaceutically acceptable salt, isotopically enriched analogue, stereoisomer, mixture of stereoisomers or prodrug thereof, as defined in claim 1, wherein: X is O or S; Y is O or S; A¹, A², A³, and A⁴ are each independently N, CH, or CR¹; provided that at least one of A¹, A², A³, and A⁴ is CR¹.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063116727P | 2020-11-20 | 2020-11-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR124110A1 true AR124110A1 (en) | 2023-02-15 |
Family
ID=86317661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP210103209A AR124110A1 (en) | 2020-11-20 | 2021-11-19 | COMPOUNDS, COMPOSITIONS AND METHODS |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR124110A1 (en) |
-
2021
- 2021-11-19 AR ARP210103209A patent/AR124110A1/en unknown
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