AR124109A1 - KRAS G12D INHIBITORS - Google Patents
KRAS G12D INHIBITORSInfo
- Publication number
- AR124109A1 AR124109A1 ARP210103208A ARP210103208A AR124109A1 AR 124109 A1 AR124109 A1 AR 124109A1 AR P210103208 A ARP210103208 A AR P210103208A AR P210103208 A ARP210103208 A AR P210103208A AR 124109 A1 AR124109 A1 AR 124109A1
- Authority
- AR
- Argentina
- Prior art keywords
- inhibitors
- kras
- prodrug
- bond
- formula
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención se relaciona con inhibidores de KRAS G12D de la fórmula (1), como se define en la reivindicación 1, en particular en donde: Y está seleccionado de un enlace, O, NR⁵⁵, S, S=O, o S(=O)₂; m, n, p o q está independientemente seleccionado de 0, 1, 2, 3, 4, 5, 6, 7, 8, 9 ó 10; una composición que contiene los inhibidores, una prodroga de los mismos, un compuesto PROTAC de los mismos y el uso de los mismos.The invention relates to KRAS G12D inhibitors of formula (1), as defined in claim 1, in particular wherein: Y is selected from a bond, O, NR⁵⁵, S, S=O, or S(= O)₂; m, n, p, or q is independently selected from 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10; a composition containing the inhibitors, a prodrug thereof, a PROTAC compound thereof, and the use thereof.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2021091540 | 2021-04-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR124109A1 true AR124109A1 (en) | 2023-02-15 |
Family
ID=86317659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP210103208A AR124109A1 (en) | 2021-04-30 | 2021-11-19 | KRAS G12D INHIBITORS |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR124109A1 (en) |
-
2021
- 2021-11-19 AR ARP210103208A patent/AR124109A1/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |