AR123279A1 - ANTI-CEACAM5 ANTIBODIES AND CONJUGATES AND USES THEREOF - Google Patents

ANTI-CEACAM5 ANTIBODIES AND CONJUGATES AND USES THEREOF

Info

Publication number
AR123279A1
AR123279A1 ARP210102323A ARP210102323A AR123279A1 AR 123279 A1 AR123279 A1 AR 123279A1 AR P210102323 A ARP210102323 A AR P210102323A AR P210102323 A ARP210102323 A AR P210102323A AR 123279 A1 AR123279 A1 AR 123279A1
Authority
AR
Argentina
Prior art keywords
antibodies
immunoconjugates
provides
conjugates
pharmaceutical compositions
Prior art date
Application number
ARP210102323A
Other languages
Spanish (es)
Inventor
Jan Anderl
Sabine Raab-Westphal
Stefan Hecht
Carl Deutsch
Min Shan
Doreen Knning
Willem N Sloot
Felix Hart
Christian Schrter
Lars Toleikis
Nir Berger
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of AR123279A1 publication Critical patent/AR123279A1/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La invención proporciona anticuerpos que se unen a la proteína CEACAM5 humana, así como ácidos nucleicos aislados y células huésped que comprenden una secuencia que codifica dichos anticuerpos. La invención también proporciona inmunoconjugados que comprenden dichos anticuerpos unidos a un agente inhibidor del crecimiento y composiciones farmacéuticas que comprenden anticuerpos o inmunoconjugados de la invención. La invención también proporciona el uso de los anticuerpos, inmunoconjugados y composiciones farmacéuticas de la invención para el tratamiento del cáncer o con fines de diagnóstico.The invention provides antibodies that bind to the human CEACAM5 protein, as well as isolated nucleic acids and host cells comprising a sequence encoding such antibodies. The invention also provides immunoconjugates comprising said antibodies linked to a growth inhibitory agent and pharmaceutical compositions comprising antibodies or immunoconjugates of the invention. The invention also provides the use of the antibodies, immunoconjugates and pharmaceutical compositions of the invention for the treatment of cancer or for diagnostic purposes.

ARP210102323A 2020-09-04 2021-08-18 ANTI-CEACAM5 ANTIBODIES AND CONJUGATES AND USES THEREOF AR123279A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20194711 2020-09-04

Publications (1)

Publication Number Publication Date
AR123279A1 true AR123279A1 (en) 2022-11-16

Family

ID=72422079

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP210102323A AR123279A1 (en) 2020-09-04 2021-08-18 ANTI-CEACAM5 ANTIBODIES AND CONJUGATES AND USES THEREOF

Country Status (1)

Country Link
AR (1) AR123279A1 (en)

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