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Publication of AR122427A1publicationCriticalpatent/AR122427A1/en
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Abstract
Un copolímero a base de poliacrilamida reduce o evita la agregación de proteínas y péptidos en las formulaciones acuosas en las interfaces hidrofóbicas, de este modo aumenta la estabilidad térmica de proteínas y péptidos en la formulación. Los métodos y las composiciones que comprenden el copolímero y una proteína o el copolímero e insulina se pueden usar para tratar afecciones que incluyen diabetes.A polyacrylamide-based copolymer reduces or prevents aggregation of proteins and peptides in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of proteins and peptides in the formulation. The methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used to treat conditions including diabetes.
ARP210101041A2020-04-172021-04-19
POLYMERIC EXCIPIENTS FOR BIOPHARMACEUTICAL FORMULATIONS
AR122427A1
(en)