AR122125A1 - BINDING CONSTRUCTIONS TO MAGEB2 - Google Patents

BINDING CONSTRUCTIONS TO MAGEB2

Info

Publication number
AR122125A1
AR122125A1 ARP210101368A ARP210101368A AR122125A1 AR 122125 A1 AR122125 A1 AR 122125A1 AR P210101368 A ARP210101368 A AR P210101368A AR P210101368 A ARP210101368 A AR P210101368A AR 122125 A1 AR122125 A1 AR 122125A1
Authority
AR
Argentina
Prior art keywords
antibody construct
mageb2
polynucleotide
vector
furthermore
Prior art date
Application number
ARP210101368A
Other languages
Spanish (es)
Inventor
Ian Nevin Foltz
Weihsu Claire Chen
Lars Gaedtke
Susmuth Mukund
Tobias Raum
Heiko Schuster
Kristin Tarbell
Johannes Brozy
Derek Piper
Markus Muenz
Igor DANGELO
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of AR122125A1 publication Critical patent/AR122125A1/en

Links

Abstract

La presente invención se refiere a una construcción de anticuerpo que comprende un dominio que se une a un péptido de MAGEB2 que forma complejo con un HLA y, opcionalmente, otro dominio que se une a CD3. Además, la invención proporciona un polinucleótido que codifica la construcción de anticuerpo, un vector que comprende dicho polinucleótido y una célula huésped transformada o transfectada con dicho polinucleótido o vector. Además, la invención proporciona un proceso para producir la construcción de anticuerpo de la invención, un uso médico de dicha construcción de anticuerpo y un kit que comprende dicha construcción de anticuerpo.The present invention relates to an antibody construct comprising a MAGEB2 peptide-binding domain complexed with an HLA and, optionally, another CD3-binding domain. Furthermore, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide, and a host cell transformed or transfected with said polynucleotide or vector. Furthermore, the invention provides a process for producing the antibody construct of the invention, a medical use of said antibody construct, and a kit comprising said antibody construct.

ARP210101368A 2020-05-19 2021-05-19 BINDING CONSTRUCTIONS TO MAGEB2 AR122125A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202063027148P 2020-05-19 2020-05-19

Publications (1)

Publication Number Publication Date
AR122125A1 true AR122125A1 (en) 2022-08-17

Family

ID=83218661

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP210101368A AR122125A1 (en) 2020-05-19 2021-05-19 BINDING CONSTRUCTIONS TO MAGEB2

Country Status (1)

Country Link
AR (1) AR122125A1 (en)

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