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Application filed by Homology Medicines IncfiledCriticalHomology Medicines Inc
Publication of AR121770A1publicationCriticalpatent/AR121770A1/en
Medicines Containing Material From Animals Or Micro-Organisms
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Micro-Organisms Or Cultivation Processes Thereof
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Abstract
Se proporcionan composiciones de virus adenoasociados (AAV) que pueden restaurar la función del gen IDS en las células, y métodos para usar estas composiciones de AAV para tratar trastornos asociados con la reducción de la función del gen IDS (por ejemplo, síndrome de Hunter). También se proporcionan composiciones, sistemas y métodos para preparar las composiciones de AAV.Adeno-associated virus (AAV) compositions that can restore IDS gene function in cells, and methods of using these AAV compositions to treat disorders associated with reduced IDS gene function (eg, Hunter syndrome) are provided. . Compositions, systems, and methods for preparing the AAV compositions are also provided.
ARP210100900A2020-04-062021-04-06
COMPOSITIONS OF ADENO-ASSOCIATED VIRUSES FOR THE TRANSFER OF THE IDS GENE AND THEIR METHODS OF USE
AR121770A1
(en)
antibody, methods for neutralizing infectious ebov, preventing, treating or ameliorating at least one ebov infection symptom or decreasing the frequency or severity of at least one ebov infection symptom and for increasing the survival or likelihood of survival of an individual suffering from ebov infection or an individual exposed to ebov or at risk of ebov exposure or acquisition, pharmaceutical composition, isolated polynucleotide molecule, vector, and cell.