AR120626A1 - SALTS OF AN FGFR INHIBITOR - Google Patents

SALTS OF AN FGFR INHIBITOR

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Publication number
AR120626A1
AR120626A1 ARP190101178A ARP190101178A AR120626A1 AR 120626 A1 AR120626 A1 AR 120626A1 AR P190101178 A ARP190101178 A AR P190101178A AR P190101178 A ARP190101178 A AR P190101178A AR 120626 A1 AR120626 A1 AR 120626A1
Authority
AR
Argentina
Prior art keywords
salts
fgfr
fgfr inhibitor
pyrido
morpholin
Prior art date
Application number
ARP190101178A
Other languages
Spanish (es)
Inventor
Qun Li
Jiacheng Zhou
Zhongjiang Jia
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of AR120626A1 publication Critical patent/AR120626A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente hace referencia a formas de sal del inhibidor de receptores del factor de crecimiento de fibroblastos (FGFR) 3-(2,6-difluoro-3,5-dimetoxifenil)-1-etil-8-(morfolin-4-ilmetil)-1,3,4,7-tetrahidro-2H-pirrolo[3’,2’:5,6]pirido[4,3-d]pirimidin-2-ona, lo que incluye métodos para su preparación donde el compuesto es útil en el tratamiento de enfermedades mediadas por FGFR, tales como el cáncer. Reivindicación 1: Una sal que es una sal de ácido de 3-(2,6-difluoro-3,5-dimetoxifenil)-1-etil-8-(morfolin-4-ilmetil)-1,3,4,7-tetrahidro-2H-pirrolo[3’,2’:5,6]pirido[4,3-d]pirimidin-2-ona, que tiene la estructura de fórmula (1), o un hidrato o solvato de esta.This refers to salt forms of the fibroblast growth factor receptor (FGFR) inhibitor 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholin-4-ylmethyl) -1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one, including methods for its preparation where the compound is useful in the treatment of FGFR-mediated diseases, such as cancer. Claim 1: A salt which is a 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholin-4-ylmethyl)-1,3,4,7- tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one, having the structure of formula (1), or a hydrate or solvate thereof.

ARP190101178A 2018-05-04 2019-05-03 SALTS OF AN FGFR INHIBITOR AR120626A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862677040P 2018-05-04 2018-05-04

Publications (1)

Publication Number Publication Date
AR120626A1 true AR120626A1 (en) 2022-03-02

Family

ID=80996975

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP190101178A AR120626A1 (en) 2018-05-04 2019-05-03 SALTS OF AN FGFR INHIBITOR

Country Status (1)

Country Link
AR (1) AR120626A1 (en)

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