AR117605A1 - PYRAZINE DERIVATIVES FUSED AS A2A / A2B INHIBITORS - Google Patents

PYRAZINE DERIVATIVES FUSED AS A2A / A2B INHIBITORS

Info

Publication number
AR117605A1
AR117605A1 ARP190101875A ARP190101875A AR117605A1 AR 117605 A1 AR117605 A1 AR 117605A1 AR P190101875 A ARP190101875 A AR P190101875A AR P190101875 A ARP190101875 A AR P190101875A AR 117605 A1 AR117605 A1 AR 117605A1
Authority
AR
Argentina
Prior art keywords
inhibitors
pyrazine derivatives
diseases
derivatives fused
activity
Prior art date
Application number
ARP190101875A
Other languages
Spanish (es)
Inventor
xiaozhao Wang
Peter Niels Carlsen
Pei Gan
Gia Hoang
Yong Li
Chao Qi
Liangxing Wu
Wenqing Yao
Zhiyong Yu
Wenyu Zhu
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of AR117605A1 publication Critical patent/AR117605A1/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente solicitud hace referencia a compuestos de fórmula (1), o sales farmacéuticamente aceptable de este, el cual modula la actividad de receptores de adenosina, tales como los subtipos de receptores A2A y A2B, y son útiles para el tratamiento de enfermedades relacionadas a la actividad de los receptores de adenosina, lo que incluye, por ejemplo, cáncer, enfermedades inflamatorias, enfermedades cardiovasculares y enfermedades neurodegenerativas.The present application refers to compounds of formula (1), or pharmaceutically acceptable salts thereof, which modulate the activity of adenosine receptors, such as the A2A and A2B receptor subtypes, and are useful for the treatment of diseases related to the activity of adenosine receptors, including, for example, cancer, inflammatory diseases, cardiovascular diseases, and neurodegenerative diseases.

ARP190101875A 2018-07-05 2019-07-03 PYRAZINE DERIVATIVES FUSED AS A2A / A2B INHIBITORS AR117605A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862694138P 2018-07-05 2018-07-05

Publications (1)

Publication Number Publication Date
AR117605A1 true AR117605A1 (en) 2021-08-18

Family

ID=77568246

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP190101875A AR117605A1 (en) 2018-07-05 2019-07-03 PYRAZINE DERIVATIVES FUSED AS A2A / A2B INHIBITORS

Country Status (1)

Country Link
AR (1) AR117605A1 (en)

Similar Documents

Publication Publication Date Title
ECSP21007838A (en) PYRAZINE DERIVATIVES FUSED AS A2A / A2B INHIBITORS
CL2022003185A1 (en) Midazopyrimidines and triazolopyrimidines as a2a/a2b inhibitors ((sol. div. 202002198)
CL2021001984A1 (en) Pyrazolopyridines and triazolopyridines as a2a/a2b inhibitors.
CO2022003457A2 (en) Triazolopyrimidines as a2a/a2b inhibitors
ECSP21008112A (en) PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS
UY37574A (en) AZOLOPIRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS
UY37725A (en) QUINAZOLINE-PYRIDINE DERIVATIVES FOR THE TREATMENT OF CANCER-RELATED DISORDERS
UY37124A (en) NEW COMPOUNDS OF 6,7-DIHIDRO-5H-BENZO [7] REPLACED CANCELLATION, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES OF THE SAME
CR20150633A (en) BIPIRAZOL DERIVATIVES AS JAK INHIBITORS
AR094964A1 (en) USE OF PIRAZOLOPIRIMIDINE DERIVATIVES FOR THE TREATMENT OF PHOSFOINOSITIDE-RELATED 3-CINASE D (PI3Kd)
UY35898A (en) ? SYK INHIBITING COMPOUNDS AND COMPOSITIONS THAT UNDERSTAND THEM ?.
MX2020012376A (en) Fused pyrimidine derivatives as a2a / a2b inhibitors.
ECSP20061378A (en) DIOLIC AMINOPYRAZINE COMPOUNDS AS PI3K-gamma INHIBITORS
UY36875A (en) BROMODOMINIUM INHIBITING COMPOSITIONS FOR THE TREATMENT OF VARIOUS DISEASES
CL2020001047A1 (en) Fused imidazole derivatives substituted by tertiary hydroxy groups as pi3k-gamma inhibitors.
CL2019000662A1 (en) Dopamine-b-hydroxylase inhibitors.
AR117605A1 (en) PYRAZINE DERIVATIVES FUSED AS A2A / A2B INHIBITORS
ECSP18056196A (en) DERIVATIVES OF INDANO
CL2017002605A1 (en) Indole derivatives
EA202190204A1 (en) CONDENSED PYRAZINE DERIVATIVES AS A2A / A2B INHIBITORS
EA202092016A1 (en) IMIDAZOPYRIMIDINES AND TRIAZOLOPYRIMIDINES AS A2A / A2B INHIBITORS