AR117406A1 - PARENTERAL PHARMACEUTICAL COMPOSITION - Google Patents
PARENTERAL PHARMACEUTICAL COMPOSITIONInfo
- Publication number
- AR117406A1 AR117406A1 ARP190100736A ARP190100736A AR117406A1 AR 117406 A1 AR117406 A1 AR 117406A1 AR P190100736 A ARP190100736 A AR P190100736A AR P190100736 A ARP190100736 A AR P190100736A AR 117406 A1 AR117406 A1 AR 117406A1
- Authority
- AR
- Argentina
- Prior art keywords
- parenteral pharmaceutical
- treatment
- pharmaceutical composition
- patients
- neladenosone
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Composiciones farmacéuticas parenterales que comprenden L-alanil-L-alaninato de 2-{4-[2-({[2-(4-clorofenil)-1,3-tiazol-4-il]metil}sulfanil)-3,5-diciano-6-(pirrolidin-1-il)piridin-4-il]fenoxi}etilo, que también se conoce como bialanato de neladenosona, en forma de una de sus sales, un proceso para su preparación, su uso como medicamento, así como su uso para la prevención y/o el tratamiento de enfermedades cardiovasculares, por ejemplo para cardioprotección durante, y/o después de un evento cardíaco inducido por isquemia, por ejemplo después de una cirugía no cardíaca de mediano y alto riesgo, lesión por reperfusión en pacientes de STEMI, y tratamiento de pacientes agudos hospitalizados con empeoramiento de la insuficiencia cardíaca.Parenteral pharmaceutical compositions comprising 2- {4- [2 - ({[2- (4-chlorophenyl) -1,3-thiazol-4-yl] methyl} sulfanyl) -3.5 L-alanyl-L-alaninate -diciano-6- (pyrrolidin-1-yl) pyridin-4-yl] phenoxy} ethyl, which is also known as neladenosone biathanate, in the form of one of its salts, a process for its preparation, its use as a medicine, as well as its use for the prevention and / or treatment of cardiovascular diseases, for example for cardioprotection during, and / or after a cardiac event induced by ischemia, for example after a non-cardiac surgery of medium and high risk, injury by reperfusion in STEMI patients, and treatment of acute hospitalized patients with worsening heart failure.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18163467 | 2018-03-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR117406A1 true AR117406A1 (en) | 2021-08-04 |
Family
ID=61763827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP190100736A AR117406A1 (en) | 2018-03-22 | 2019-03-22 | PARENTERAL PHARMACEUTICAL COMPOSITION |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR117406A1 (en) |
WO (1) | WO2019180072A1 (en) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6407079B1 (en) | 1985-07-03 | 2002-06-18 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation |
GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
DE102009006602A1 (en) | 2009-01-29 | 2010-08-05 | Bayer Schering Pharma Aktiengesellschaft | Alkylamino-substituted dicyanopyridines and their amino acid ester prodrugs |
EP2389923B1 (en) | 2010-05-19 | 2013-01-30 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Stable ready to use injectable paracetamol formulation |
CN107531688A (en) | 2015-05-06 | 2018-01-02 | 拜耳制药股份公司 | For preparing { 4 [2 ({ [2 (4 chlorphenyls) 1 of L alanyl L alanine 2, the base of 3 thiazole 4] methyl sulfanyl) 3,5 dicyano 6 (base of pyrrolidines 1) pyridine, 4 base] phenoxy group ethyl ester monohydrochloride method |
-
2019
- 2019-03-20 WO PCT/EP2019/056943 patent/WO2019180072A1/en active Application Filing
- 2019-03-22 AR ARP190100736A patent/AR117406A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2019180072A1 (en) | 2019-09-26 |
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