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Publication of AR116010A1publicationCriticalpatent/AR116010A1/en
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents
(AREA)
Abstract
Una composición inmunógena que comprende moléculas de polisacárido O modificadas derivadas de lipopolisacáridos de E. coli y conjugados de estos. Se pueden preparar vacunas multivalentes mediante la combinación de dos o más composiciones inmunógenas monovalentes para diferentes serotipos de E. coli. Las moléculas de polisacárido O modificadas son producidas por una bacteria recombinante que incluye un gen wzz.An immunogenic composition comprising modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof. Multivalent vaccines can be prepared by combining two or more monovalent immunogenic compositions for different serotypes of E. coli. The modified O-polysaccharide molecules are produced by a recombinant bacterium that includes a wzz gene.
ARP190102409A2018-08-242019-08-23
ESCHERICHIA COLI COMPOSITIONS AND METHODS OF THEM
AR116010A1
(en)